erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (20)
- J. Antimicrob. Chemother. (9)
- Drug Metab. Dispos. (2)
- Others (20)
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Varga J and Fodor L | Biochemical characteristics, serogroup distribution, antibiotic susceptibility and age-related significance of Campylobacter strains causing diarrhoea in humans in Hungary. | 1998 | Zentralbl. Bakteriol. | pmid:9728406 |
| Kantola T et al. | Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. | 1998 | Clin. Pharmacol. Ther. | pmid:9728898 |
| Edelstein PH | Antimicrobial chemotherapy for Legionnaires disease: time for a change. | 1998 | Ann. Intern. Med. | pmid:9729189 |
| Xu QW et al. | Effect of the prokinetic agent, erythromycin, in the Richardson ground squirrel model of cholesterol gallstone disease. | 1998 | Hepatology | pmid:9731548 |
| Eckardt L et al. | Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin. | 1998 | J. Cardiovasc. Pharmacol. | pmid:9733356 |
| McDougal LK et al. | Detection of Tn917-like sequences within a Tn916-like conjugative transposon (Tn3872) in erythromycin-resistant isolates of Streptococcus pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9736555 |
| Koch CL et al. | In-vitro antibiotic susceptibility and molecular analysis of anaerobic bacteria isolated in Cape Town, South Africa. | 1998 | J. Antimicrob. Chemother. | pmid:9738844 |
| Barg N | Comparison of four antibiotics in a murine model of necrotizing cutaneous infections caused by toxigenic Streptococcus pyogenes and Staphylococcus aureus. | 1998 | J. Antimicrob. Chemother. | pmid:9738847 |
| Hargreaves CA et al. | Effects of co-trimoxazole, erythromycin, amoxycillin, tetracycline and chloroquine on sperm function in vitro. | 1998 | Hum. Reprod. | pmid:9740442 |
| Tsang KW et al. | Clinical profiles of Chinese patients with diffuse panbronchiolitis. | 1998 | Thorax | pmid:9741370 |
| Somkuti GA et al. | Molecular characterization of the erythromycin resistance plasmid pPV142 from Staphylococcus simulans. | 1998 | FEMS Microbiol. Lett. | pmid:9742700 |
| Igari J et al. | [Antimicrobial activities of roxithromycin against recently obtained clinical isolates]. | 1997 | Jpn J Antibiot | pmid:9743909 |
| Hamáková K and Danda J | [Treatment of syphilis with other antibiotics than penicillin (author's transl)]. | 1976 | Cesk Dermatol | pmid:975270 |
| Esposito S et al. | Erythromycin resistance in group A beta hemolytic streptococcus. | 1998 Nov-Dec | Chemotherapy | pmid:9755297 |
| Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |
| Barbanoj MJ et al. | Buspirone plasma concentrations. | 1998 | Clin. Pharmacol. Ther. | pmid:9757159 |
| Hoppe JE and Paulus T | Comparison of three media for agar dilution susceptibility testing of Bordetella pertussis using six antibiotics. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758277 |
| GarcÃa-de-Lomas J et al. | A comparative study on the efficacy of the new quinolone alatrofloxacin in the treatment of experimental legionellosis in guinea pigs. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758285 |
| Nion I et al. | [Role of intravenous erythromycin in the preparation for endoscopy in case of upper digestive hemorrhage]. | 1998 | Gastroenterol. Clin. Biol. | pmid:9762296 |
| Gené A et al. | [Antibiotic sensitivity of Streptococcus pyogenes in pediatrics]. | 1998 Jun-Jul | Enferm. Infecc. Microbiol. Clin. | pmid:9763744 |