erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Frick PA et al. | Prevalence of antimicrobial drug-resistant Streptococcus pneumoniae in Washington State. | 1998 | West. J. Med. | pmid:9866434 |
Kataja J et al. | Erythromycin resistance genes in group A streptococci in Finland. The Finnish Study Group for Antimicrobial Resistance. | 1999 | Antimicrob. Agents Chemother. | pmid:9869564 |
Faghih R et al. | Preparation of 9-deoxo-4"-deoxy-6,9-epoxyerythromycin lactams "motilactides": potent and orally active prokinetic agents. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871545 |
Waddell ST et al. | Synthesis and antibacterial activity of O-methyl derivatives of azalide antibiotics: I. 4", 11 and 12-OMe derivatives via direct methylation. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871616 |
Brand RE et al. | Gastroparesis as a cause of nausea and vomiting after high-dose chemotherapy and haemopoietic stem-cell transplantation. | 1998 Dec 19-26 | Lancet | pmid:9872252 |
Denis A and Agouridas C | Synthesis of 6-O-methyl-azithromycin and its ketolide analogue via Beckmann rearrangement of 9(E)-6-O-methyl-erythromycin oxime. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873555 |
Sol V et al. | Nitroglycosylated meso-arylporphyrins as photoinhibitors of gram positive bacteria. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873665 |
Manna PK and Basu SK | Preparation and evaluation of erythromycin fumarate--a new derivative of erythromycin. | 1998 | Drug Dev Ind Pharm | pmid:9876541 |
Zgurskaya HI and Nikaido H | AcrA is a highly asymmetric protein capable of spanning the periplasm. | 1999 | J. Mol. Biol. | pmid:9878415 |
Muller-Serieys C | [Bacterial resistance and new therapeutic perspectives]. | 1998 | Presse Med | pmid:9879336 |
Khanna M et al. | Selection of suitable marker genes for the development of cloning vectors and electroporation in different strains of Amycolatopsis mediterranei. | 1998 | Microbiol. Res. | pmid:9880927 |
Riippi M et al. | The effect of compression force on surface structure, crushing strength, friability and disintegration time of erythromycin acistrate tablets. | 1998 | Eur J Pharm Biopharm | pmid:9885307 |
Wu K et al. | Enterococcus faecalis pheromone-responding plasmid pAD1 gives rise to an aggregation (clumping) response when cells are exposed to subinhibitory concentrations of chloramphenicol, erythromycin, or tetracycline. | 1999 | Plasmid | pmid:9887311 |
El Younis CM et al. | Rapid marked response of severe hyperemesis gravidarum to oral erythromycin. | 1998 | Am J Perinatol | pmid:9890250 |
Akiyama H et al. | Streptococci isolated from various skin lesions: the interaction with Staphylococcus aureus strains. | 1999 | J. Dermatol. Sci. | pmid:9890370 |
Matsubara S et al. | [Severe Legionella micdadei pneumonia effectively treated with hemofiltration therapy]. | 1998 | Nihon Kokyuki Gakkai Zasshi | pmid:9893432 |
Ziermann R and Betlach MC | Recombinant polyketide synthesis in Streptomyces: engineering of improved host strains. | 1999 | BioTechniques | pmid:9894599 |
Karbowski M et al. | Free radical-induced megamitochondria formation and apoptosis. | 1999 | Free Radic. Biol. Med. | pmid:9895232 |
Petersdorf RG | Antimicrobial prophylaxis of bacterial endocarditis. Prudent caution or bacterial overkill? | 1978 | Am. J. Med. | pmid:99033 |
Kaji M et al. | [Effects of long-term preoperative administration of low-dose erythromycin on warm ischemia-reperfusion pulmonary injury]. | 1998 | Nihon Kokyuki Gakkai Zasshi | pmid:9916477 |