erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nastasyak IN | [Localization of rifampicin resistance determinants on genetic map of Saccharopolyspora erythraea]. | 1997 | Antibiot. Khimioter. | pmid:9412406 |
Nakashio S et al. | [Comparative antimicrobial activity of RP 59,500 (quinupristin-dalfopristin), the first semisynthetic injectable streptgramin, against gram-positive cocci and other recent clinical pathogens]. | 1997 | Jpn J Antibiot | pmid:9412874 |
Kitazawa T et al. | Functional characterization of neural and smooth muscle motilin receptors in the chicken proventriculus and ileum. | 1997 | Regul. Pept. | pmid:9416990 |
Luft FC | Antimicrobials in kidney and liver failure. | 1976 | Am Fam Physician | pmid:941822 |
Sakran W et al. | [Isolated susceptibility of Streptococcus pyogenes to 3 macrolides]. | 1997 | Harefuah | pmid:9418339 |
Taylor DE et al. | Cloning and sequence analysis of two copies of a 23S rRNA gene from Helicobacter pylori and association of clarithromycin resistance with 23S rRNA mutations. | 1997 | Antimicrob. Agents Chemother. | pmid:9420030 |
Clancy J et al. | Cloning and characterization of a novel macrolide efflux gene, mreA, from Streptococcus agalactiae. | 1997 | Antimicrob. Agents Chemother. | pmid:9420045 |
Occhialini A et al. | Macrolide resistance in Helicobacter pylori: rapid detection of point mutations and assays of macrolide binding to ribosomes. | 1997 | Antimicrob. Agents Chemother. | pmid:9420046 |
Caron F et al. | Influence of erythromycin resistance, inoculum growth phase, and incubation time on assessment of the bactericidal activity of RP 59500 (quinupristin-dalfopristin) against vancomycin-resistant Enterococcus faecium. | 1997 | Antimicrob. Agents Chemother. | pmid:9420051 |
Smith RP et al. | Effect of levofloxacin, erythromycin or rifampicin pretreatment on growth of Legionella pneumophila in human monocytes. | 1997 | J. Antimicrob. Chemother. | pmid:9421315 |
Fischman AJ et al. | The role of positron emission tomography in pharmacokinetic analysis. | 1997 | Drug Metab. Rev. | pmid:9421680 |
Guin JD et al. | Antibiotic sensitivity of comedonal Propionibacterium acnes. | 1979 | Acta Derm. Venereol. | pmid:94223 |
Ruzin A and Novick RP | Glycerol monolaurate inhibits induction of vancomycin resistance in Enterococcus faecalis. | 1998 | J. Bacteriol. | pmid:9422612 |
Marsden AF et al. | Engineering broader specificity into an antibiotic-producing polyketide synthase. | 1998 | Science | pmid:9422686 |
Midolo PD et al. | Antimicrobial resistance testing of Helicobacter pylori: a comparison of Etest and disk diffusion methods. | 1997 | Pathology | pmid:9423225 |
Martins JC et al. | Optimal detection of weak nJ(1H- 119Sn) couplings by gradient-enhanced 1D and 2D heteronuclear multiple-quantum correlation spectroscopy. Application to a novel tin derivative of erythromycin A. | 1997 | J. Magn. Reson. | pmid:9424309 |
Passerini de Rossi BN et al. | [Selection of Bvg- variants of Bordetella pertussis]. | 1997 Apr-Jun | Rev. Argent. Microbiol. | pmid:9424628 |
Rooney G and Robinson A | Look out for the hidden STD. | 1997 | Practitioner | pmid:9425710 |
Ross EA and Koo LC | Improved nutrition after the detection and treatment of occult gastroparesis in nondiabetic dialysis patients. | 1998 | Am. J. Kidney Dis. | pmid:9428453 |
Park HJ et al. | Effect of erythromycin on gastric emptying in healthy individuals assessed by radio-opaque markers and plasma acetaminophen levels. | 1997 | J. Gastroenterol. | pmid:9430010 |
Freidank H | [Diagnosis and therapy of Chlamydia pneumoniae and trachomatis]. | 1997 | Internist (Berl) | pmid:9432510 |
Folwaczny C et al. | [Effects of various prokinetic drugs on gastrointestinal transit times in patients with progressive systemic scleroderma]. | 1997 | Z Gastroenterol | pmid:9432812 |
Karbowski M et al. | Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes. | 1997 | Biochim. Biophys. Acta | pmid:9434138 |
Fenton LJ and Light IJ | Congenital syphilis after maternal treatment with erythromycin. | 1976 | Obstet Gynecol | pmid:943741 |
Chen B et al. | Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release. | 1997 | Respirology | pmid:9441129 |
Cocuzza CE et al. | High incidence of erythromycin-resistant Streptococcus pyogenes in Monza (North Italy) in untreated children with symptoms of acute pharyngo-tonsillitis: an epidemiological and molecular study. | 1997 | Microb. Drug Resist. | pmid:9442490 |
Granados MA and French L | Antibiotic treatment in preterm PROM. | 1998 | J Fam Pract | pmid:9451358 |
Shirai R et al. | [Analysis of cases allowed to cease erythromycin therapy for diffuse panbronchiolitis--comparative study between patients with cessation of the therapy and patients continuing the therapy]. | 1997 | Kansenshogaku Zasshi | pmid:9455056 |
Yeates RA et al. | Pharmacokinetic and pharmacodynamic interaction study between midazolam and the macrolide antibiotics, erythromycin, clarithromycin, and the azalide azithromycin. | 1997 | Int J Clin Pharmacol Ther | pmid:9455717 |
Mathis C and Malbert CH | Erythromycin gastrokinetic activity is partially vagally mediated. | 1998 | Am. J. Physiol. | pmid:9458776 |
Borek AP et al. | Evolving clinical problems with Streptococcus pneumoniae: increasing resistance to antimicrobial agents, and failure of traditional optochin identification in Chicago, Illinois, between 1993 and 1996. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9458976 |
Pfaller MA et al. | Nosocomial streptococcal blood stream infections in the SCOPE Program: species occurrence and antimicrobial resistance. The SCOPE Hospital Study Group. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9458983 |
Pfaller MA et al. | In vitro activity of cefepime and ceftazidime against 197 nosocomial blood stream isolates of streptococci: a multicenter sample. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9458985 |
Rampling A et al. | Community-acquired Legionnaires' disease following minimal exposure to a contaminated source. | 1997 | J. Infect. | pmid:9459407 |
Nalepa P and Micherdzińska K | [Severe pneumonia caused by Chlamydia pneumoniae in a patient treated with steroids for bronchial asthma]. | 1997 | Pol. Merkur. Lekarski | pmid:9461730 |
Angeles BL et al. | A bacterial sensitivity test to determine the effectiveness of minocycline HCI (Minocin), erythromycin (Erythrocin) and ampicillin (Ampicin) on the predominant microorganisms present in a diseased periodontium. | 1994 Jun-Aug | J Philipp Dent Assoc | pmid:9462063 |
Zurabyan VA et al. | [In vitro influence of biologically active factors of microorganisms on antibiotic susceptibility of Yersinia pestis]. | 1997 | Antibiot. Khimioter. | pmid:9463297 |
Sadovnikova SF and Selina EV | [Five years of sumamed on Russian market]. | 1997 | Antibiot. Khimioter. | pmid:9463300 |
Granovsky-Grisaru S et al. | Effects of erythromycin on contractility of isolated myometrium from pregnant rats. | 1998 | Am. J. Obstet. Gynecol. | pmid:9465824 |
Tsuruta S et al. | Inhibition of nifedipine metabolism in dogs by erythromycin: difference between the gut wall and the liver. | 1997 | J. Pharm. Pharmacol. | pmid:9466344 |
Dobson RL | Diagnosis and treatment of eczema. | 1976 | JAMA | pmid:946853 |
Adair CD et al. | Chlamydia in pregnancy: a randomized trial of azithromycin and erythromycin. | 1998 | Obstet Gynecol | pmid:9469269 |
Gurevitz SL | Erythromycin: drug interactions. | 1997 | J Dent Hyg | pmid:9470569 |
Alegre M et al. | [Psychosis due to the interaction of erythromycin and bromocriptine in Parkinson disease]. | 1997 | Neurologia | pmid:9471184 |
Mast WE and Burrows WM | Erythema chronicum migrans in the United States. | 1976 | JAMA | pmid:947268 |
Schuetz EG et al. | Human MDR1 and mouse mdr1a P-glycoprotein alter the cellular retention and disposition of erythromycin, but not of retinoic acid or benzo(a)pyrene. | 1998 | Arch. Biochem. Biophys. | pmid:9473310 |
Fazekas T et al. | Suppression of erythromycin-induced early afterdepolarizations and torsade de pointes ventricular tachycardia by mexiletine. | 1998 | Pacing Clin Electrophysiol | pmid:9474662 |
Volmer DA and Hui JP | Study of erythromycin A decomposition products in aqueous solution by solid-phase microextraction/liquid chromatography/tandem mass spectrometry. | 1998 | Rapid Commun. Mass Spectrom. | pmid:9474800 |
Vining LC | Antibiotic tolerance in producer organisms. | 1979 | Adv. Appl. Microbiol. | pmid:94753 |
Gubina M et al. | Septicaemia and meningitis with campylobacter fetus subspecies intestinalis. | 1976 | Infection | pmid:947847 |