erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hematuria D006417 13 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Hemolysis D006461 131 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpes Genitalis D006558 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hypersplenism D006971 3 associated lipids
Hypertension D006973 115 associated lipids
Hypotension D007022 41 associated lipids
Hypothermia D007035 19 associated lipids
Hypoventilation D007040 2 associated lipids
Impetigo D007169 3 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Inflammation D007249 119 associated lipids
Intestinal Atresia D007409 3 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Intraoperative Complications D007431 5 associated lipids
Ischemia D007511 18 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Laryngitis D007827 5 associated lipids
Legionellosis D007876 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Leprosy D007918 8 associated lipids
Leukemia D007938 74 associated lipids
Leukemia P388 D007941 43 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lipidoses D008064 7 associated lipids
Listeriosis D008088 12 associated lipids
Liver Abscess D008100 6 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Herath SC and Poole P Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). 2013 Cochrane Database Syst Rev pmid:24288145
Liang JH and Han X Structure-activity relationships and mechanism of action of macrolides derived from erythromycin as antibacterial agents. 2013 Curr Top Med Chem pmid:24200358
Matejcek A and Goldman RD Treatment and prevention of ophthalmia neonatorum. 2013 Can Fam Physician pmid:24235191
Kamal A et al. Anti-tubercular agents. Part 8: synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazoles. 2013 Bioorg. Med. Chem. Lett. pmid:24206766
Rallis E et al. Topical 5% benzoyl peroxide and 3% erythromycin gel: experience with 191 patients with papulopustular acne. 2013 Acta Dermatovenerol Croat pmid:24183219
Sugino K et al. Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. 2013 Intern. Med. pmid:24292765
Arao M et al. Clostridium difficile colitis induced by long-term low-dosage erythromycin. 2013 Pediatr. Infect. Dis. J. pmid:24008746
Yin YD et al. [Survey of macrolide resistance in Mycoplasma pneumoniae in adult patients with community-acquired pneumonia in Beijing, China]. 2013 Zhonghua Jie He He Hu Xi Za Zhi pmid:24503430
Ansari NN et al. Treatment of chronic rhinosinusitis using erythromycin phonophoresis. 2013 Physiother Theory Pract pmid:22891948
Chen DK et al. [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. 2013 Zhonghua Yi Xue Za Zhi pmid:24548451
Lin MH et al. Penetration of erythromycin through Staphylococcus epidermidis biofilm. 2013 Chin. Med. J. pmid:23876889
Winnicka K et al. The effect of PAMAM dendrimers on the antibacterial activity of antibiotics with different water solubility. 2013 Molecules pmid:23881050
Hennenberg M et al. The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction. 2013 J. Biomed. Sci. pmid:23815815
Mu Y et al. Synergistic effects of anti-CmeA and anti-CmeB peptide nucleic acids on sensitizing Campylobacter jejuni to antibiotics. 2013 Antimicrob. Agents Chemother. pmid:23817373
González-Abad MJ and Alonso-Sanz M [Incidence and susceptibility of Campylobacter jejuni in pediatric patients: involvement in bacteremia]. 2013 Rev Esp Quimioter pmid:23817644
Sanz-Rodríguez N et al. [Accuracy of Etest method to study Campylobacter spp. susceptibility to erythromycin, ciprofloxacin and tetracycline]. 2013 Rev Esp Quimioter pmid:23817649
James GD et al. Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. 2013 Prim Care Respir J pmid:23839240
Parhi AK et al. Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. 2013 Bioorg. Med. Chem. Lett. pmid:23891185
Mu X et al. Effects of erythromycin and rifampicin on immunomodulatory gene expression and cellular function in human polymorphonuclear leukocytes. 2013 Chemotherapy pmid:24852442
Papapetropoulos N et al. Abscesses and wound infections due to Staphylococcus lugdunensis: report of 16 cases. 2013 Infection pmid:23242962
Berger A et al. Two cases of cutaneous diphtheria associated with occupational pig contact in Germany. 2013 Zoonoses Public Health pmid:23280311
Juntunen P et al. Absence of tetracycline resistance in Campylobacter coli isolates from Finnish finishing pigs treated with chlortetracycline. 2013 J. Appl. Microbiol. pmid:23282197
Mavri A and Smole Možina S Resistance to bile salts and sodium deoxycholate in macrolide- and fluoroquinolone-susceptible and resistant Campylobacter jejuni and Campylobacter coli strains. 2013 Microb. Drug Resist. pmid:23289436
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Osterman IA et al. A nascent proteome study combining click chemistry with 2DE. 2013 Proteomics pmid:23161590
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Moriya S et al. Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. 2013 Int. J. Oncol. pmid:23546223
Akiyoshi T et al. Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants. 2013 Drug Metab. Pharmacokinet. pmid:23514827
Müller W et al. German Francisella tularensis isolates from European brown hares (Lepus europaeus) reveal genetic and phenotypic diversity. 2013 BMC Microbiol. pmid:23517149
Lasnier O et al. Two cases of corneal abrasions in children exposed to liquid detergent capsules. 2013 Can. J. Ophthalmol. pmid:23561618
Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern. 2013 Indian J. Med. Res. pmid:23563381
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400
Litvinchuk AV et al. Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. 2013 Apr-May Eur. J. Cell Biol. pmid:23523087
Lynch M et al. Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. 2013 Jan-Feb Pediatr Dermatol pmid:23316718
Jiang M et al. Improved heterologous erythromycin A production through expression plasmid re-design. 2013 Jul-Aug Biotechnol. Prog. pmid:23804312
Zou X et al. Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. 2013 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:23795479
De Alwis HG et al. Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. 2013 Nov-Dec J AOAC Int pmid:24645499
Kim S and Muthusamy VR Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045591
Theivanayagam S et al. Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045593
Manchia M et al. Repeated erythromycin/codeine-induced psychotic mania. 2013 Sep-Oct Clin Neuropharmacol pmid:24045612
Chen D et al. Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. 2014 PLoS ONE pmid:25250723
Goni BW et al. Diphtheria in a 7-year-old child in north-eastern Nigeria - management in a resource-poor setting. 2014 Trop Doct pmid:24249028
Sadeghi J and Mansouri S Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman). 2014 APMIS pmid:24033803
Haworth CS et al. Long-term macrolide maintenance therapy in non-CF bronchiectasis: evidence and questions. 2014 Respir Med pmid:25301290
Zhang XF et al. Does Braun enteroenterostomy reduce delayed gastric emptying after pancreaticoduodenectomy? 2014 Medicine (Baltimore) pmid:25101987
Blattner C et al. A case of bacillary angiomatosis in a patient with pancreatic adenocarcinoma. 2014 J. Cutan. Pathol. pmid:24588271
Brenciani A et al. ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. 2014 Antimicrob. Agents Chemother. pmid:24449773
Yu ZC et al. Development of a genetic system for the deep-sea psychrophilic bacterium Pseudoalteromonas sp. SM9913. 2014 Microb. Cell Fact. pmid:24450434
Barnes P and Chauhan M Chancroid - desperate patient makes own diagnosis. 2014 Int J STD AIDS pmid:24535694
Barbosa TM et al. A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. 2014 PLoS ONE pmid:25548909
Hudson BH and Zaher HS Ribosomes left in the dust: diverse strategies for Peptide-mediated translation stalling. 2014 Mol. Cell pmid:25514181
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Belén Flórez A et al. Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. 2014 Biomed Res Int pmid:25302306
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Katayama Y et al. Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. 2014 Brain Res. pmid:25264351
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Kemp MW et al. Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. 2014 Am. J. Obstet. Gynecol. pmid:24589547
Zhang Y et al. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721407
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Kawaguchiya M et al. Serotype distribution and susceptibility to penicillin and erythromycin among noninvasive or colonization isolates of Streptococcus pneumoniae in northern Japan: a cross-sectional study in the pre-PCV7 routine immunization period. 2014 Microb. Drug Resist. pmid:24766085
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Boleda MR et al. Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. 2014 Environ Sci Pollut Res Int pmid:24756682
Nilsson MF and Webster WS Effects of macrolide antibiotics on rat embryonic heart function in vitro. 2014 Birth Defects Res. B Dev. Reprod. Toxicol. pmid:24753334
Murphree CA et al. Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. 2014 Curr. Microbiol. pmid:24748439
Sakamoto N et al. Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. 2014 Intern. Med. pmid:24739609
Szemraj M et al. Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. 2014 Microb. Drug Resist. pmid:24735183
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Yosida M et al. Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion. 2014 Diabetes pmid:24824430
Thumu SC and Halami PM Phenotypic expression, molecular characterization and transferability of erythromycin resistance genes in Enterococcus spp. isolated from naturally fermented food. 2014 J. Appl. Microbiol. pmid:24206069
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Zheng PX et al. Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. 2014 Clin. Microbiol. Infect. pmid:24118239
Singh P et al. Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. 2014 Fundam Clin Pharmacol pmid:24117516
Dalbøge CS et al. Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. 2014 J. Cyst. Fibros. pmid:24035278
Di Salvo A et al. Pharmacokinetics and residue depletion of erythromycin in gilthead sea bream Sparus aurata L. after oral administration. 2014 J. Fish Dis. pmid:23992037
Rodríguez-Gutiérrez R et al. Herpes zoster ophthalmicus masked by hymenoptera stings. 2014 Am. J. Med. Sci. pmid:23085675