erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kataja J et al. | Different erythromycin resistance mechanisms in group C and group G streptococci. | 1998 | Antimicrob. Agents Chemother. | pmid:9624500 |
Muli F and Struthers JK | Use of a continuous-culture biofilm system to study the antimicrobial susceptibilities of Gardnerella vaginalis and Lactobacillus acidophilus. | 1998 | Antimicrob. Agents Chemother. | pmid:9624489 |
Rosato A et al. | A new ketolide, HMR 3004, active against streptococci inducibly resistant to erythromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9624482 |
Widdowson CA and Klugman KP | Emergence of the M phenotype of erythromycin-resistant pneumococci in South Africa. | 1998 Apr-Jun | Emerging Infect. Dis. | pmid:9621199 |
Kruppa A et al. | Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin. | 1998 | Dermatology (Basel) | pmid:9621142 |
Kudoh S et al. | Improvement of survival in patients with diffuse panbronchiolitis treated with low-dose erythromycin. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9620913 |
Krone LV | The importance of multiple antibiotic coverage for hospitalized patients when the community acquired pneumonia is Legionnaire's disease. | 1998 | WMJ | pmid:9617308 |
Syphilis--recommended treatment schedules, 1976. | 1976 | Am Fam Physician | pmid:961559 | |
Bourrat E et al. | [Rosacea with ocular involvement in a child]. | 1996 | Ann Dermatol Venereol | pmid:9615130 |
Mathis C and Malbert CH | Changes in pyloric resistance induced by erythromycin. | 1998 | Neurogastroenterol. Motil. | pmid:9614671 |