erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stellato TA et al. | Antibiotics in elective colon surgery. A randomized trial of oral, systemic, and oral/systemic antibiotics for prophylaxis. | 1990 | Am Surg | pmid:2194417 |
Hoffman E | Prophylactic antibiotic usage in clean surgical procedures. | 1984 | Am Surg | pmid:6703529 |
PARROTT FD et al. | Staphylococcal bacteremia: report of a case successfully treated with erythromycin. | 1954 | Am Pract Dig Treat | pmid:13171526 |
FLIPPIN HF and FOLTZ EL | The newer antimicrobial agents. | 1953 | Am Pract Dig Treat | pmid:13080581 |
PELNER L and PUDERBACH W | Pseudomembranous staphylococcal enterocolitis: recovery in two patients treated with erythromycin; some notes on antibiotic resistance. | 1956 | Am Pract Dig Treat | pmid:13362857 |
Ciummo PE and Katz NL | Interactions and drug-metabolizing enzymes. | 1995 | Am Pharm | pmid:7484817 |
Mullan PA | Rand Corporation issues PPI study findings. | 1981 | Am Pharm | pmid:7340488 |
Miller SD | Madura foot: treatment of Nocardia nova infection with antibiotics alone. | 2001 | Am J. Orthop. | pmid:11411876 |
Bachmann K et al. | A study of the interaction between dirithromycin and astemizole in healthy adults. | 1997 Feb-Mar | Am J Ther | pmid:10423595 |
Cvetanovic I et al. | The differential antibacterial and gastrointestinal effects of erythromycin and its chiral isolates. | 2006 Jan-Feb | Am J Ther | pmid:16428922 |
Sikri V et al. | Cotransport of macrolide and fluoroquinolones, a beneficial interaction reversing P-glycoprotein efflux. | 2004 Nov-Dec | Am J Ther | pmid:15543082 |
RUBIN A et al. | The effects of the administration of erythromycin upon Neisseria gonorrhoeae and pleuropneumonia-like organisms in the uterine cervix. | 1954 | Am J Syph Gonorrhea Vener Dis | pmid:13189043 |
GABLE GR et al. | Treatment of gonorrhea with erythromycin. | 1953 | Am J Syph Gonorrhea Vener Dis | pmid:13065617 |
ALEXANDER LJ and SCHOCH AG | Erythromycin in venereal diseases. | 1954 | Am J Syph Gonorrhea Vener Dis | pmid:13138815 |
MANNING PR et al. | Erythromycin in the treatment of gonorrhea. | 1954 | Am J Syph Gonorrhea Vener Dis | pmid:13138816 |
Park HH et al. | The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. | 2010 Sep-Oct | Am J Rhinol Allergy | pmid:21244734 |
Jiang RS et al. | Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. | 2012 Jul-Aug | Am J Rhinol Allergy | pmid:22801017 |
Fox KK et al. | Gonorrhea in the HIV era: a reversal in trends among men who have sex with men. | 2001 | Am J Public Health | pmid:11392941 |
Tsevat J et al. | Cost-effectiveness of antibiotic prophylaxis for dental procedures in patients with artificial joints. | 1989 | Am J Public Health | pmid:2499200 |
Usiskin SI et al. | Retreatment with clozapine after erythromycin-induced neutropenia. | 2000 | Am J Psychiatry | pmid:10831491 |
Funderburg LG et al. | Seizure following addition of erythromycin to clozapine treatment. | 1994 | Am J Psychiatry | pmid:7977898 |
Crum NF et al. | Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. | 2003 | Am J Prev Med | pmid:12880877 |
Ghidini A et al. | Successful outcome after antibiotic treatment of postamniocentesis membrane rupture and chorioamnionitis in multiple pregnancy. | 1999 | Am J Perinatol | pmid:10772199 |
Bar J et al. | Effect of antibiotic therapy in preterm premature rupture of the membranes on neonatal mortality and morbidity. | 2000 | Am J Perinatol | pmid:11110340 |
Ogasawara KK and Goodwin TM | The efficacy of prophylactic erythromycin in preventing vertical transmission of Ureaplasma urealyticum. | 1997 | Am J Perinatol | pmid:9259934 |
El Younis CM et al. | Rapid marked response of severe hyperemesis gravidarum to oral erythromycin. | 1998 | Am J Perinatol | pmid:9890250 |
Kyrmizakis DE et al. | QT prolongation and torsades de pointes associated with concurrent use of cisapride and erythromycin. | 2002 Sep-Oct | Am J Otolaryngol | pmid:12239699 |
Koegel L | Ototoxicity: a contemporary review of aminoglycosides, loop diuretics, acetylsalicylic acid, quinine, erythromycin, and cisplatinum. | 1985 | Am J Otol | pmid:3872601 |
Sacristán JA et al. | Ototoxicity of erythromycin in man: electrophysiologic approach. | 1993 | Am J Otol | pmid:8503495 |
Lilley LL and Guanci R | Drug interaction triggers weakness. | 1998 | Am J Nurs | pmid:9556673 |
New antibiotics look good against M. avium. | 1992 | Am J Nurs | pmid:1309625 | |
Devereux PM and Goldstein EJ | Legionnaires' disease: finding answers to the riddle. | 1980 | Am J Nurs | pmid:6898101 |
Erythromycin use linked to pyloric stenosis. | 2000 | Am J Nurs | pmid:10738394 | |
Lee WS | Disc sentitivity as a diagnostic aid in the identification of group D enterococci. | 1972 | Am J Med Technol | pmid:4490310 |
Hansen JL and Swanson LN | Case study: Drug interference in clinical chemistry. | 1981 | Am J Med Technol | pmid:7223765 |
Bauer AW | The decline of antibiotic resistance of Staphylococcus aureus isolated in the community. | 1971 | Am J Med Technol | pmid:5206836 |
Dietz CC et al. | Double-gradient plate susceptibility testing of an Enterococcus and its L-form. | 1973 | Am J Med Technol | pmid:4701052 |
WEISS E and DRESSLER HR | Selection of an erythromycin-resistant strain of Rickettsia prowazekii. | 1960 | Am J Hyg | pmid:13843711 |
David LM | Phlebitis with intravenous erythromycin. | 1987 | Am J Hosp Pharm | pmid:3578303 |
Pluta PL and Morgan PK | Stability of erythromycin in intravenous admixtures. | 1986 | Am J Hosp Pharm | pmid:3799601 |
Meade RH | Drug therapy reviews: antimicrobial spectrum, pharmacology and therapeutic use of erythromycin and its derivatives. | 1979 | Am J Hosp Pharm | pmid:386785 |
Pinchiera JC et al. | Effect of bariatric surgery on erythromycin absorption. | 1981 | Am J Hosp Pharm | pmid:7211889 |
Dombrower P | Intravenous erythromycin dosages. | 1979 | Am J Hosp Pharm | pmid:525638 |
Williams KG | Pharmacists' duty to warn of drug interactions. Dooley v. Everett. | 1992 | Am J Hosp Pharm | pmid:1471651 |
Garrison TJ and Kleinschmidt M | Other views on erythromycin selection. | 1981 | Am J Hosp Pharm | pmid:7258211 |
Kistler SB and Kough RH | Antibiotic acquistions in a 387-bed general hospital during 1960, 1965, 1967 and 1968. | 1969 | Am J Hosp Pharm | pmid:4313068 |
Higgin CR and Mazur MS | Prepacking unit dose erythromycin ophthalmic ointment. | 1984 | Am J Hosp Pharm | pmid:6465146 |
Bergstrom RF and Fites AL | Letter: Stability of erythromycin gluceptate in sodium chloride injection and dextrose injection. | 1975 | Am J Hosp Pharm | pmid:237418 |
LeBel M | Risk-benefit equation for erythromycin estolate. | 1980 | Am J Hosp Pharm | pmid:7361788 |
O'Brien TE | Excretion of drugs in human milk. | 1974 | Am J Hosp Pharm | pmid:4608122 |