erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Bronchial Hyperreactivity D016535 15 associated lipids
Foot Ulcer D016523 4 associated lipids
Bacteremia D016470 9 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Torsades de Pointes D016171 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Weight Gain D015430 101 associated lipids
Scleritis D015423 3 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Superinfection D015163 3 associated lipids
Yaws D015001 4 associated lipids
Xerostomia D014987 6 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Wound Infection D014946 12 associated lipids
Whooping Cough D014917 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Xu J et al. [Prognosticating the region-selectivity in the O-methylation reaction of erythromycins by conformational search model]. 2003 Yao Xue Xue Bao pmid:12778744
Sun W et al. [Glycosyl isomerization based on the biosynthesis of natural-product sugar from microorganism]. 2013 Yao Xue Xue Bao pmid:23672013
Watanabe Y et al. [Relationship between quality and serum level after the oral administration of commercial erythromycin tablets in man (author's transl)]. 1977 Yakugaku Zasshi pmid:911413
Matsuoka M [Study of macrolide, lincosamide, and streptogramin B antibiotics resistance in Staphylococcus aureus]. 2000 Yakugaku Zasshi pmid:10774259
Nakamura H et al. Effect of particle size on mixing degree in dispensation. 2004 Yakugaku Zasshi pmid:15049131
Nakamura H et al. Effect of mixing method on the mixing degree during the preparation of triturations. 2004 Yakugaku Zasshi pmid:15049130
Watanabe Y et al. [Effect of dissolving pH of enteric coating agent on bioavailability of enteric coated tablets of erythromycin in man (author's transl)]. 1978 Yakugaku Zasshi pmid:30834
Miyazaki M et al. [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. 2014 Yakugaku Zasshi pmid:24492229
Otsuka M et al. [Studies on fungicides. XIV. Effect of erythromycin on the growth of fungal mycelia (author's transl)]. 1978 Yakugaku Zasshi pmid:566318
Zhang Y et al. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721407
Ung D et al. Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis. 2009 Xenobiotica pmid:19575604
Salimi A et al. Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. 2016 Xenobiotica pmid:26068526
Emoto C et al. Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human. 2001 Xenobiotica pmid:11491388
Pasic J et al. The interaction between chronic oral slow-release theophylline and single-dose intravenous erythromycin. 1987 Xenobiotica pmid:3604256
Ward KW et al. Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human. 2005 Xenobiotica pmid:16019946
Molnari JC and Myers AL Carbonyl reduction of bupropion in human liver. 2012 Xenobiotica pmid:22339467
Kaye B and Roberts DW The metabolism of oxamniquine in the gut wall. 1980 Xenobiotica pmid:7395269
Watanabe M et al. Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo. 1999 Xenobiotica pmid:10553724
Trepanier LA and Miller JL NADH-dependent reduction of sulphamethoxazole hydroxylamine in dog and human liver microsomes. 2000 Xenobiotica pmid:11307968
Kanazu T et al. Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. I: evaluation of cynomolgus monkeys as surrogates for humans. 2004 Xenobiotica pmid:15370956