erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Riippi M et al. | The effect of compression force on surface structure, crushing strength, friability and disintegration time of erythromycin acistrate tablets. | 1998 | Eur J Pharm Biopharm | pmid:9885307 |
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Manna PK and Basu SK | Preparation and evaluation of erythromycin fumarate--a new derivative of erythromycin. | 1998 | Drug Dev Ind Pharm | pmid:9876541 |
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Roy SK et al. | A randomized clinical trial to compare the efficacy of erythromycin, ampicillin and tetracycline for the treatment of cholera in children. | 1998 Jul-Aug | Trans. R. Soc. Trop. Med. Hyg. | pmid:9850410 |
Yamazaki H and Shimada T | Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes. | 1998 | Xenobiotica | pmid:9849646 |
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Soriano F et al. | In-vitro antimicrobial activity of HMR 3004 (RU 64004) against erythromycin A-sensitive and -resistant Corynebacterium spp. isolated from clinical specimens. | 1998 | J. Antimicrob. Chemother. | pmid:9848450 |
Johnson AP et al. | In-vitro activity of sanfetrinem against isolates of Streptococcus pneumoniae and Staphylococcus aureus. | 1998 | J. Antimicrob. Chemother. | pmid:9848449 |
Shadomy S et al. | Josamycin and rosamicin: in vitro comparisons with erythromycin and clindamycin. | 1976 | Antimicrob. Agents Chemother. | pmid:984811 |
Strausbaugh LJ et al. | Comparative pharmacology of josamycin and erythromycin stearate. | 1976 | Antimicrob. Agents Chemother. | pmid:984786 |
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Baltch AL et al. | Antibacterial effects of levofloxacin, erythromycin, and rifampin in a human monocyte system against Legionella pneumophila. | 1998 | Antimicrob. Agents Chemother. | pmid:9835507 |
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