erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cook M and Lynch WH | A sensitive nested reverse transcriptase PCR assay to detect viable cells of the fish pathogen Renibacterium salmoninarum in Atlantic salmon (Salmo salar L.). | 1999 | Appl. Environ. Microbiol. | pmid:10388701 |
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Mazzei T et al. | Pharmacokinetics of dirithromycin in patients with mild or moderate cirrhosis. | 1999 | Antimicrob. Agents Chemother. | pmid:10390202 |
Kawanami R et al. | [Successful treatment of allergic bronchopulmonary aspergillosis with erythromycin and fluconazole]. | 1999 | Nihon Kokyuki Gakkai Zasshi | pmid:10390974 |
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Classen DC et al. | Clinical and financial impact of intravenous erythromycin therapy in hospitalized patients. | 1999 | Ann Pharmacother | pmid:10410176 |
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Messini M et al. | Bacteremia after dental treatment in mentally handicapped people. | 1999 | J. Clin. Periodontol. | pmid:10412852 |
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Lin CF and Chung TC | Cloning of erythromycin-resistance determinants and replication origins from indigenous plasmids of Lactobacillus reuteri for potential use in construction of cloning vectors. | 1999 | Plasmid | pmid:10413663 |
Driessen JH | A computer study of bacterial resistance patterns to antibiotics. | 1975 | Chemotherapy | pmid:1041490 |
Finegold SM | Antimicrobial therapy of anaerobic infections. | 1975 | Postgrad Med | pmid:1041514 |
Matsumoto H et al. | Sensitivity of fresh isolates of Haemophilus to current antibiotics. | 1975 | Jpn J Antibiot | pmid:1041598 |
Lee DO and Lee CD | Serotonin syndrome in a child associated with erythromycin and sertraline. | 1999 | Pharmacotherapy | pmid:10417041 |
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Cvetkovic M et al. | OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. | 1999 | Drug Metab. Dispos. | pmid:10421612 |
Okada J et al. | [Changes of antimicrobial susceptibility of anaerobic bacteria from clinical specimens (author's transl)]. | 1975 | Jpn J Antibiot | pmid:1042183 |
Bachmann K et al. | A study of the interaction between dirithromycin and astemizole in healthy adults. | 1997 Feb-Mar | Am J Ther | pmid:10423595 |
Callréus T et al. | Changes in gastrointestinal motility influence the absorption of desmopressin. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10424324 |
Johnson MM et al. | Effect of carbon dioxide on testing of susceptibilities of respiratory tract pathogens to macrolide and azalide antimicrobial agents. | 1999 | Antimicrob. Agents Chemother. | pmid:10428903 |
Giovanetti E et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains. | 1999 | Antimicrob. Agents Chemother. | pmid:10428916 |
Credito KL et al. | Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. | 1999 | Antimicrob. Agents Chemother. | pmid:10428930 |
Krecic-Shepard ME et al. | In vivo comparison of putative probes of CYP3A4/5 activity: erythromycin, dextromethorphan, and verapamil. | 1999 | Clin. Pharmacol. Ther. | pmid:10430108 |
Barone A et al. | Microbiotica associated with refractory periodontis. Prevalence and antibiotic susceptibility. | 1999 | Minerva Stomatol | pmid:10434536 |
Kumar A and Will EJ | Necrotizing fasciitis and Legionnaires' disease after combined renal and pancreatic transplantation: a penalty of overseas travel. | 1999 | Nephrol. Dial. Transplant. | pmid:10435897 |
Drug interactions. | 1999 | Med Lett Drugs Ther | pmid:10436770 | |
Sakai C et al. | Nocardia asteroides pneumonia, subcutaneous abscess and meningitis in a patient with advanced malignant lymphoma: successful treatment based on in vitro antimicrobial susceptibility. | 1999 | Intern. Med. | pmid:10440509 |
Kearney GC et al. | Structural elucidation studies of erythromycins by electrospray tandem mass spectrometry II. | 1999 | Rapid Commun. Mass Spectrom. | pmid:10440983 |
Blackwell BA et al. | Oxidative deamination of hydrolyzed fumonisin B(1) (AP(1)) by cultures of Exophiala spinifera. | 1999 | Nat. Toxins | pmid:10441035 |
Albini E et al. | Activity of aerosol thiamphenicol glycinate acetylcysteinate in a mouse model of S. pyogenes pneumonia. | 1999 | Arzneimittelforschung | pmid:10442213 |
Limia A et al. | Five-year analysis of antimicrobial susceptibility of the Streptococcus milleri group. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10442424 |
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Moss AJ et al. | A review of the cardiac systemic side-effects of antihistamines: ebastine. | 1999 | Clin. Exp. Allergy | pmid:10444238 |
Jones KL et al. | The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. | 1999 | Am. J. Gastroenterol. | pmid:10445530 |
Vorland LH et al. | Interference of the antimicrobial peptide lactoferricin B with the action of various antibiotics against Escherichia coli and Staphylococcus aureus. | 1999 | Scand. J. Infect. Dis. | pmid:10447328 |
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Wang H et al. | Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro. | 1999 | Zhongguo Yao Li Xue Bao | pmid:10452125 |
Tamaoki J et al. | Macrolide antibiotics protect against immune complex-induced lung injury in rats: role of nitric oxide from alveolar macrophages. | 1999 | J. Immunol. | pmid:10453038 |
Morales WJ et al. | Change in antibiotic resistance of group B streptococcus: impact on intrapartum management. | 1999 | Am. J. Obstet. Gynecol. | pmid:10454674 |
Grunt J and Krcméry V | Multiple drug-resistance in staphylococci, an analysis of all-nation computer-processed data. | 1976 | Zentralbl Bakteriol Orig A | pmid:1045837 |
Watanakunakorn C | Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. | 1976 | Am. J. Med. | pmid:1045861 |
Boyanova L et al. | Characteristics and trends in macrolide resistance among Helicobacter pylori strains isolated in Bulgaria over four years. | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10459482 |