erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Intestinal Atresia D007409 3 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Dry Socket D004368 3 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Empyema D004653 3 associated lipids
Erythema Multiforme D004892 3 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Orthomyxoviridae Infections D009976 3 associated lipids
Superinfection D015163 3 associated lipids
Scleritis D015423 3 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Toothache D014098 3 associated lipids
Meningitis, Haemophilus D008583 3 associated lipids
Porphyrias D011164 2 associated lipids
Periodontal Abscess D010508 2 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Pancreatic Fistula D010185 2 associated lipids
Furunculosis D005667 2 associated lipids
Pericoronitis D010497 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Protein-Losing Enteropathies D011504 2 associated lipids
Hypoventilation D007040 2 associated lipids
Bites, Human D001734 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Uterine Cervical Erosion D002579 2 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Common Cold D003139 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Animal Diseases D000820 2 associated lipids
Dental Enamel Hypoplasia D003744 2 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Torsades de Pointes D016171 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Diphtheria D004165 2 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Gastroparesis D018589 2 associated lipids
Hoarseness D006685 2 associated lipids
Marfan Syndrome D008382 2 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Vulvovaginitis D014848 2 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Salpingitis D012488 2 associated lipids
Nasopharyngitis D009304 2 associated lipids
Dysarthria D004401 2 associated lipids
Factor X Deficiency D005171 2 associated lipids
Elephantiasis D004604 2 associated lipids
Mastoiditis D008417 2 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Postgastrectomy Syndromes D011178 2 associated lipids
Ehrlichiosis D016873 2 associated lipids
Herpes Genitalis D006558 2 associated lipids
Hearing Loss, Functional D006315 2 associated lipids
Onychomycosis D014009 2 associated lipids
Tooth Fractures D014082 2 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Pneumonia, Staphylococcal D011023 2 associated lipids
Gardner Syndrome D005736 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
Rubella D012409 2 associated lipids
Seroma D049291 2 associated lipids
Bile Reflux D001655 2 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Choanal Atresia D002754 1 associated lipids
Scarlet Fever D012541 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Dacryocystitis D003607 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Sialadenitis D012793 1 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Jiang M and Pfeifer BA Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. 2013 Metab. Eng. pmid:23747605
Xia Q et al. Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. 2013 BMC Microbiol. pmid:23767761
Guo MT et al. Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. 2013 Chemosphere pmid:24055024
Ong SJ et al. Staphylococcus aureus keratitis: a review of hospital cases. 2013 PLoS ONE pmid:24244625
Chroboczek T et al. Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. 2013 PLoS ONE pmid:24260092
Petráčková D et al. Fitness and proteome changes accompanying the development of erythromycin resistance in a population of Escherichia coli grown in continuous culture. 2013 Microbiologyopen pmid:23996919
Weber JM et al. Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations. 2013 Appl. Microbiol. Biotechnol. pmid:23604533
Li X et al. Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. 2013 Eur J Med Chem pmid:23229056
Nunez-Samudio V and Chesneau O Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. 2013 Res. Microbiol. pmid:23261969
Heelan K et al. Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. 2012 Sep-Oct Pediatr Dermatol pmid:21906149
Lian W et al. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. 2012 Oct-Dec Biosens Bioelectron pmid:22683249
Hapa A et al. Childhood pityriasis lichenoides and oral erythromycin. 2012 Nov-Dec Pediatr Dermatol pmid:22639857
Asai N et al. A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. 2012 Nov-Dec J Bras Pneumol pmid:23288130
Clementson B and Smidt AC Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. 2012 May-Jun Pediatr Dermatol pmid:22122785
Kuhn M et al. Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. 2012 Jul-Aug Berl. Munch. Tierarztl. Wochenschr. pmid:22919930
Jiang RS et al. Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. 2012 Jul-Aug Am J Rhinol Allergy pmid:22801017
Kuehne SA and Minton NP ClosTron-mediated engineering of Clostridium. 2012 Jul-Aug Bioengineered pmid:22750794
Miguel AI et al. Pediatric ocular rosacea: 2 cases. 2012 Jul-Aug Eur J Ophthalmol pmid:22267454
Amatya A et al. Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. 2012 Jan-Mar Kathmandu Univ Med J (KUMJ) pmid:22971864
Zhang H et al. Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. 2012 Jan-Feb Biotechnol. Prog. pmid:21905273
Pehr K Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. 2012 Jan-Feb J Cutan Med Surg pmid:22417996
Abdel Fattah NS and Darwish YW Antibiogram testing of pediatric skin infections in the era of methicillin-resistant Staphylococci aureus: an Egyptian University Hospital-based study. 2012 Int. J. Dermatol. pmid:22928620
Kjeldgaard J et al. Residual antibiotics disrupt meat fermentation and increase risk of infection. 2012 MBio pmid:22930338
Sakatis MZ et al. Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. 2012 Chem. Res. Toxicol. pmid:22931300
Krasniqi S et al. Blood, tissue, and intracellular concentrations of erythromycin and its metabolite anhydroerythromycin during and after therapy. 2012 Antimicrob. Agents Chemother. pmid:22083477
Nimgaonkar A et al. Gastrointestinal dysmotility. 2012 Dig. Dis. Sci. pmid:22038542
Fazeli M et al. Erythromycin enhances abomasal emptying in healthy unweaned lambs as shown by acetaminophen absorption test. 2012 J. Vet. Pharmacol. Ther. pmid:22066489
Kumar R et al. Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. 2012 Bioorg. Med. Chem. Lett. pmid:22153939
Reutenauer-Patte J et al. Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. 2012 Am. J. Pathol. pmid:22192627
Villaseñor-Sierra A et al. Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. 2012 Int. J. Infect. Dis. pmid:22217469
Luangtongkum T et al. Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. 2012 Antimicrob. Agents Chemother. pmid:22183170
Romøren M et al. Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway. 2012 Br J Clin Pharmacol pmid:22463376
Lee CH et al. Case-crossover design: an alternative strategy for detecting drug-induced liver injury. 2012 J Clin Epidemiol pmid:22445086
Blode H et al. Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. 2012 Contraception pmid:22445438
Kanazu T et al. Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. 2012 Biopharm Drug Dispos pmid:22447511
Sui Q et al. Identification of priority pharmaceuticals in the water environment of China. 2012 Chemosphere pmid:22591850
Constable PD et al. Evidence-based use of prokinetic drugs for abomasal disorders in cattle. 2012 Vet. Clin. North Am. Food Anim. Pract. pmid:22374117
Mehra T et al. Treatment of severe acne with low-dose isotretinoin. 2012 Acta Derm. Venereol. pmid:22377969
Ogawa W et al. Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. 2012 Gene pmid:22391093
Diacon AH et al. Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. 2012 Antimicrob. Agents Chemother. pmid:22391540
El-Adawy H et al. Determination of antimicrobial sensitivities of Campylobacter jejuni isolated from commercial turkey farms in Germany. 2012 Avian Dis. pmid:23397839
Mercer BM et al. The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. 2012 Am. J. Obstet. Gynecol. pmid:22000668
Pendela M et al. Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. 2012 Anal Bioanal Chem pmid:22002558
Wilson BB et al. An atypical presentation of erythrasma. 2012 J. Am. Acad. Dermatol. pmid:23062922
Zhou L et al. Molecular characteristics of erythromycin-resistant Streptococcus pneumoniae from pediatric patients younger than five years in Beijing, 2010. 2012 BMC Microbiol. pmid:23043378
Cannon JA et al. Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. 2012 Dis. Colon Rectum pmid:23044677
Kaul M et al. A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. 2012 J. Med. Chem. pmid:23050700
Du Plessis LH et al. In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum. 2012 J. Antibiot. pmid:23093037
Marks LR et al. The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents. 2012 PLoS ONE pmid:22905269
Weisman LE et al. Appropriate antibiotic therapy improves Ureaplasma sepsis outcome in the neonatal mouse. 2012 Pediatr. Res. pmid:22907617