erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Ishikawa Y et al. | Inactivation kinetics and residual activity of CYP3A4 after treatment with erythromycin. | 2017 | Biopharm Drug Dispos | pmid:28425104 |
Rea E and Husbands E | Erythromycin: prophylaxis against recurrent small bowel obstruction. | 2017 | BMJ Support Palliat Care | pmid:28356304 |
Hawkins PA et al. | Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA. | 2017 | J. Antimicrob. Chemother. | pmid:28333320 |
Štšepetova J et al. | Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. | 2017 | J. Appl. Microbiol. | pmid:28574626 |
Tanaka Y et al. | Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28532245 |
Demczuk WHB et al. | Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. | 2017 | PLoS ONE | pmid:28531208 |
Cheled-Shoval S et al. | From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. | 2017 | Molecules | pmid:28513558 |
Sato T et al. | Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. | 2017 | Microbiol. Immunol. | pmid:28504455 |
Wozniak A et al. | Importance of adhesins in the recurrence of pharyngeal infections caused by Streptococcus pyogenes. | 2017 | J. Med. Microbiol. | pmid:28463664 |
Pavlova A et al. | Toward the rational design of macrolide antibiotics to combat resistance. | 2017 | Chem Biol Drug Des | pmid:28419786 |
Szczepanska B et al. | Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. | 2017 | BMC Microbiol. | pmid:28376713 |
Selwood DL | Macrocycles, the edge of drug-likeness chemical space or Goldilocks zone? | 2017 | Chem Biol Drug Des | pmid:28205398 |
Pergola S et al. | Genetic diversity and antimicrobial resistance profiles of Campylobacter coli and Campylobacter jejuni isolated from broiler chicken in farms and at time of slaughter in central Italy. | 2017 | J. Appl. Microbiol. | pmid:28194914 |
Huang YW et al. | Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia. | 2017 | Antimicrob. Agents Chemother. | pmid:28193669 |
Ge LL et al. | [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. | 2017 | Zhonghua Er Ke Za Zhi | pmid:28173648 |
Giguère S | Treatment of Infections Caused by Rhodococcus equi. | 2017 | Vet. Clin. North Am. Equine Pract. | pmid:28161038 |
Wang Y et al. | Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28129976 |
Owen L et al. | A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. | 2017 | Phytother Res | pmid:28124400 |
Chen K et al. | Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China. | 2017 | BMC Infect. Dis. | pmid:28122513 |
Kassem II et al. | Antimicrobial-Resistant Campylobacter in Organically and Conventionally Raised Layer Chickens. | 2017 | Foodborne Pathog. Dis. | pmid:27768387 |
Song KH et al. | Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort. | 2017 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:27714592 |
Austin BA and Fleischer AB | The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin. | 2017 | J Dermatolog Treat | pmid:27425633 |
Jakubů V et al. | Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. | 2017 | Cent. Eur. J. Public Health | pmid:29346850 |
Olajuyigbe OO et al. | In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. | 2017 | Acta Biochim. Pol. | pmid:28612062 |
Weber JM et al. | Application of In Vitro Transposon Mutagenesis to Erythromycin Strain Improvement in Saccharopolyspora erythraea. | 2017 | Methods Mol. Biol. | pmid:27709581 |
Duelge KJ et al. | An LC-MS/MS method for the determination of antibiotic residues in distillers grains. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28415016 |
Li LH et al. | [Effect of low dose erythromycin on the proliferation of granulation tissue after tracheal injury]. | 2017 | Zhonghua Yi Xue Za Zhi | pmid:28316160 |
Fohner AE et al. | PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. | 2017 | Pharmacogenet. Genomics | pmid:28146011 |
Michael-Kordatou I et al. | On the capacity of ozonation to remove antimicrobial compounds, resistant bacteria and toxicity from urban wastewater effluents. | 2017 | J. Hazard. Mater. | pmid:26947803 |
Kumpfmüller J et al. | Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26432460 |
Deloose E et al. | Higher plasma motilin levels in obese patients decrease after Roux-en-Y gastric bypass surgery and regulate hunger. | 2016 | Gut | pmid:25986945 |
Hadjipanayis A et al. | Nasopharyngeal Pneumococcal Carriage among Healthy Children in Cyprus Post Widespread Simultaneous Implementation of PCV10 and PCV13 Vaccines. | 2016 | PLoS ONE | pmid:27706247 |
Krishnamoorthy G et al. | Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane. | 2016 | Antimicrob. Agents Chemother. | pmid:27697764 |
Li M et al. | Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China. | 2016 | Int J Mol Sci | pmid:27669217 |
Ababou A and Koronakis V | Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. | 2016 | PLoS ONE | pmid:27403665 |
Yuan QB et al. | Reductions of bacterial antibiotic resistance through five biological treatment processes treated municipal wastewater. | 2016 | Environ Sci Pollut Res Int | pmid:27384166 |
Karlsson E et al. | Clonality of erythromycin resistance in Francisella tularensis. | 2016 | J. Antimicrob. Chemother. | pmid:27334667 |
Changchien CH et al. | Antibiotic susceptibility and genomic variations in Staphylococcus aureus associated with Skin and Soft Tissue Infection (SSTI) disease groups. | 2016 | BMC Infect. Dis. | pmid:27287530 |
Waiser MJ et al. | Effects of erythromycin, trimethoprim and clindamycin on attached microbial communities from an effluent dominated prairie stream. | 2016 | Ecotoxicol. Environ. Saf. | pmid:27261880 |
KarniÄar K et al. | Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea. | 2016 | Microb. Cell Fact. | pmid:27255285 |
Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
Diawara I et al. | Phenotypic and genotypic characterization of Streptococcus pneumoniae resistant to macrolide in Casablanca, Morocco. | 2016 | Infect. Genet. Evol. | pmid:26961592 |
Sierra-Arguello YM et al. | Fluoroquinolone and macrolide resistance in Campylobacter jejuni isolated from broiler slaughterhouses in southern Brazil. | 2016 | Avian Pathol. | pmid:26925976 |
Molina-Manso D et al. | Effect of different agents with potential antibiofilm activity on antimicrobial susceptibility of biofilms formed by Staphylococcus spp. isolated from implant-related infections. | 2016 | J. Antibiot. | pmid:26905757 |
Madmanang S et al. | Constituents of Fagraea fragrans with Antimycobacterial Activity in Combination with Erythromycin. | 2016 | J. Nat. Prod. | pmid:26905094 |
Jin Y et al. | From the Cover: Exposure to Oral Antibiotics Induces Gut Microbiota Dysbiosis Associated with Lipid Metabolism Dysfunction and Low-Grade Inflammation in Mice. | 2016 | Toxicol. Sci. | pmid:27503388 |
Parhizgari N et al. | High frequency of multidrug-resistant Staphylococcus aureus with SCCmec type III and Spa types t037 and t631 isolated from burn patients in southwest of Iran. | 2016 | APMIS | pmid:26709106 |
Chuang MC et al. | Diffuse panbronchiolitis-The response and recurrence after erythromycin therapy. | 2016 | J. Formos. Med. Assoc. | pmid:26705139 |
Broad J et al. | RQ-00201894: A motilin receptor agonist causing long-lasting facilitation of human gastric cholinergically-mediated contractions. | 2016 | J. Pharmacol. Sci. | pmid:26685754 |
Shimizu T and Suzaki H | Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. | 2016 | Auris Nasus Larynx | pmid:26441370 |