erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vergis EN et al. | Azithromycin vs cefuroxime plus erythromycin for empirical treatment of community-acquired pneumonia in hospitalized patients: a prospective, randomized, multicenter trial. | 2000 | Arch. Intern. Med. | pmid:10809032 |
| Rachek LI et al. | Transformation of Rickettsia prowazekii to erythromycin resistance encoded by the Escherichia coli ereB gene. | 2000 | J. Bacteriol. | pmid:10809714 |
| Raimundo BC and Heathcock CH | Synthesis of a model for C7-C13 of lankamycin. | 2000 | Org. Lett. | pmid:10814237 |
| Bingen E et al. | Resistance to macrolides in Streptococcus pyogenes in France in pediatric patients. | 2000 | Antimicrob. Agents Chemother. | pmid:10817692 |
| Capobianco JO et al. | Studies of the novel ketolide ABT-773: transport, binding to ribosomes, and inhibition of protein synthesis in Streptococcus pneumoniae. | 2000 | Antimicrob. Agents Chemother. | pmid:10817709 |
| Terashi K et al. | Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells. | 2000 | Antimicrob. Agents Chemother. | pmid:10817732 |
| Munckhof WJ et al. | Postantibiotic suppression of growth of erythromycin A-susceptible and -resistant gram-positive bacteria by the ketolides telithromycin (HMR 3647) and HMR 3004. | 2000 | Antimicrob. Agents Chemother. | pmid:10817748 |
| Ueno N et al. | Erythromycin improves glycaemic control in patients with Type II diabetes mellitus. | 2000 | Diabetologia | pmid:10819233 |
| Lee B | Progressive respiratory distress in an infant treated for presumed pertussis. | 2000 | Pediatr. Infect. Dis. J. | pmid:10819348 |
| Dubois J and St-Pierre C | Comparative in vitro activity and post-antibiotic effect of gemifloxacin against Legionella spp. | 2000 | J. Antimicrob. Chemother. | pmid:10824031 |
| Gururaj VJ et al. | Triacetyloleandomycin in streptococcal throat infections. A reappraisal of an older antibiotic. | 1976 | Clin Pediatr (Phila) | pmid:1082408 |
| Watkins PB | Erythromycin breath test. | 2000 | Clin. Pharmacol. Ther. | pmid:10824637 |
| Govaerts C et al. | Investigation of unknown related substances in commercial erythromycin samples with liquid chromatography/mass spectrometry. | 2000 | Rapid Commun. Mass Spectrom. | pmid:10825252 |
| Goldman RC and Tipper DJ | Morphology and patterns of protein synthesis during sporulation of Bacillus subtilis Eryr spo(Ts) mutants. | 1979 | J. Bacteriol. | pmid:108263 |
| Zhou J et al. | Separation and determination of the macrolide antibiotics (erythromycin, spiramycin and oleandomycin) by capillary electrophoresis coupled with fast reductive voltammetric detection. | 2000 | Electrophoresis | pmid:10826680 |
| Holm M and Tärnvik A | Hospitalization due to Pasteurella multocida-infected animal bite wounds: correlation with inadequate primary antibiotic medication. | 2000 | Scand. J. Infect. Dis. | pmid:10826905 |
| Ishioka S et al. | An autopsy case of diffuse panbronchiolitis associated with lung cancer. | 2000 | Intern. Med. | pmid:10830183 |
| Usiskin SI et al. | Retreatment with clozapine after erythromycin-induced neutropenia. | 2000 | Am J Psychiatry | pmid:10831491 |
| Aarestrup FM et al. | Antimicrobial susceptibility and presence of resistance genes in staphylococci from poultry. | 2000 | Vet. Microbiol. | pmid:10831857 |
| Miyashita N et al. | In vitro susceptibility of 7.5-kb common plasmid-free Chlamydia trachomatis strains. | 2000 | Microbiol. Immunol. | pmid:10832970 |
| Privitera G et al. | Transfer of multiple antibiotic resistance between subspecies of Bacteroides fragilis. | 1979 | J. Infect. Dis. | pmid:108340 |
| Wood KE et al. | Phlegmasia cerulea dolens with compartment syndrome: a complication of femoral vein catheterization. | 2000 | Crit. Care Med. | pmid:10834724 |
| Jasir A et al. | High rate of tetracycline resistance in Streptococcus pyogenes in Iran: an epidemiological study. | 2000 | J. Clin. Microbiol. | pmid:10834960 |
| Cosgrove DM et al. | The management of Hemophilus influenzae, Type B, pericarditis. | 1976 | Ann. Thorac. Surg. | pmid:1083717 |
| Xia M et al. | Gonorrhea among men who have sex with men: outbreak caused by a single genotype of erythromycin-resistant Neisseria gonorrhoeae with a single-base pair deletion in the mtrR promoter region. | 2000 | J. Infect. Dis. | pmid:10837198 |
| Schmitz FJ et al. | Prevalence of macrolide-resistance genes in Staphylococcus aureus and Enterococcus faecium isolates from 24 European university hospitals. | 2000 | J. Antimicrob. Chemother. | pmid:10837446 |
| Jackson LA et al. | Past use of erythromycin, tetracycline, or doxycycline is not associated with risk of first myocardial infarction. | 2000 | J. Infect. Dis. | pmid:10839759 |
| Takahashi Y et al. | Accurate mass determination by multiple sprayers nano-electrospray mass spectrometry on a magnetic sector instrument. | 2000 | Rapid Commun. Mass Spectrom. | pmid:10844730 |
| Matsui S et al. | [Rheumatoid arthritis-associated bronchiolitis successfully treated with erythromycin]. | 2000 | Nihon Kokyuki Gakkai Zasshi | pmid:10846401 |
| Heikkinen T et al. | The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin. | 2000 | BJOG | pmid:10847234 |
| Thami GP and Kanwar AJ | Red facial pseudochromhidrosis. | 2000 | Br. J. Dermatol. | pmid:10848751 |
| Meisels HI and Peyman GA | Intravitreal erythromycin in the treatment of induced staphylococcal endophthalmitis. | 1976 | Ann Ophthalmol | pmid:1085597 |
| Ohmori M et al. | Effect of erythromycin on ischemia-reperfusion injury of liver in rats. | 2000 | Transplant. Proc. | pmid:10856595 |
| Alonso A et al. | Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance. | 2000 | Antimicrob. Agents Chemother. | pmid:10858330 |
| Plouffe J et al. | Clinical efficacy of intravenous followed by oral azithromycin monotherapy in hospitalized patients with community-acquired pneumonia. The Azithromycin Intravenous Clinical Trials Group. | 2000 | Antimicrob. Agents Chemother. | pmid:10858333 |
| Betriu C et al. | Comparative in vitro activities of linezolid, quinupristin-dalfopristin, moxifloxacin, and trovafloxacin against erythromycin-susceptible and -resistant streptococci. | 2000 | Antimicrob. Agents Chemother. | pmid:10858339 |
| Davies TA et al. | Antipneumococcal activity of ABT-773 compared to those of 10 other agents. | 2000 | Antimicrob. Agents Chemother. | pmid:10858350 |
| Cull SG et al. | Room-temperature ionic liquids as replacements for organic solvents in multiphase bioprocess operations. | 2000 | Biotechnol. Bioeng. | pmid:10861402 |
| Stephenson GA | Structure determination from conventional powder diffraction data: application to hydrates, hydrochloride salts, and metastable polymorphs. | 2000 | J Pharm Sci | pmid:10861598 |
| Davies JL et al. | Studies on the interaction of fermentation and microfiltration operations: erythromycin recovery from Saccharopolyspora erythraea fermentation broths. | 2000 | Biotechnol. Bioeng. | pmid:10862681 |
| Jones RN et al. | In vitro activity of selected cephalosporins and erythromycin against staphylococci and pneumococci isolated at 38 North American medical centers participating in the SENTRY Antimicrobial Surveillance Program, 1997-1998. | 2000 | Diagn. Microbiol. Infect. Dis. | pmid:10863103 |
| Wilkinson D et al. | Trial-of-antibiotic algorithm for the diagnosis of tuberculosis in a district hospital in a developing country with high HIV prevalence. | 2000 | Int. J. Tuberc. Lung Dis. | pmid:10864181 |
| Stenmark HG et al. | Biomimetic synthesis of macrolide/ketolide metabolites through a selective N-demethylation reaction. | 2000 | J. Org. Chem. | pmid:10864780 |
| Quintieri L et al. | In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A. | 2000 | Cancer Res. | pmid:10866316 |
| Fujita K et al. | Effects of macrolides on interleukin-8 secretion from human nasal epithelial cells. | 2000 | Eur Arch Otorhinolaryngol | pmid:10867834 |
| Pandey RC and Rinehart KL | Polyene antibiotics. VII. Carbon-13 nuclear magnetic resonance evidence for cyclic hemiketals in the polyene antibiotics amphotericin B, nystatin A1, tetrin A, tetrin B, lucensomycin, and pimaricin1,2. | 1976 | J. Antibiot. | pmid:1086913 |
| Cowles VE et al. | Effect of novel motilide ABT-229 versus erythromycin and cisapride on gastric emptying in dogs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10869416 |
| Kanamitsu S et al. | Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4. | 2000 | Pharm. Res. | pmid:10870985 |
| Lazarczyk DA and Duffy MC | Erythromycin-induced primary biliary cirrhosis. | 2000 | Dig. Dis. Sci. | pmid:10877225 |
| Yan JJ et al. | Prevalence of polyclonal mefA-containing isolates among erythromycin-resistant group A streptococci in Southern Taiwan. | 2000 | J. Clin. Microbiol. | pmid:10878028 |