erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Huang M et al. | Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. | 2015 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26223917 |
Schneider SC et al. | Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland. | 2015 | Antimicrob. Agents Chemother. | pmid:26195516 |
Takagi M et al. | Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. | 2015 | Drug Metab. Pharmacokinet. | pmid:26195223 |
Aydin S et al. | Development of antibiotic resistance genes in microbial communities during long-term operation of anaerobic reactors in the treatment of pharmaceutical wastewater. | 2015 | Water Res. | pmid:26188597 |
Gaudreau C et al. | Long-Lasting Outbreak of Erythromycin- and Ciprofloxacin-Resistant Campylobacter jejuni Subspecies jejuni From 2003 to 2013 in Men Who Have Sex With Men, Quebec, Canada. | 2015 | Clin. Infect. Dis. | pmid:26187024 |
Dayie NT et al. | Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children. | 2015 | Microb. Drug Resist. | pmid:26172078 |
He M et al. | Dynamics of serotype 14 Streptococcus pneumoniae population causing acute respiratory infections among children in China (1997-2012). | 2015 | BMC Infect. Dis. | pmid:26163293 |
Piccinelli G et al. | Characterization and antibiotic susceptibility of Streptococcus agalactiae isolates causing urinary tract infections. | 2015 | Infect. Genet. Evol. | pmid:26144658 |
Wang P et al. | Serotype distribution, antimicrobial resistance, and molecular characterization of invasive group B Streptococcus isolates recovered from Chinese neonates. | 2015 | Int. J. Infect. Dis. | pmid:26141418 |
Høye S | An extraordinary tale of an ordinary case. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130550 |
Fayed B et al. | Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. | 2015 | Appl. Environ. Microbiol. | pmid:26431970 |
Loose LM et al. | Adolescent with respiratory impairments and short-lived fever. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130549 |
Liu J et al. | Preparation and characterization of erythromycin molecularly imprinted polymers based on distillation-precipitation polymerization. | 2015 | J Sep Sci | pmid:26118901 |
Fathollahipour S et al. | Electrospinning of PVA/chitosan nanocomposite nanofibers containing gelatin nanoparticles as a dual drug delivery system. | 2015 | J Biomed Mater Res A | pmid:26112829 |
Xing L et al. | ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer. | 2015 | PLoS ONE | pmid:26107936 |
Dridi B et al. | Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. | 2015 | Antimicrob. Agents Chemother. | pmid:26100702 |
Vlakh EG et al. | Preparation and characterization of macroporous monoliths imprinted with erythromycin. | 2015 | J Sep Sci | pmid:26033867 |
Wang L et al. | Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. | 2015 | Lett. Appl. Microbiol. | pmid:26031793 |
Wang Z et al. | MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. | 2015 | PLoS ONE | pmid:25706647 |
Yoon IA et al. | Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. | 2015 | Int. J. Infect. Dis. | pmid:26026823 |
Gherardi G et al. | Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. | 2015 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:26024763 |
Reveiz L and Cardona AF | Antibiotics for acute laryngitis in adults. | 2015 | Cochrane Database Syst Rev | pmid:26002823 |
Pesola AK et al. | Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. | 2015 | Euro Surveill. | pmid:25990232 |
Sun XJ et al. | Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25957293 |
Guo MT et al. | Insights into the amplification of bacterial resistance to erythromycin in activated sludge. | 2015 | Chemosphere | pmid:25957255 |
Kasai A et al. | Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. | 2015 | J. Med. Microbiol. | pmid:25934551 |
Melkumyan AR et al. | Effects of antibiotic treatment on the lactobacillus composition of vaginal microbiota. | 2015 | Bull. Exp. Biol. Med. | pmid:25894774 |
Romaniszyn D et al. | Epidemiology, antibiotic consumption and molecular characterisation of Staphylococcus aureus infections--data from the Polish Neonatology Surveillance Network, 2009-2012. | 2015 | BMC Infect. Dis. | pmid:25888217 |
Park JY et al. | Construction of a shuttle vector based on the small cryptic plasmid pJY33 from Weissella cibaria 33. | 2015 | Plasmid | pmid:25882072 |
Jakubů V et al. | Minimum inhibitory concentrations of erythromycin and other antibiotics for Czech strains of Bordetella pertussis. | 2015 | Epidemiol Mikrobiol Imunol | pmid:25872990 |
Koutsogiannidis CP et al. | Decreased DNA Disruption in the Porcine Neocortex with Erythromycin Preconditioning during Prolonged Hypothermic Circulatory Arrest: Evidence for Neuroprotection. | 2015 | J Card Surg | pmid:25858150 |
KovaÄ J et al. | Antibiotic resistance modulation and modes of action of (-)-α-pinene in Campylobacter jejuni. | 2015 | PLoS ONE | pmid:25830640 |
Abukar AA et al. | Unusual cause of infective endocarditis in an elderly patient with a rare condition. | 2015 | BMJ Case Rep | pmid:25820110 |
Aydin S et al. | Combined effect of erythromycin, tetracycline and sulfamethoxazole on performance of anaerobic sequencing batch reactors. | 2015 | Bioresour. Technol. | pmid:25817031 |
Cui B et al. | Effects of erythromycin on the phenotypic and genotypic biofilm expression in two clinical Staphylococcus capitis subspecies and a functional analysis of Ica proteins in S. capitis. | 2015 | J. Med. Microbiol. | pmid:25813821 |
Chew ML et al. | Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial. | 2015 | Clin Drug Investig | pmid:25808394 |
Hersch M et al. | Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. | 2015 | J Crit Care | pmid:25746849 |
Lee S et al. | Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB. | 2015 | J. Microbiol. | pmid:25740377 |
Lysnyansky I et al. | Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. | 2015 | Microb. Drug Resist. | pmid:25734368 |
Abreu AC et al. | Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. | 2015 | Microb. Drug Resist. | pmid:25734256 |
Ou H et al. | Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. | 2015 | J. Hazard. Mater. | pmid:25704432 |
Ikebe T et al. | Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. | 2015 | Epidemiol. Infect. | pmid:25703404 |
Li Y et al. | Where macrolide resistance is prevalent. | 2015 | APMIS | pmid:25703275 |
Chemler JA et al. | Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination. | 2015 | J. Am. Chem. Soc. | pmid:26230368 |
Choi JH et al. | Distribution of emm types among group A Streptococcus isolates from children in Korea. | 2015 | Diagn. Microbiol. Infect. Dis. | pmid:25700867 |
Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
Sessa R et al. | Effects of Mentha suaveolens essential oil on Chlamydia trachomatis. | 2015 | Biomed Res Int | pmid:25685793 |
Shi JG et al. | Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib. | 2015 | Clin. Pharmacol. Ther. | pmid:25670523 |
Xu CW et al. | First report of macrolide resistance gene erm(T) harbored by a novel small plasmid from Erysipelothrix rhusiopathiae. | 2015 | Antimicrob. Agents Chemother. | pmid:25666150 |
Naquin A et al. | Presence of antibiotic resistance genes in a sewage treatment plant in Thibodaux, Louisiana, USA. | 2015 | Bioresour. Technol. | pmid:25662190 |
GarcÃa-Mayor MA et al. | Occurrence of erythromycin residues in sheep milk. Validation of an analytical method. | 2015 | Food Chem. Toxicol. | pmid:25637760 |
van Eijk E et al. | Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5. | 2015 | BMC Genomics | pmid:25636331 |
Gao P et al. | Impacts of coexisting antibiotics, antibacterial residues, and heavy metals on the occurrence of erythromycin resistance genes in urban wastewater. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25631280 |
Chan BC et al. | Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. | 2015 | J. Pharm. Pharmacol. | pmid:25212982 |
Lin X et al. | Macrolides for diffuse panbronchiolitis. | 2015 | Cochrane Database Syst Rev | pmid:25618845 |
Sakata H | The change of macrolide resistance rates in group A Streptococcus isolates from children between 2002 and 2013 in Asahikawa city. | 2015 | J. Infect. Chemother. | pmid:25618777 |
Johnson AC et al. | Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers. | 2015 | Sci. Total Environ. | pmid:25617699 |
Wang P et al. | Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas. | 2015 | Microb. Cell Fact. | pmid:25612661 |
Nagelreiter C et al. | Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. | 2015 | Int J Pharm | pmid:25475015 |
Harmer CJ et al. | A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. | 2015 | J. Antimicrob. Chemother. | pmid:25468903 |
Wan J et al. | Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. | 2015 | J. Hazard. Mater. | pmid:25464321 |
Zhou Z et al. | Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. | 2015 | Antimicrob. Agents Chemother. | pmid:25451048 |
Hur J et al. | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | 2015 | Chem. Res. Toxicol. | pmid:25811541 |
Haxel BR et al. | Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis. | 2015 | Laryngoscope | pmid:25425539 |
Berg C et al. | Significance of archaeal nitrification in hypoxic waters of the Baltic Sea. | 2015 | ISME J | pmid:25423026 |
Blix HS et al. | Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance? | 2015 | Epidemiol. Infect. | pmid:25388750 |
MarÃn M et al. | Clostridium difficile isolates with high linezolid MICs harbor the multiresistance gene cfr. | 2015 | Antimicrob. Agents Chemother. | pmid:25385106 |
Igbinosa IH | Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals. | 2015 | Trop Anim Health Prod | pmid:25348646 |
Kam Y et al. | Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". | 2015 | Int. J. Cancer | pmid:25156304 |
Chen Y et al. | The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. | 2015 | Bioprocess Biosyst Eng | pmid:25042891 |
Llorca M et al. | Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. | 2015 | Chemosphere | pmid:24972175 |
Lo HH et al. | Antibiotic susceptibility pattern and erythromycin resistance mechanisms in beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates from central Taiwan. | 2015 | J Microbiol Immunol Infect | pmid:24856419 |
Mazur CS et al. | P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. | 2015 | Toxicol. Lett. | pmid:25268938 |
Muralidharan V and Striepen B | Teaching old drugs new tricks to stop malaria invasion in its tracks. | 2015 | BMC Biol. | pmid:26349580 |
Song LY et al. | Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action. | 2015 | Antimicrob. Agents Chemother. | pmid:26711761 |
Cochrane SA et al. | Synthesis of Tridecaptin-Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria. | 2015 | J. Med. Chem. | pmid:26636619 |
Liang Z et al. | Structural Correspondence of the Oriented Attachment Growth Mechanism of Crystals of the Pharmaceutical Dirithromycin. | 2015 | Langmuir | pmid:26632998 |
Shishkina AV et al. | Modeling Interactions of Erythromycin Derivatives with Ribosomes. | 2015 | Biochemistry Mosc. | pmid:26615442 |
Li X et al. | Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility. | 2015 | Sci Rep | pmid:26607739 |
Cheng C et al. | Ciprofloxacin plus erythromycin or ambroxol ameliorates endotracheal tube-associated Pseudomonas aeruginosa biofilms in a rat model. | 2015 | Pathol. Res. Pract. | pmid:26601615 |
Wilson DW et al. | Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. | 2015 | BMC Biol. | pmid:26187647 |
Yi X et al. | Improved detection of multiple environmental antibiotics through an optimized sample extraction strategy in liquid chromatography-mass spectrometry analysis. | 2015 | Anal Bioanal Chem | pmid:26449847 |
Ayazi P et al. | Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. | 2015 | Prague Med Rep | pmid:26445390 |
Yamaguchi M et al. | Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. | 2015 | Cell Rep | pmid:26440893 |
Chazan B et al. | Susceptibility of Group A Streptococcus to Antimicrobial Agents in Northern Israel: A Surveillance Study. | 2015 | Microb. Drug Resist. | pmid:26430943 |
Kojima C et al. | Distribution of Antimicrobial Resistance in Campylobacter Strains Isolated from Poultry at a Slaughterhouse and Supermarkets in Japan. | 2015 | Biocontrol Sci | pmid:26412697 |
Hoffmann K et al. | Prevalence and resistance patterns of commensal S. aureus in community-dwelling GP patients and socio-demographic associations. A cross-sectional study in the framework of the APRES-project in Austria. | 2015 | BMC Infect. Dis. | pmid:25981559 |
Yang Y et al. | Variation in Bordetella pertussis Susceptibility to Erythromycin and Virulence-Related Genotype Changes in China (1970-2014). | 2015 | PLoS ONE | pmid:26406905 |
O'Connor SE | Engineering of Secondary Metabolism. | 2015 | Annu. Rev. Genet. | pmid:26393965 |
Borges V et al. | Helicobacter pullorum isolated from fresh chicken meat: antibiotic resistance and genomic traits of an emerging foodborne pathogen. | 2015 | Appl. Environ. Microbiol. | pmid:26386065 |
Dixit S and Park JH | Enantioseparation of basic chiral drugs on a carbamoylated erythromycin-zirconia hybrid monolith using capillary electrochromatography. | 2015 | J Chromatogr A | pmid:26372443 |
Michael-Kordatou I et al. | Erythromycin oxidation and ERY-resistant Escherichia coli inactivation in urban wastewater by sulfate radical-based oxidation process under UV-C irradiation. | 2015 | Water Res. | pmid:26360228 |
Arinto-Garcia R et al. | Comparing Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and Phenotypic and Molecular Methods for Identification of Species within the Streptococcus anginosus Group. | 2015 | J. Clin. Microbiol. | pmid:26354817 |
Han X et al. | Synthesis and structure-activity relationships of novel 9-oxime acylides with improved bactericidal activity. | 2015 | Bioorg. Med. Chem. | pmid:26349628 |
Ozbayram EG et al. | Acute effects of various antibiotic combinations on acetoclastic methanogenic activity. | 2015 | Environ Sci Pollut Res Int | pmid:25408075 |
Peyre L et al. | High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. | 2015 | Toxicol In Vitro | pmid:26239606 |
Aydın S et al. | The joint acute effect of tetracycline, erythromycin and sulfamethoxazole on acetoclastic methanogens. | 2015 | Water Sci. Technol. | pmid:25909721 |
Banik A et al. | Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital. | 2015 | J Infect Dev Ctries | pmid:26230122 |
Wang Z et al. | Direct Detection of Erythromycin-Resistant Bordetella pertussis in Clinical Specimens by PCR. | 2015 | J. Clin. Microbiol. | pmid:26224847 |
Olivieri R et al. | Evolution of macrolide resistance in Streptococcus pyogenes over 14 years in an area of central Italy. | 2015 | J. Med. Microbiol. | pmid:26224594 |