erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Rodriguez WJ et al. | Erythromycin-sulfisoxazole vs amoxicillin in the treatment of acute otitis media in children. A double-blind, multiple-dose comparative study. | 1985 | Am. J. Dis. Child. | pmid:3895889 |
Howie VM and Ploussard JH | Compliance dose-response relationships in streptococcal pharyngitis. | 1972 | Am. J. Dis. Child. | pmid:4622022 |
BURNS L and HODGMAN J | STUDIES OF PREMATURES GIVEN ERYTHROMYCIN ESTOLATE. | 1963 | Am. J. Dis. Child. | pmid:14057607 |
Maruyama S et al. | Sensitivity of group A streptococci to antibiotics. Prevalence of resistance to erythromycin in Japan. | 1979 | Am. J. Dis. Child. | pmid:389035 |
Derrick CW and Dillon HC | Streptococcal pharyngitis therapy. A comparison of two erythromycin formulations. | 1979 | Am. J. Dis. Child. | pmid:389036 |
Pai CH et al. | Erythromycin in treatment of Campylobacter enteritis in children. | 1983 | Am. J. Dis. Child. | pmid:6600579 |
Disney FA and Pichichero ME | Treatment of Staphylococcus aureus infections in children in office practice. | 1983 | Am. J. Dis. Child. | pmid:6600877 |
Aiello LF and Luby JP | Concomitant Mycoplasma and adenovirus infection in a family. | 1974 | Am. J. Dis. Child. | pmid:4374082 |
Lloyd-Still JD et al. | Erythromycin estolate hepatotoxicity. | 1978 | Am. J. Dis. Child. | pmid:629252 |
Wannamaker LW | Perplexity and precision in the diagnosis of streptococcal pharyngitis. | 1972 | Am. J. Dis. Child. | pmid:5056872 |
HUXTABLE KA et al. | STAPHYLOCOCCAL PNEUMONIA IN CHILDHOOD; LONG-TERM FOLLOW-UP. | 1964 | Am. J. Dis. Child. | pmid:14168063 |
Feigin RD et al. | Osteomyelitis of the calcaneus. Report of eight cases. | 1970 | Am. J. Dis. Child. | pmid:5410295 |
Esterly NB et al. | Impetigo. | 1991 | Am. J. Dis. Child. | pmid:1899777 |
Hughes WT and Collier RN | Streptococcal pharyngitis. Evaluation of erythromycin, erythromycin-sulfas, and sulfamethoxazole (possible antagonism between erythromycin and sulfas). | 1969 | Am. J. Dis. Child. | pmid:5348368 |
Sprauer MA et al. | Prevention of secondary transmission of pertussis in households with early use of erythromycin. | 1992 | Am. J. Dis. Child. | pmid:1733147 |
Dillon HC and Ware JC | Sources and susceptibilities of staphylococci isolated from children. A seven-year survey. | 1981 | Am. J. Dis. Child. | pmid:7234768 |
Breese BB et al. | Streptococcal infections in children. Comparison of the therapeutic effectiveness of erythromycin administered twice daily with erythromycin, penicillin phenoxymethyl, and clindamycin administered three times daily. | 1974 | Am. J. Dis. Child. | pmid:4213398 |
Robins-Browne RM et al. | Treatment of Campylobacter-associated enteritis with erythromycin. | 1983 | Am. J. Dis. Child. | pmid:6337473 |
Drusin LM et al. | Group C streptococcal colonization in a newborn nursery. | 1973 | Am. J. Dis. Child. | pmid:4708274 |
Phair JP et al. | Penicillin phenoxymethyl. Use in rheumatic fever prophylaxis. | 1973 | Am. J. Dis. Child. | pmid:4198746 |
Harrison HS et al. | Congenital laryngeal cleft: report of a case. A comparison with other types of tracheo-esophageal communication. | 1965 | Am. J. Dis. Child. | pmid:5846694 |
Garber MJ | Erythromycin-resistant group A streptococci. | 1981 | Am. J. Dis. Child. | pmid:7015829 |
Khuri-Bulos N et al. | Bacteroides brain abscess treated with clindamycin. | 1973 | Am. J. Dis. Child. | pmid:4723176 |
Stallings MW and Archer SB | Atypical Mycoplasma pneumonia. | 1973 | Am. J. Dis. Child. | pmid:4759371 |
Davis SD et al. | Partial antibiotic therapy in Haemophilus infuenzae meningitis. Its effect on cerebrospinal fluid abnormalities. | 1975 | Am. J. Dis. Child. | pmid:1080009 |
Hughes WT and Wan RT | Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. | 1967 | Am. J. Dis. Child. | pmid:4290285 |
Breese BB et al. | B-hemolytic streptococcal illness. A comparison of the effectiveness of penicillin G, triacetyloleandomycin, and erythromycin estolate. | 1966 | Am. J. Dis. Child. | pmid:5322797 |
Wittler RR et al. | Penicillin tolerance and erythromycin resistance of group A beta-hemolytic streptococci in Hawaii and the Philippines. | 1990 | Am. J. Dis. Child. | pmid:2184661 |
Lascari AD et al. | Varicella-like rash associated with Mycoplasma infection. | 1974 | Am. J. Dis. Child. | pmid:4855375 |
Klugman KP et al. | Clinical and nasopharyngeal isolates of unusual multiply resistant pneumococci. | 1986 | Am. J. Dis. Child. | pmid:3766492 |
Halsey NA et al. | Nosocomial pertussis: a failure of erythromycin treatment and prophylaxis. | 1980 | Am. J. Dis. Child. | pmid:7377164 |
HALTALIN KC and NELSON JD | HAND-FOOT SYNDROME DUE TO STREPTOCOCCAL INFECTION. | 1965 | Am. J. Dis. Child. | pmid:14237416 |
Bruhn FW | Lyme disease. | 1984 | Am. J. Dis. Child. | pmid:6711502 |
Bass JW et al. | Susceptibility of Bordetella pertussis to nine antimicrobial agents. | 1969 | Am. J. Dis. Child. | pmid:4303822 |
Slotkin RI et al. | The effect of antibiotics on Mycoplasma pneumoniae in vitro and in vivo. | 1967 | Am. J. Epidemiol. | pmid:5006447 |
Carbonell N et al. | Erythromycin infusion prior to endoscopy for acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial. | 2006 | Am. J. Gastroenterol. | pmid:16771939 |
Janssen P et al. | The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. | 2013 | Am. J. Gastroenterol. | pmid:24005344 |
VIRANUVATTI V and BISESHURARIT P | Clinical trial of erythromycin in amebic liver abscess. | 1955 | Am. J. Gastroenterol. | pmid:13228406 |
Jones KL et al. | The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. | 1999 | Am. J. Gastroenterol. | pmid:10445530 |
Fiorucci S et al. | Effect of erythromycin on gastric and gallbladder emptying and gastrointestinal symptoms in scleroderma patients is maintained medium term. | 1994 | Am. J. Gastroenterol. | pmid:8147358 |
Camilleri M | The current role of erythromycin in the clinical management of gastric emptying disorders. | 1993 | Am. J. Gastroenterol. | pmid:8424415 |
Keshavarzian A and Isaac RM | Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. | 1993 | Am. J. Gastroenterol. | pmid:8424419 |
Ruffin WK | Erythromycin: a postoperative jumpstart? | 1994 | Am. J. Gastroenterol. | pmid:7909647 |
CURTIN JA | THE EFFECT OF ANTIBIOTICS UPON THE GASTROINTESTINAL TRACT. | 1964 | Am. J. Gastroenterol. | pmid:14206198 |
Koutsoumbi P et al. | The effect of erythromycin on human esophageal motility is mediated by serotonin receptors. | 2000 | Am. J. Gastroenterol. | pmid:11151866 |
Portincasa P et al. | The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study. | 2000 | Am. J. Gastroenterol. | pmid:11151875 |
Ecker JA et al. | Pseudomembraneous enterocolitis--an unwelcome gastrointestinal complication of antibiotic therapy. | 1970 | Am. J. Gastroenterol. | pmid:4319211 |
Moussa F et al. | Erythromycin eye ointment: effect on gastrointestinal motility. | 2000 | Am. J. Gastroenterol. | pmid:10710093 |
Kalkay MN et al. | Campylobacter-induced toxic megacolon. | 1983 | Am. J. Gastroenterol. | pmid:6613968 |
Masclee AA et al. | Effect of erythromycin on gallbladder emptying in patients with antrectomy or truncal vagotomy. | 1995 | Am. J. Gastroenterol. | pmid:7771433 |