erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Rickettsia Infections D012282 5 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Rosacea D012393 13 associated lipids
Rubella D012409 2 associated lipids
Salpingitis D012488 2 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Scarlet Fever D012541 1 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Seizures D012640 87 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Sialadenitis D012793 1 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Sinusitis D012852 9 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Skin Neoplasms D012878 12 associated lipids
Skin Ulcer D012883 6 associated lipids
Splenic Infarction D013159 1 associated lipids
Splenomegaly D013163 4 associated lipids
Sporotrichosis D013174 3 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Stomach Diseases D013272 7 associated lipids
Stomatitis D013280 14 associated lipids
Streptococcal Infections D013290 4 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Synovitis D013585 15 associated lipids
Syphilis D013587 6 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Syphilis, Latent D013592 4 associated lipids
Tachycardia D013610 7 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Thromboembolism D013923 6 associated lipids
Thyroid Crisis D013958 1 associated lipids
Onychomycosis D014009 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Tooth Fractures D014082 2 associated lipids
Tooth, Impacted D014095 9 associated lipids
Toothache D014098 3 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Tremor D014202 15 associated lipids
Trench Fever D014205 1 associated lipids
Trisomy D014314 6 associated lipids
Tuberculosis D014376 20 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Typhus, Endemic Flea-Borne D014437 3 associated lipids
Typhus, Epidemic Louse-Borne D014438 1 associated lipids
Uremia D014511 33 associated lipids
Urethral Diseases D014522 4 associated lipids
Urethritis D014526 9 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Urticaria D014581 13 associated lipids
Uveitis D014605 14 associated lipids
Varicose Ulcer D014647 4 associated lipids
Vibrio Infections D014735 5 associated lipids
Vomiting D014839 21 associated lipids
Vulvovaginitis D014848 2 associated lipids
Whooping Cough D014917 6 associated lipids
Wound Infection D014946 12 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Xerostomia D014987 6 associated lipids
Yaws D015001 4 associated lipids
Superinfection D015163 3 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Scleritis D015423 3 associated lipids
Weight Gain D015430 101 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Torsades de Pointes D016171 2 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Bacteremia D016470 9 associated lipids
Foot Ulcer D016523 4 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Critical Illness D016638 13 associated lipids
Empyema, Pleural D016724 2 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ehrlichiosis D016873 2 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Chalazion D017043 1 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Nie XP et al. Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole exposure to the antioxidant system in Pseudokirchneriella subcapitata. 2013 Environ. Pollut. pmid:22982550
Berghaus LJ et al. Mutant prevention concentration and mutant selection window for 10 antimicrobial agents against Rhodococcus equi. 2013 Vet. Microbiol. pmid:23915992
Janssen P et al. The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. 2013 Am. J. Gastroenterol. pmid:24005344
Parrott N et al. An unusual cause of persistent postpartum vaginal discharge. 2013 Int J STD AIDS pmid:23970614
Pelchovich G et al. The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics. 2013 Int. J. Med. Microbiol. pmid:23972615
Ishihara K et al. Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan. 2013 Microbiol. Immunol. pmid:23930694
Pedersen JM et al. Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). 2013 Toxicol. Sci. pmid:24014644
Zhang L et al. Design, synthesis and biological evaluation of azithromycin glycosyl derivatives as potential antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23937982
Hirano E et al. Erythromycin treatment suppresses myocardial injury in autoimmune myocarditis in rats via suppression of superoxide production. 2013 Int. J. Cardiol. pmid:22727964
Sripriya J et al. Laser receptive polyelectrolyte thin films doped with biosynthesized silver nanoparticles for antibacterial coatings and drug delivery applications. 2013 Int J Pharm pmid:24096301
Wang HB et al. Molecular epidemiological analysis of group A Streptococci isolated from children in Chaoyang District of Beijing, 2011: emm types, virulence factor genes and erythromycin resistant genes. 2013 Biomed. Environ. Sci. pmid:24099615
Wang X et al. Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. 2013 ACS Appl Mater Interfaces pmid:24150740
Kelley C et al. Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. 2013 Eur J Med Chem pmid:23314053
González-Pleiter M et al. Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: implications for environmental risk assessment. 2013 Water Res. pmid:23399078
Odhav A et al. Subconjunctival latex paint from occupational injury. 2013 J Emerg Med pmid:23399395
Ziesenitz VC et al. Cytochrome P450-3A phenotyping using midazolam is not altered by OATP1B1 polymorphisms. 2013 Clin. Pharmacol. Ther. pmid:23549145
Kirm B et al. SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea. 2013 Microb. Cell Fact. pmid:24341557
Olender A et al. The cause of Actinomyces canalictulis--a case study. 2013 Ann Agric Environ Med pmid:24364446
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
Basak R and Bandyopadhyay R Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH. 2013 Langmuir pmid:23472840
Broad J and Sanger GJ The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. 2013 Br. J. Pharmacol. pmid:23190027
Hao H et al. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. 2013 Antimicrob. Agents Chemother. pmid:23274667
Yang J et al. Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity. 2013 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:23474502
Zhang Q et al. High-resolution melting analysis for the detection of two erythromycin-resistant Bordetella pertussis strains carried by healthy schoolchildren in China. 2013 Clin. Microbiol. Infect. pmid:23480481
Prabu D and Menon T Genotyping of erythromycin resistant group C & G streptococci isolated in Chennai, south India. 2013 Indian J. Med. Res. pmid:23481067
Zhang Y et al. Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23481648
Koulaouzidis A et al. Do prokinetics influence the completion rate in small-bowel capsule endoscopy? A systematic review and meta-analysis. 2013 Curr Med Res Opin pmid:23790243
Sundermann U et al. Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. 2013 ACS Chem. Biol. pmid:23181268
Roberts DW What is the role of antibiotic-containing cement in total knee arthroplasty? 2013 J Bone Joint Surg Am pmid:23636201
Sun W et al. [Glycosyl isomerization based on the biosynthesis of natural-product sugar from microorganism]. 2013 Yao Xue Xue Bao pmid:23672013
Wang H et al. High prevalence of fluoroquinolone-resistant group B streptococci among clinical isolates in China and predominance of sequence type 19 with serotype III. 2013 Antimicrob. Agents Chemother. pmid:23295933
Everson GT et al. Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy. 2013 Liver Transpl. pmid:23239552
Kelmer G et al. Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic, or palmar digital veins in standing horses. 2013 J. Vet. Pharmacol. Ther. pmid:23240633
Pelchovich G et al. Effect of ribosome-targeting antibiotics on streptomycin-resistant Mycobacterium mutants in the rpsL gene. 2013 Int. J. Antimicrob. Agents pmid:23664678
Oplinger RW and Wagner EJ Control of Flavobacterium psychrophilum: tests of erythromycin, streptomycin, osmotic and thermal shocks, and rapid pH change. 2013 J. Aquat. Anim. Health pmid:23241009
Li N et al. Effect of corilagin on membrane permeability of Escherichia coli, Staphylococcus aureus and Candida albicans. 2013 Phytother Res pmid:23192753
Chae HS et al. Use of a novel Escherichia coli-leuconostoc shuttle vector for metabolic engineering of Leuconostoc citreum to overproduce D-lactate. 2013 Appl. Environ. Microbiol. pmid:23241984
Papapetropoulos N et al. Abscesses and wound infections due to Staphylococcus lugdunensis: report of 16 cases. 2013 Infection pmid:23242962
Romeiro FG et al. Erythromycin versus neomycin in the treatment of hepatic encephalopathy in cirrhosis: a randomized double-blind study. 2013 BMC Gastroenterol pmid:23324408
Elens L et al. Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin. 2013 Pharmacogenet. Genomics pmid:23324807
Boutouyrie-Dumont B An aide memoire for model-based drug development--a new key for the interpretation of the erythromycin breath test--therapeutic index as a biomarker for smart drug development. 2013 Biomark Med pmid:23387489
Liang JH et al. Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. 2013 Bioorg. Med. Chem. Lett. pmid:23375796
Drago L et al. Phenotypic and genotypic antibiotic resistance in some probiotics proposed for medical use. 2013 Int. J. Antimicrob. Agents pmid:23313535
Sanger GJ et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. 2013 Br. J. Pharmacol. pmid:23189978
Rams TE et al. Antibiotic susceptibility of periodontal Enterococcus faecalis. 2013 J. Periodontol. pmid:23106507
Gómez-Sanz E et al. Analysis of a novel erm(T)- and cadDX-carrying plasmid from methicillin-susceptible Staphylococcus aureus ST398-t571 of human origin. 2013 J. Antimicrob. Chemother. pmid:23075692
Serisier DJ et al. Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. 2013 JAMA pmid:23532242
Elborn JS and Tunney MM Macrolides and bronchiectasis: clinical benefit with a resistance price. 2013 JAMA pmid:23532247
Chan BC et al. Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase. 2013 Phytomedicine pmid:23541215
Tarran R et al. Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. 2013 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:23542952