erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Skin Diseases, Bacterial D017192 8 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Leprosy D007918 8 associated lipids
Osteolysis D010014 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Arthralgia D018771 8 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Bacteriuria D001437 7 associated lipids
Paresthesia D010292 7 associated lipids
Nausea D009325 7 associated lipids
Folliculitis D005499 7 associated lipids
Gonorrhea D006069 7 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Lipidoses D008064 7 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Stomach Diseases D013272 7 associated lipids
Chronic Disease D002908 7 associated lipids
Conjunctivitis D003231 7 associated lipids
Tachycardia D013610 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Bronchiectasis D001987 7 associated lipids
Bone Resorption D001862 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Endometritis D004716 6 associated lipids
Trisomy D014314 6 associated lipids
Skin Ulcer D012883 6 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Xerostomia D014987 6 associated lipids
Nocardia Infections D009617 6 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Pericarditis D010493 6 associated lipids
Bronchiolitis D001988 6 associated lipids
Whooping Cough D014917 6 associated lipids
Liver Abscess D008100 6 associated lipids
Thromboembolism D013923 6 associated lipids
Syphilis D013587 6 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Utsunomiya S et al. Critical residues in the transmembrane helical bundle domains of the human motilin receptor for erythromycin binding and activity. 2013 Regul. Pept. pmid:23142315
Li YJ et al. EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: importance in IL-8 transcription. 2013 Pulm Pharmacol Ther pmid:23291319
Di Salvo A et al. Pharmacokinetics and residue depletion of erythromycin in rainbow trout Oncorhynchus mykiss (Walbaum). 2013 J. Fish Dis. pmid:24118016
Kelley C et al. Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. 2013 Eur J Med Chem pmid:23314053
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
Basak R and Bandyopadhyay R Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH. 2013 Langmuir pmid:23472840
Hinarejos P et al. The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. 2013 J Bone Joint Surg Am pmid:23636182
Roberts DW What is the role of antibiotic-containing cement in total knee arthroplasty? 2013 J Bone Joint Surg Am pmid:23636201
Marcellin E et al. Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. 2013 BMC Genomics pmid:23324121
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Lian W et al. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. 2012 Oct-Dec Biosens Bioelectron pmid:22683249
Hapa A et al. Childhood pityriasis lichenoides and oral erythromycin. 2012 Nov-Dec Pediatr Dermatol pmid:22639857
Asai N et al. A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. 2012 Nov-Dec J Bras Pneumol pmid:23288130
Clementson B and Smidt AC Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. 2012 May-Jun Pediatr Dermatol pmid:22122785
Kuhn M et al. Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. 2012 Jul-Aug Berl. Munch. Tierarztl. Wochenschr. pmid:22919930
Jiang RS et al. Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. 2012 Jul-Aug Am J Rhinol Allergy pmid:22801017
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Amatya A et al. Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. 2012 Jan-Mar Kathmandu Univ Med J (KUMJ) pmid:22971864
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Pehr K Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. 2012 Jan-Feb J Cutan Med Surg pmid:22417996
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Popowska M et al. Influence of soil use on prevalence of tetracycline, streptomycin, and erythromycin resistance and associated resistance genes. 2012 Antimicrob. Agents Chemother. pmid:22203596
Wang L et al. Persistence of resistance to erythromycin and tetracycline in swine manure during simulated composting and lagoon treatments. 2012 Microb. Ecol. pmid:21811793
Oo C and Shah B Does erythromycin have anti-inflammatory effects independent of its antimicrobial action? 2012 J Clin Pharmacol pmid:21868717
März A et al. Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. 2012 Anal Bioanal Chem pmid:21822777
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Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. 2012 Prescrire Int pmid:22852287
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