erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hematuria D006417 13 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Hemolysis D006461 131 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpes Genitalis D006558 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hypersplenism D006971 3 associated lipids
Hypertension D006973 115 associated lipids
Hypotension D007022 41 associated lipids
Hypothermia D007035 19 associated lipids
Hypoventilation D007040 2 associated lipids
Impetigo D007169 3 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Inflammation D007249 119 associated lipids
Intestinal Atresia D007409 3 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Intraoperative Complications D007431 5 associated lipids
Ischemia D007511 18 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Laryngitis D007827 5 associated lipids
Legionellosis D007876 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Leprosy D007918 8 associated lipids
Leukemia D007938 74 associated lipids
Leukemia P388 D007941 43 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lipidoses D008064 7 associated lipids
Listeriosis D008088 12 associated lipids
Liver Abscess D008100 6 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
pmid:5110814
pmid:16888699
pmid:17760348
pmid:
Sebrechts T et al. Serial Gastric Ultrasound to Evaluate Gastric Emptying After Prokinetic Therapy With Domperidone and Erythromycin in a Surgical Patient With a Full Stomach: A Case Report. 2018 A A Pract pmid:29634526
Mirza S et al. Influence of solvents on the variety of crystalline forms of erythromycin. 2003 AAPS PharmSci pmid:12866939
Mirza S et al. Crystal morphology engineering of pharmaceutical solids: tabletting performance enhancement. 2009 AAPS PharmSciTech pmid:19184449
Pignatello R et al. Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. 2011 AAPS PharmSciTech pmid:21479751
Petrakis IE et al. Hyperglycemia attenuates erythromycin-induced acceleration of solid-phase gastric emptying in healthy subjects. 2002 May-Jun Abdom Imaging pmid:12173362
Gore RM et al. Drug-induced disorders of the stomach and duodenum. 1999 Jan-Feb Abdom Imaging pmid:9933666
Wang X et al. Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. 2013 ACS Appl Mater Interfaces pmid:24150740
Leirós M et al. Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. 2014 ACS Chem Neurosci pmid:24219236
McCusker KP and Fujimori DG The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. 2012 ACS Chem. Biol. pmid:22208312
Koryakina I et al. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. 2017 ACS Chem. Biol. pmid:28103677
Sundermann U et al. Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. 2013 ACS Chem. Biol. pmid:23181268
Buchholz TJ et al. Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. 2009 ACS Chem. Biol. pmid:19146481
Kasey CM et al. Development of Transcription Factor-Based Designer Macrolide Biosensors for Metabolic Engineering and Synthetic Biology. 2018 ACS Synth Biol pmid:28950701
Tixador R et al. Preliminary results of Cytos 2 experiment. 1985 Acta Astronaut pmid:11542841
Olajuyigbe OO et al. In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. 2017 Acta Biochim. Pol. pmid:28612062
Klita S and Szafranśki P Comparison of the mechanism of action of cyclic 11,12-erythromycin A carbonate and erythromycin A. 1980 Acta Biochim. Pol. pmid:7023159