erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Zhang FC | [Radiologic manifestations of Legionnaires' disease (report of 2 cases)]. | 1985 | Zhonghua Fang She Xue Za Zhi | pmid:2938897 |
Ding YF et al. | [Relation of pbp2B, ermB, ermA/B, mefA genes with resistance to penicillin and erythromycin among Streptococcus pneumoniae isolates from children]. | 2005 | Zhonghua Er Ke Za Zhi | pmid:15924755 |
Hua CZ et al. | [Antibiotics-resistance pattern and genetic type of Streptococcus pneumoniae isolated from children in Hangzhou]. | 2004 | Zhonghua Er Ke Za Zhi | pmid:14990098 |
Ge LL et al. | [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. | 2017 | Zhonghua Er Ke Za Zhi | pmid:28173648 |
Su WD et al. | [Chymothorax in a newborn infant]. | 2003 | Zhonghua Er Ke Za Zhi | pmid:14723819 |
He S et al. | [Clinical analysis of scrub typhus-associated hemophagocytic syndrome]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25476431 |
Sun ZY et al. | [Epidemiological study of Streptococcus pneumoniae in the nasopharynx of healthy children under 5 years of age in Wuhan]. | 2007 | Zhonghua Er Ke Za Zhi | pmid:17697628 |
Hua CZ et al. | [An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015: a multi-center retrospective study]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:27510868 |
Wang CH et al. | [Effect of interstitial cells of Cajal on gastrointestinal motility induced by motilin receptor agonist ABT-229]. | 2010 | Zhonghua Er Ke Za Zhi | pmid:20654011 |
Liu H et al. | [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:26875461 |
He JX et al. | [Demonstration of a mechanism of anti-inflammatory effect of erythromycin on allergic airway inflammation in rat]. | 2005 | Zhonghua Er Ke Za Zhi | pmid:15833193 |
Yang H et al. | [Macrolide-resistant Streptococcus pneumoniae in the pediatric population in Beijing]. | 2004 | Zhonghua Er Ke Za Zhi | pmid:15733368 |
Hua CZ et al. | [Drug-resistance of staphylococcus aureus and detection of mecA gene in all strains isolated from children in Hangzhou]. | 2006 | Zhonghua Er Ke Za Zhi | pmid:16780714 |
Xu SN et al. | [Effect of erythromycin on apoptosis of epithelial cell in nasal polyps]. | 2006 | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:17007374 |
Tang J and Li Y | [Effect of erythromycin on the expression of apoptotic gene on eosinophils in nasal polyps in vitro]. | 2003 | Zhonghua Er Bi Yan Hou Ke Za Zhi | pmid:15040110 |
Tang J et al. | [Effect of erythromycin on apoptosis of eosinophils in nasal polyps in vitro]. | 2002 | Zhonghua Er Bi Yan Hou Ke Za Zhi | pmid:12768725 |
Guan Y et al. | [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23724685 |
Guan Y et al. | [Preliminary study of effects of andrographolide on Staphylococcus epidermidis biofilms]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23126203 |
Jia P et al. | [Regulative effect of electroacupuncture of different frequencies on derangement of gastric electric rhythm in rabbits]. | 2006 | Zhongguo Zhen Jiu | pmid:17165505 |
Sun XR et al. | [Effect of motilin receptor agonist-erythromycin on the glucose responsive neurons in hypothalamus of rats]. | 2005 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21162186 |