erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Rickettsia Infections D012282 5 associated lipids
Rickettsiaceae Infections D012288 2 associated lipids
Rosacea D012393 13 associated lipids
Rubella D012409 2 associated lipids
Salpingitis D012488 2 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Scarlet Fever D012541 1 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Seizures D012640 87 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Sialadenitis D012793 1 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Sinusitis D012852 9 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Skin Neoplasms D012878 12 associated lipids
Skin Ulcer D012883 6 associated lipids
Splenic Infarction D013159 1 associated lipids
Splenomegaly D013163 4 associated lipids
Sporotrichosis D013174 3 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Stomach Diseases D013272 7 associated lipids
Stomatitis D013280 14 associated lipids
Streptococcal Infections D013290 4 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Synovitis D013585 15 associated lipids
Syphilis D013587 6 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Syphilis, Latent D013592 4 associated lipids
Tachycardia D013610 7 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Thromboembolism D013923 6 associated lipids
Thyroid Crisis D013958 1 associated lipids
Onychomycosis D014009 2 associated lipids
Tooth Diseases D014076 2 associated lipids
Tooth Fractures D014082 2 associated lipids
Tooth, Impacted D014095 9 associated lipids
Toothache D014098 3 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Tremor D014202 15 associated lipids
Trench Fever D014205 1 associated lipids
Trisomy D014314 6 associated lipids
Tuberculosis D014376 20 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Typhus, Endemic Flea-Borne D014437 3 associated lipids
Typhus, Epidemic Louse-Borne D014438 1 associated lipids
Uremia D014511 33 associated lipids
Urethral Diseases D014522 4 associated lipids
Urethritis D014526 9 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Urticaria D014581 13 associated lipids
Uveitis D014605 14 associated lipids
Varicose Ulcer D014647 4 associated lipids
Vibrio Infections D014735 5 associated lipids
Vomiting D014839 21 associated lipids
Vulvovaginitis D014848 2 associated lipids
Whooping Cough D014917 6 associated lipids
Wound Infection D014946 12 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Xerostomia D014987 6 associated lipids
Yaws D015001 4 associated lipids
Superinfection D015163 3 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Scleritis D015423 3 associated lipids
Weight Gain D015430 101 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Torsades de Pointes D016171 2 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Bacteremia D016470 9 associated lipids
Foot Ulcer D016523 4 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Critical Illness D016638 13 associated lipids
Empyema, Pleural D016724 2 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ehrlichiosis D016873 2 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Chalazion D017043 1 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Krokidis MG et al. Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis. 2014 Antimicrob. Agents Chemother. pmid:24189263
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Sadeghi J and Mansouri S Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman). 2014 APMIS pmid:24033803
Wang J et al. Association of osteopontin polymorphisms with nasopharyngeal carcinoma risk. 2014 Hum. Immunol. pmid:24120738
Cetecioglu Z Aerobic inhibition assessment for anaerobic treatment effluent of antibiotic production wastewater. 2014 Environ Sci Pollut Res Int pmid:24146324
Gustafsson F et al. A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. 2014 Toxicol. Sci. pmid:24085192
Haworth CS et al. Long-term macrolide maintenance therapy in non-CF bronchiectasis: evidence and questions. 2014 Respir Med pmid:25301290
Nikolay R et al. Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli. 2014 Nucleic Acids Res. pmid:24792169
Sanamrad A et al. Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid. 2014 Proc. Natl. Acad. Sci. U.S.A. pmid:25056965
Shim J et al. Clinical inquiry: what is the best treatment for impetigo ? 2014 J Fam Pract pmid:25061625
Krishnappa LG et al. Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. 2014 Acta Microbiol Immunol Hung pmid:24939685
Florindo C et al. Epidemiological surveillance of colonising group B Streptococcus epidemiology in the Lisbon and Tagus Valley regions, Portugal (2005 to 2012): emergence of a new epidemic type IV/clonal complex 17 clone. 2014 Euro Surveill. pmid:24957747
Ye C et al. Correlation between AcrB trimer association affinity and efflux activity. 2014 Biochemistry pmid:24854514
Zhang XF et al. Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy? 2014 Medicine (Baltimore) pmid:25101987
Pierson RC et al. A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. 2014 Obstet Gynecol pmid:25162251
Barbosa TM et al. A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. 2014 PLoS ONE pmid:25548909
Källén B and Danielsson BR Fetal safety of erythromycin. An update of Swedish data. 2014 Eur. J. Clin. Pharmacol. pmid:24352632
Rozov-Ung I et al. Detection of drug effects on gastric emptying and contractility using a wireless motility capsule. 2014 BMC Gastroenterol pmid:24383478
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Sugamata R et al. Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. 2014 J. Antibiot. pmid:24496145
Pasquini L et al. Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. 2014 Sci. Total Environ. pmid:24631609
Fröhlicher S et al. Serotype distribution and antimicrobial susceptibility of group B streptococci in pregnant women: results from a Swiss tertiary centre. 2014 Swiss Med Wkly pmid:24652673
Žemličková H et al. [Resistance monitoring working group: resistance to erythromycin, ciprofloxacin, and tetracycline in human isolates of Campylobacter spp. in the Czech Republic tested by the EUCAST standard method]. 2014 Epidemiol Mikrobiol Imunol pmid:25412481
Cai HL et al. Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. 2014 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:24424301
Arêas GP et al. Antimicrobial susceptibility patterns, emm type distribution and genetic diversity of Streptococcus pyogenes recovered in Brazil. 2014 Mem. Inst. Oswaldo Cruz pmid:25410998
Khannous L et al. Isolation of a novel amylase and lipase-producing Pseudomonas luteola strain: study of amylase production conditions. 2014 Lipids Health Dis pmid:24405763
Wang J et al. [Drug susceptibility and homologous analysis on Corynebacterium striatum strains isolated from inpatients]. 2014 Zhonghua Yi Xue Za Zhi pmid:25410920
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Wu H et al. Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea. 2014 Microb. Cell Fact. pmid:25391994
Leirós M et al. Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. 2014 ACS Chem Neurosci pmid:24219236
Caierão J et al. Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. 2014 PLoS ONE pmid:25356595
Arenz S et al. Drug sensing by the ribosome induces translational arrest via active site perturbation. 2014 Mol. Cell pmid:25306253
Belén Flórez A et al. Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. 2014 Biomed Res Int pmid:25302306
Farley R et al. Antibiotics for bronchiolitis in children under two years of age. 2014 Cochrane Database Syst Rev pmid:25300167
Farabella I et al. Allosteric signalling in the outer membrane translocation domain of PapC usher. 2014 Elife pmid:25271373
Jaiswal N et al. Distribution of serotypes, vaccine coverage, and antimicrobial susceptibility pattern of Streptococcus pneumoniae in children living in SAARC countries: a systematic review. 2014 PLoS ONE pmid:25268974
Badri T et al. [Erythrasma: study of 16 cases]. 2014 Tunis Med pmid:25224418
Dörries K et al. Impact of antibiotics with various target sites on the metabolome of Staphylococcus aureus. 2014 Antimicrob. Agents Chemother. pmid:25224006
Labbeiki G et al. Enhanced oxygen transfer rate and bioprocess yield by using magnetite nanoparticles in fermentation media of erythromycin. 2014 Daru pmid:25223458
Bharucha AE et al. A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography. 2014 Eur J Radiol pmid:25217123
Johnson SR et al. In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins. 2014 Antimicrob. Agents Chemother. pmid:25199775
Kara M et al. Expression changes of antioxidant, apoptotic, anti-apoptotic genes and miR-15b-34a-21-98 in over tissue by using erythromycin, quinacrine and tetracycline in non-surgical sterilization. 2014 Mol. Biol. Rep. pmid:25195052
Shera IA et al. Unusual case of Hashimoto's encephalopathy and pseudo-obstruction in a patient with undiagnosed hypothyroidism: a case report. 2014 J Med Case Rep pmid:25194644
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Kemp MW et al. Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. 2014 Am. J. Obstet. Gynecol. pmid:24589547
Carls A et al. Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. 2014 Br J Clin Pharmacol pmid:25139487
Zhang Y et al. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721407
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Shen Y et al. Mitigative effect of erythromycin on PMMA challenged preosteoblastic MC3T3-E1 cells. 2014 ScientificWorldJournal pmid:25110723
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Ramos V et al. [Mobile genetic elements associated with erythromycin-resistant isolates of Streptococcus pneumoniae in Colombia]. 2014 Biomedica pmid:24968052
Moore KT et al. An open-label study to estimate the effect of steady-state erythromycin on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban in subjects with renal impairment and normal renal function. 2014 J Clin Pharmacol pmid:24964176
Montilla A et al. Genetic environment of the lnu(B) gene in a Streptococcus agalactiae clinical isolate. 2014 Antimicrob. Agents Chemother. pmid:24957835
Komiya K et al. Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. 2014 Int. J. Antimicrob. Agents pmid:24948577
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Crumb WJ Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. 2014 Br. J. Pharmacol. pmid:24417241
Luan R et al. [Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis]. 2014 Zhonghua Wei Zhong Bing Ji Jiu Yi Xue pmid:24912643
Liu J et al. Tissue distribution, bioconcentration, metabolism, and effects of erythromycin in crucian carp (Carassius auratus). 2014 Sci. Total Environ. pmid:24911771
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Wang Z et al. High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. 2014 Clin. Microbiol. Infect. pmid:24816168
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de las Heras MN Linear IgA bullous dermatosis of childhood: good response to antibiotic treatment. 2014 Clin. Exp. Dermatol. pmid:24772486
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Calvert H et al. Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer. 2014 Anticancer Drugs pmid:24637575
Janoir C et al. Clonal expansion of the macrolide resistant ST386 within pneumococcal serotype 6C in France. 2014 PLoS ONE pmid:24603763
Melnik BC The P450 system and mTORC1 signalling in acne. 2014 Exp. Dermatol. pmid:24588627
Xiao C et al. Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. 2014 J Perinat Med pmid:24566358
Montes M et al. What causes decreased erythromycin resistance in Streptococcus pyogenes? Dynamics of four clones in a southern European region from 2005 to 2012. 2014 J. Antimicrob. Chemother. pmid:24562616
Benito D et al. Genetic lineages, antimicrobial resistance, and virulence in Staphylococcus aureus of meat samples in Spain: analysis of immune evasion cluster (IEC) genes. 2014 Foodborne Pathog. Dis. pmid:24479575
Boomkamp SD et al. Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. 2014 Br. J. Pharmacol. pmid:24467222
Jun BY et al. Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. 2014 Surg Endosc pmid:24380989
Ren WP et al. Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. 2014 J. Biomed. Mater. Res. Part B Appl. Biomater. pmid:24347324
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Lu WC et al. Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. 2014 Neurol. Sci. pmid:24277204
Thumu SC and Halami PM Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food. 2014 J. Appl. Microbiol. pmid:24206069
Lu B et al. Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China. 2014 Clin. Microbiol. Infect. pmid:24118553
Zheng PX et al. Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. 2014 Clin. Microbiol. Infect. pmid:24118239
Singh P et al. Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. 2014 Fundam Clin Pharmacol pmid:24117516
Dalbøge CS et al. Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. 2014 J. Cyst. Fibros. pmid:24035278
Csikó G et al. Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. 2014 J. Vet. Pharmacol. Ther. pmid:24628435
Rodríguez-Gutiérrez R et al. Herpes zoster ophthalmicus masked by hymenoptera stings. 2014 Am. J. Med. Sci. pmid:23085675
Aydin S et al. Performance of anaerobic sequencing batch reactor in the treatment of pharmaceutical wastewater containing erythromycin and sulfamethoxazole mixture. 2014 Water Sci. Technol. pmid:25429450