erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Ileus D045823 3 associated lipids
Sporotrichosis D013174 3 associated lipids
Pleural Effusion D010996 3 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Radiodermatitis D011855 3 associated lipids
Intestinal Atresia D007409 3 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Dry Socket D004368 3 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Empyema D004653 3 associated lipids
Erythema Multiforme D004892 3 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Surgical Wound Dehiscence D013529 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Pneumonia, Pneumococcal D011018 3 associated lipids
Orthomyxoviridae Infections D009976 3 associated lipids
Superinfection D015163 3 associated lipids
Scleritis D015423 3 associated lipids
Uterine Cervical Incompetence D002581 3 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Toothache D014098 3 associated lipids
Meningitis, Haemophilus D008583 3 associated lipids
Psittacosis D009956 4 associated lipids
Mycetoma D008271 4 associated lipids
Periapical Diseases D010483 4 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Pleural Diseases D010995 4 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Chancroid D002602 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Balanitis D001446 4 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Yaws D015001 4 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Foot Diseases D005534 4 associated lipids
Parotitis D010309 4 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Red-Cell Aplasia, Pure D012010 4 associated lipids
Splenomegaly D013163 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Blepharitis D001762 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Schuster-Bruce M Gastric emptying in the critically ill. 2001 Crit. Care Med. pmid:11395631
Svejda J and Richter J [The hepatotoxic action of erythromycin (author's transl)]. 1975 Cas. Lek. Cesk. pmid:1139592
Rospide MF et al. Comparative antimicrobial activity of ABT-773, a novel ketolide, tested against drug-resistant Gram-positive cocci and Haemophilus influenzae. 2001 Int. J. Antimicrob. Agents pmid:11397614
Lim J and Yun H Postantibiotic effects and postantibiotic sub-MIC effects of erythromycin, roxithromycin, tilmicosin, and tylosin on Pasteurella multocida. 2001 Int. J. Antimicrob. Agents pmid:11397617
Usary J and Champney WS Erythromycin inhibition of 50S ribosomal subunit formation in Escherichia coli cells. 2001 Mol. Microbiol. pmid:11401702
Butrous G and Siegel RL Sildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. 2001 Circulation pmid:11401951
Píriz S et al. Comparison of erythromycin and oxytetracycline for the treatment of ovine footrot. 2001 Acta Vet. Hung. pmid:11402641
Takahashi T et al. Erythromycin attenuates an experimental model of chronic bronchiolitis via augmenting monocyte chemoattractant protein-1. 2001 Eur. Respir. J. pmid:11405512
Ng E and Shah V Erythromycin for feeding intolerance in preterm infants. 2001 Cochrane Database Syst Rev pmid:11406010
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Hoban DJ et al. Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: prevalence of mef(A) and erm(B) and susceptibilities to ketolides. 2001 Antimicrob. Agents Chemother. pmid:11408241
Nilius AM et al. Comparative in vitro activity of ABT-773, a novel antibacterial ketolide. 2001 Antimicrob. Agents Chemother. pmid:11408246
Miller SD Madura foot: treatment of Nocardia nova infection with antibiotics alone. 2001 Am J. Orthop. pmid:11411876
Yin Y et al. Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase. 2001 Bioorg. Med. Chem. Lett. pmid:11412964
Chrysos E et al. Erythromycin enhances oesophageal motility in patients with gastro-oesophageal reflux. 2001 ANZ J Surg pmid:11413601
Losa M et al. CI (critical incidents) vs. CI (corporate identity). 2001 Swiss Med Wkly pmid:11416892
Grub S et al. The interaction of saquinavir (soft gelatin capsule) with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients. 2001 Eur. J. Clin. Pharmacol. pmid:11417442
Gregory ST et al. Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21. 2001 J. Bacteriol. pmid:11418580
Canzano JC and Lim JI Pars plana vitrectomy for epiretinal membrane secondary to cat scratch neuroretinitis. 2001 Retina (Philadelphia, Pa.) pmid:11421023
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Gutschow CA et al. Bile exposure of the denervated stomach as an esophageal substitute. 2001 Ann. Thorac. Surg. pmid:11426748
McGee L et al. Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. 2001 J. Clin. Microbiol. pmid:11427569
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Honba K et al. [Erythromycin uptake pathways in Shigella]. 2001 Jpn J Antibiot pmid:11436833
Komiya N and Tamaoki K [Therapeutic effects of macrolides on patients with psoriasis vulgaris, pigmentary prurigo, or eosinophilic pustule folliculitis]. 2001 Jpn J Antibiot pmid:11439883
Matsunaga Y et al. [Therapeutic effects of macrolides on patients with palmoplantar pustulosis]. 2001 Jpn J Antibiot pmid:11439885
Azuma A et al. [Case of the bare lymphocyte syndrome successfully treated with long-term small dosage administration of erythromycin]. 2001 Jpn J Antibiot pmid:11439887
Takahashi T et al. [Effects of erythromycin on the Pseudomonas-induced rabbit diffuse panbronchiolitis model--the improvements in granuloma-like lesions with increasing production of MCP-1]. 2001 Jpn J Antibiot pmid:11439890
Enomoto F et al. [Effects of macrolides on cultured rat vascular cells]. 2001 Jpn J Antibiot pmid:11439891
Hashimoto N et al. [Effects of erythromycin on matrix metalloproteinase-9(MMP-9)and cell migration]. 2001 Jpn J Antibiot pmid:11439893
Inesawa H et al. [Effects of macrolide antibiotics on immune cells derived from human peripheral blood]. 2001 Jpn J Antibiot pmid:11439894
Dobashi Y et al. [Effects of macrolides on neutrophil apoptosis, IL-8 production, and neutrophil clearance mechanism]. 2001 Jpn J Antibiot pmid:11439897
Taguchi Y [Guidelines for small dosage macrolide therapy of patients with diffuse panbronchiolitis and reports of adverse effects]. 2001 Jpn J Antibiot pmid:11439900
Tamaoki A et al. [Effects and action mechanisms of macrolides on IgG- immune complex lung injury models]. 2001 Jpn J Antibiot pmid:11439907
Idesaki M et al. [Effects of various erythromycin derivatives on activation of transcription factors in airway epithelial cells]. 2001 Jpn J Antibiot pmid:11439910
Brandt CM et al. Macrolide resistance in Streptococcus pyogenes isolates from throat infections in the region of Aachen, Germany. 2001 Microb. Drug Resist. pmid:11442342
Corneau N et al. A coelectroporation method for the isolation of cryptic plasmids from Lactococcus lactis. 2001 Lett. Appl. Microbiol. pmid:11442806
Garzotti M et al. Coupling of a supercritical fluid chromatography system to a hybrid (Q-TOF 2) mass spectrometer: on-line accurate mass measurements. 2001 Rapid Commun. Mass Spectrom. pmid:11445901
Dubois J and St -Pierre C In vitro activity of ABT-773 versus macrolides and quinolones against resistant respiratory tract pathogens. 2001 May-Jun Diagn. Microbiol. Infect. Dis. pmid:11448561
Lo Bue AM et al. Antibacterial activity and post-antibiotic effect of flurithromycin compared with other macrolides and penicillins against periodontal pathogens. 2001 J Chemother pmid:11450882
Gregory D et al. Activity of penicillin, erythromycin, and cephalosporins against isolates of Corynebacterium diphtheriae from cutaneous lesions. 1979 J. Antimicrob. Chemother. pmid:114513
Clarebout G et al. Macrolide resistance gene mreA of Streptococcus agalactiae encodes a flavokinase. 2001 Antimicrob. Agents Chemother. pmid:11451686
Goldstein EJ et al. In vitro activities of ABT-773, a new ketolide, against aerobic and anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis. 2001 Antimicrob. Agents Chemother. pmid:11451698
Jacobs JA et al. Prevalence of macrolide resistance genes in clinical isolates of the Streptococcus anginosus ("S. milleri") group. 2001 Antimicrob. Agents Chemother. pmid:11451701
De Mouy D et al. Antibiotic susceptibility and mechanisms of erythromycin resistance in clinical isolates of Streptococcus agalactiae: French multicenter study. 2001 Antimicrob. Agents Chemother. pmid:11451709
Yamada G et al. Centrilobular nodules correlate with air trapping in diffuse panbronchiolitis during erythromycin therapy. 2001 Chest pmid:11451838
Facinelli B et al. Association between erythromycin resistance and ability to enter human respiratory cells in group A streptococci. 2001 Lancet pmid:11454374
Piessevaux H et al. Perception of changes in wall tension of the proximal stomach in humans. 2001 Gut pmid:11454795
Ose L [Encephalitis associated with mycoplasma pneumoniae infection in children]. 1975 Tidsskr. Nor. Laegeforen. pmid:1145545
Cha S et al. The emergence of erythromycin-resistant Streptococcus pyogenes in Seoul, Korea. 2001 J. Infect. Chemother. pmid:11455497