erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Oyarzún E et al. | Antibiotic treatment in preterm labor and intact membranes: a randomized, double-blinded, placebo-controlled trial. | 1998 May-Jun | J Matern Fetal Med | pmid:9642605 |
Shimatani T | Involvement of cholinergic motor neurons in pharmacological regulation of gastrointestinal motility by glucagon in conscious dogs. | 1997 Aug-Oct | J Smooth Muscle Res | pmid:9639019 |
Havlik J and Holý M | [Erythromycin stearate Spofa--coated tablets for pediatric practice]. | 1976 | Cesk Pediatr | pmid:963828 |
Novaes AB et al. | Immediate implants placed into infected sites: a histomorphometric study in dogs. | 1998 May-Jun | Int J Oral Maxillofac Implants | pmid:9638015 |
Stassi DL et al. | Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9636144 |
Wandel C et al. | Effect of CYP3A inhibition on vesnarinone metabolism in humans. | 1998 | Clin. Pharmacol. Ther. | pmid:9630823 |
Wirsing von König CH et al. | Factors influencing the spread of pertussis in households. | 1998 | Eur. J. Pediatr. | pmid:9625336 |
Souli M et al. | In vitro activity of BAY 12-8039, a new fluoroquinolone, against species representative of respiratory tract pathogens. | 1998 | Int. J. Antimicrob. Agents | pmid:9624540 |
Roblin PM and Hammerschlag MR | In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9624507 |
Reinert RR et al. | In vitro activities of the new ketolide antibiotics HMR 3004 and HMR 3647 against Streptococcus pneumoniae in Germany. | 1998 | Antimicrob. Agents Chemother. | pmid:9624505 |