erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Vanhoof R et al. | In vitro susceptibilities of 176 clinical isolates of Streptococcus pneumoniae to 11 beta-lactams, erythromycin, and tetracycline. | 1996 | Acta Clin Belg | pmid:8997755 |
YOURASSOWSKY E and BEUMER J | [EPIDEMIOLOGICAL STUDY OF STAPHYLOCOCCUS AUREUS INFECTIONS AT THE BRUGMANN HOSPITAL]. | 1963 | Acta Clin Belg | pmid:14045898 |
Monsieur I et al. | Severe community-acquired pneumonia caused by atypical organisms. | 1997 | Acta Clin Belg | pmid:9204587 |
Vanhoof R et al. | In vitro evaluation of the antibiotic susceptibility of Streptococcus pneumoniae: pneumococci relatively resistant to penicillin in Brussels. | 1980 | Acta Clin Belg | pmid:6916583 |
Biver A et al. | [Coagulase positive staphylococci isolated from victims of severe burns]. | 1971 | Acta Chir. Belg. | pmid:4948663 |
WICKMAN K | Nosocomial infection with erythromycin-resistant straphylococci in a burns and plastic surgery unit. | 1958 | Acta Chir Scand | pmid:13532327 |
Kocik L and Crnjakovic D | [Injuries of the peripheral blood vessels]. | 1976 | Acta Chir Iugosl | pmid:779378 |
Gottfredsson M and SteingrÃmsdóttir H | Disseminated invasive aspergillosis in a patient with acute leukaemia. | 2006 | Acta Biomed | pmid:16918060 |
Olajuyigbe OO et al. | In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. | 2017 | Acta Biochim. Pol. | pmid:28612062 |
Klita S and Szafranśki P | Comparison of the mechanism of action of cyclic 11,12-erythromycin A carbonate and erythromycin A. | 1980 | Acta Biochim. Pol. | pmid:7023159 |