erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Krecic-Shepard ME et al. | In vivo comparison of putative probes of CYP3A4/5 activity: erythromycin, dextromethorphan, and verapamil. | 1999 | Clin. Pharmacol. Ther. | pmid:10430108 |
Barone A et al. | Microbiotica associated with refractory periodontis. Prevalence and antibiotic susceptibility. | 1999 | Minerva Stomatol | pmid:10434536 |
Kumar A and Will EJ | Necrotizing fasciitis and Legionnaires' disease after combined renal and pancreatic transplantation: a penalty of overseas travel. | 1999 | Nephrol. Dial. Transplant. | pmid:10435897 |
Drug interactions. | 1999 | Med Lett Drugs Ther | pmid:10436770 | |
Sakai C et al. | Nocardia asteroides pneumonia, subcutaneous abscess and meningitis in a patient with advanced malignant lymphoma: successful treatment based on in vitro antimicrobial susceptibility. | 1999 | Intern. Med. | pmid:10440509 |
Kearney GC et al. | Structural elucidation studies of erythromycins by electrospray tandem mass spectrometry II. | 1999 | Rapid Commun. Mass Spectrom. | pmid:10440983 |
Blackwell BA et al. | Oxidative deamination of hydrolyzed fumonisin B(1) (AP(1)) by cultures of Exophiala spinifera. | 1999 | Nat. Toxins | pmid:10441035 |
Albini E et al. | Activity of aerosol thiamphenicol glycinate acetylcysteinate in a mouse model of S. pyogenes pneumonia. | 1999 | Arzneimittelforschung | pmid:10442213 |
Limia A et al. | Five-year analysis of antimicrobial susceptibility of the Streptococcus milleri group. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10442424 |
Schiano P et al. | [Gastroparesis of central origin: usefulness of erythromycin]. | 1999 | Can J Anaesth | pmid:10442972 |