erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kearney JA et al. | In vitro activities of the oxazolidinone compounds linezolid (PNU-100766) and eperzolid (PNU-100592) against middle ear isolates of Streptococcus pneumoniae. | 1999 | Int. J. Antimicrob. Agents | pmid:10418759 |
de Sousa G et al. | A multi-laboratory evaluation of cryopreserved monkey hepatocyte functions for use in pharmaco-toxicology. | 1999 | Chem. Biol. Interact. | pmid:10418972 |
Latorre G et al. | [Chlamydia pneumoniae pneumonia]. | 1998 Jan-Mar | Rev Med Univ Navarra | pmid:10420952 |
Cvetkovic M et al. | OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. | 1999 | Drug Metab. Dispos. | pmid:10421612 |
Okada J et al. | [Changes of antimicrobial susceptibility of anaerobic bacteria from clinical specimens (author's transl)]. | 1975 | Jpn J Antibiot | pmid:1042183 |
Bachmann K et al. | A study of the interaction between dirithromycin and astemizole in healthy adults. | 1997 Feb-Mar | Am J Ther | pmid:10423595 |
Callréus T et al. | Changes in gastrointestinal motility influence the absorption of desmopressin. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10424324 |
Johnson MM et al. | Effect of carbon dioxide on testing of susceptibilities of respiratory tract pathogens to macrolide and azalide antimicrobial agents. | 1999 | Antimicrob. Agents Chemother. | pmid:10428903 |
Giovanetti E et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains. | 1999 | Antimicrob. Agents Chemother. | pmid:10428916 |
Credito KL et al. | Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. | 1999 | Antimicrob. Agents Chemother. | pmid:10428930 |