erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Jones TR et al. | Efficacy of an antibiotic mouthwash in contaminated head and neck surgery. | 1989 | Am. J. Surg. | pmid:2802036 |
Brass C et al. | The effect of metronidazole on the incidence of postoperative wound infection in elective colon surgery. | 1978 | Am. J. Surg. | pmid:341733 |
LeVeen HH et al. | Effects of prophylactic antibiotics on colonic healing. | 1976 | Am. J. Surg. | pmid:1247153 |
Carlson RG et al. | Erythromycin enhances delayed gastric emptying in dogs after Roux-Y antrectomy. | 1991 | Am. J. Surg. | pmid:1987856 |
Nissan A et al. | Direct inhibitory effect of erythromycin on human alimentary tract smooth muscle. | 2002 | Am. J. Surg. | pmid:11975929 |
Dillon ML and Bowling KA | Effect of antibiotics on wound and stool cultures. Comparison of intravenous terramycin with other antibiotics. | 1967 | Am. J. Surg. | pmid:5334435 |
Nakabayashi T et al. | Gastropyloric motor activity and the effects of erythromycin given orally after esophagectomy. | 2002 | Am. J. Surg. | pmid:11943134 |
COHN I and LONGACRE AB | Erythromycin and erythromycin-neomycin for intestinal antisepsis. | 1957 | Am. J. Surg. | pmid:13458603 |
Tzovaras G et al. | The effect of intravenous erythromycin on esophageal motility in healthy subjects. | 1996 | Am. J. Surg. | pmid:8615464 |
Gombert ME et al. | Cavitary Legionnaires' pneumonia: nosocomial infection in renal transplant recipients. | 1984 | Am. J. Surg. | pmid:6367506 |
Marshall W et al. | Legionnaires' disease in renal transplant patients. | 1981 | Am. J. Surg. | pmid:7013509 |
Pennathur A et al. | Erythromycin strengthens the defective lower esophageal sphincter in patients with gastroesophageal reflux disease. | 1994 | Am. J. Surg. | pmid:8311129 |
Fry DE | Colon preparation and surgical site infection. | 2011 | Am. J. Surg. | pmid:21429471 |
Weaver M et al. | Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery. | 1986 | Am. J. Surg. | pmid:3083705 |
Baciewicz AM and Baciewicz FA | Cyclosporine pharmacokinetic drug interactions. | 1989 | Am. J. Surg. | pmid:2644865 |
EICHENWALD HF and SHINEFIELD HR | RATIONAL USE OF ANTIBIOTICS. | 1964 | Am. J. Surg. | pmid:14129331 |
Condon RE et al. | Oral neomycin and erythromycin compared with single-dose systemic metronidazole and ceftriaxone prophylaxis in elective colorectal surgery. | 1986 | Am. J. Surg. | pmid:3777340 |
Vanaudenaerde BM et al. | Macrolides inhibit IL17-induced IL8 and 8-isoprostane release from human airway smooth muscle cells. | 2007 | Am. J. Transplant. | pmid:17061983 |
JUNG RC et al. | Fumagillin and erythromycin in the treatment of amebiasis. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13268803 |
MCHARDY G et al. | Erythromycin in amebiasis. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13268804 |
NELSON TL et al. | Amebic hepatitis; laboratory findings and treatment with erythromycin. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13259005 |
Hamel MJ et al. | Efficacy of trimethoprim-sulfamethoxazole compared with sulfadoxine-pyrimethamine plus erythromycin for the treatment of uncomplicated malaria in children with integrated management of childhood illness dual classifications of malaria and pneumonia. | 2005 | Am. J. Trop. Med. Hyg. | pmid:16172491 |
NOR EL-DIN G | Erythromycin in the treatment of amebiasis. | 1956 | Am. J. Trop. Med. Hyg. | pmid:13292653 |
Gingras BA and Jensen JB | Activity of azithromycin (CP-62,993) and erythromycin against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro. | 1992 | Am. J. Trop. Med. Hyg. | pmid:1326232 |
Robins-Browne RM et al. | Treatment of acute nonspecific gastroenteritis of infants and young children with erythromycin. | 1983 | Am. J. Trop. Med. Hyg. | pmid:6349401 |
WILMOT AJ et al. | Erythromycin in amebic liver abscess. | 1958 | Am. J. Trop. Med. Hyg. | pmid:13595213 |
ANDERSON HH et al. | Erythromycin stearate against systemic amebiasis in Colombia. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13238724 |
VILLAREJOS VM | Treatment of amebiasis with erythromycin. | 1955 | Am. J. Trop. Med. Hyg. | pmid:13238725 |
Kelly DJ et al. | Rickettsia tsutsugamushi infection in cell culture: antibiotic susceptibility determined by flow cytometry. | 1995 | Am. J. Trop. Med. Hyg. | pmid:8561261 |
ANDERSON HH et al. | Antibiotic synergism in amebiasis. | 1954 | Am. J. Trop. Med. Hyg. | pmid:13138827 |
Hall KA et al. | Characterization of counterfeit artesunate antimalarial tablets from southeast Asia. | 2006 | Am. J. Trop. Med. Hyg. | pmid:17123969 |
Gingras BA and Jensen JB | Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. | 1993 | Am. J. Trop. Med. Hyg. | pmid:8394660 |
MCCOWEN MC et al. | The effects of erythromycin (ilotycin, lilly) against certain parasitic organisms. | 1953 | Am. J. Trop. Med. Hyg. | pmid:13040654 |
Crawford KA et al. | Efficacy of amoscanate against experimental schistosomal infections in monkeys. | 1983 | Am. J. Trop. Med. Hyg. | pmid:6625061 |
Perine PL and Teklu B | Antibiotic treatment of louse-borne relapsing fever in Ethiopia: a report of 377 cases. | 1983 | Am. J. Trop. Med. Hyg. | pmid:6625065 |
Nieto JE et al. | In vitro effects of erythromycin, lidocaine, and metoclopramide on smooth muscle from the pyloric antrum, proximal portion of the duodenum, and middle portion of the jejunum of horses. | 2000 | Am. J. Vet. Res. | pmid:10772106 |
Roussel AJ et al. | Prokinetic effects of erythromycin on the ileum, cecum, and pelvic flexure of horses during the postoperative period. | 2000 | Am. J. Vet. Res. | pmid:10772107 |
Fox JG et al. | Ferret as a potential reservoir for human campylobacteriosis. | 1983 | Am. J. Vet. Res. | pmid:6870007 |
Clarke CR et al. | Response of Pasteurella haemolytica to erythromycin and dexamethasone in calves with established infection. | 1992 | Am. J. Vet. Res. | pmid:1524293 |
Burrows GE | Effects of experimentally induced Pasteurella haemolytica pneumonia on the pharmacokinetics of erythromycin in the calf. | 1985 | Am. J. Vet. Res. | pmid:4014829 |
Garner HE and Coles EH | Staphylococcus aureus of canine origin: bacteriophage typing and antibiotic sensitivity of cultures isolated from the nostril. | 1965 | Am. J. Vet. Res. | pmid:5882553 |
Lester GD et al. | Effect of erythromycin lactobionate on myoelectric activity of ileum, cecum, and right ventral colon, and cecal emptying of radiolabeled markers in clinically normal ponies. | 1998 | Am. J. Vet. Res. | pmid:9522953 |
Regnery RL et al. | Experimentally induced Bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats. | 1996 | Am. J. Vet. Res. | pmid:8950424 |
Ringger NC et al. | Effect of bethanechol or erythromycin on gastric emptying in horses. | 1996 | Am. J. Vet. Res. | pmid:8950433 |
Palmer JE and Benson CE | Effect of treatment with erythromycin and rifampin during the acute stages of experimentally induced equine ehrlichial colitis in ponies. | 1992 | Am. J. Vet. Res. | pmid:1466503 |
Ramstedt KL et al. | Changes in gallbladder volume in healthy dogs after food was withheld for 12 hours followed by ingestion of a meal or a meal containing erythromycin. | 2008 | Am. J. Vet. Res. | pmid:18447796 |
Lakritz J et al. | Comparison of microbiologic and high-performance liquid chromatography assays to determine plasma concentrations, pharmacokinetics, and bioavailability of erythromycin base in plasma of foals after intravenous or intragastric administration. | 1999 | Am. J. Vet. Res. | pmid:10211682 |
Koenig JB et al. | Binding of radiolabeled porcine motilin and erythromycin lactobionate to smooth muscle membranes in various segments of the equine gastrointestinal tract. | 2002 | Am. J. Vet. Res. | pmid:12428665 |
DeGeeter MJ and Stahl GL | Sensitivity of Escherichia coli after exposure to lincomycin in vitro and in vivo. | 1976 | Am. J. Vet. Res. | pmid:776050 |
Smith JA et al. | Inhibitory and lethal activities of rosaramicin, erythromycin, and clindamycin against Campylobacter fetus subsp jejuni and intestinalis. | 1983 | Am. J. Vet. Res. | pmid:6625312 |