erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Uglov FG et al. | [The use of antibiotics in surgical practice]. | 1967 | Vestn. Khir. Im. I. I. Grek. | pmid:4304565 |
Afanas'ev BA | [Erythromycin in the treatment of gonorrhea in women]. | 1967 | Vestn Dermatol Venerol | pmid:5611849 |
Hawiger J and Jeljaszewicz J | Antibiotic sensitivity of Micrococcus radiodurans. | 1967 | Appl Microbiol | pmid:4166078 |
Linquette M and Decoulx M | [Clinical experimentation with an antibiotic: erythromycin stearate]. | 1967 | Lille Med | pmid:5619706 |
BoÄko GF et al. | [Clinical course and treatment of biliary tract lambliasis]. | 1967 | Vrach Delo | pmid:5621415 |
Friend PL and Slade HD | Effect of resistance to chloramphenicol on bacteriophage sensitivity of group A streptococci. | 1967 | J. Virol. | pmid:5623958 |
Takahashi T | [Fundamental studies on the usefulness of milk acid bacteria for the human body. II. Experiments on L. acidophilus passage through mice]. | 1967 | Zasshi Tokyo Ika Daigaku | pmid:5626035 |
Blinov NO and Khokhlov AS | [Paper chromatography and electrophoresis in the study of the transformation of antibiotics in the human and animal body]. | 1967 | Antibiotiki | pmid:4874768 |
Maichuk IuF | [Antibiotics in polyvinyl alcohol film for treatment of infectious eye diseases]. | 1967 | Antibiotiki | pmid:4874770 |
Wagner JG and Metzler CM | Estimation of rate constants for absorption and elimination from blood concentration data. | 1967 | J Pharm Sci | pmid:6032790 |
Levitov MM and Brinberg SL | [Physiology of antibiotic-producing microorganisms and the process of biosynthesis of antibiotics]. | 1967 | Antibiotiki | pmid:4875265 |
Popovici GG et al. | The influence of some antibiotics on uterine motor activity in the guinea pig. | 1967 | Arch Int Pharmacodyn Ther | pmid:6034322 |
Kuzel NR and Coffey HF | Automated analysis of erythromycin. | 1967 | J Pharm Sci | pmid:6034553 |
Richmond MH | A second regulatory region involved in penicillinase synthesis in Staphylococcus aureus. | 1967 | J. Mol. Biol. | pmid:6034780 |
Celmer WD and Ebringer L | Effects of certain O-acyl derivatives of oleandomycin and erythromycin on chloroplasts of Euglena gracilis. | 1967 | J. Protozool. | pmid:6038034 |
Perun TJ | Chemistry of erythronolide B. Acid-catalyzed transformations of the aglycone of erythromycin B. | 1967 | J. Org. Chem. | pmid:6046179 |
Djokić S and Tamburasĕv Z | Erythromycin study: 9-amino-3-O-cladinosyl-5-O-desosaminyl-6,11,12-tryhydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide. | 1967 | Tetrahedron Lett. | pmid:6047192 |
Martin JR and Rosenbrook W | Studies on the biosynthesis of the erythromycins. II. Isolation and structure of a biosynthetic intermediate, 6-deoxyerythronolide B. | 1967 | Biochemistry | pmid:6047629 |
Fabre J | [Drugs and renal function]. | 1967 | Helv Med Acta Suppl | pmid:5286305 |
Pines A | Four trials of antibiotics in patients with chronic mucopurulent bronchitis. | 1967 | Postgrad Med J | pmid:4962745 |
Scanlon RT and Nemes JL | Efficacy and acceptability of erythromycin oral preparations for pediatric practice. | 1967 | Med Ann Dist Columbia | pmid:5232908 |
Myers WH | A comparative trial of Erythroped versus penicillin V. | 1967 | Br J Clin Pract | pmid:4963172 |
Markham JG and Markham NP | Changing characters of the hospital staphylococcus. | 1967 | N. Z. Med. J. | pmid:5233364 |
Ronald A et al. | Antibiotic susceptibilities of Neisseria Gonorrheae isolates. | 1967 | Northwest Med | pmid:4963188 |
Nichols JT et al. | An allergic response to a single dose of erythromycin. Report of a case. | 1967 | Oral Surg. Oral Med. Oral Pathol. | pmid:5233378 |
Wilhelm JM and Corcoran JW | Antibiotic glycosides. VI. Definition of the 50s ribosomal subunit of Bacillus subtilis 168 as a major determinant of sensitivity to erythromycin A. | 1967 | Biochemistry | pmid:4963466 |
Dyke KG and Richmond MH | Occurrence of various types of penicillinase plasmid among 'hospital' staphylococci. | 1967 | J. Clin. Pathol. | pmid:6016889 |
Tourtellotte ME et al. | Protein synthesis in mycoplasma. | 1967 | Ann. N. Y. Acad. Sci. | pmid:5233752 |
Shepard MC | Cultivation and properties of T-strains of mycoplasma associated with nongonococcal urethritis. | 1967 | Ann. N. Y. Acad. Sci. | pmid:5233783 |
Stelińska A et al. | [Observations on the effectiveness of erythromycin activity on the bacterial flora of dental origin]. | 1967 | Czas Stomatol | pmid:5234368 |
Merklen FP and Renoux M | [Antibiotics other than penicillin in the treatment of syphilis]. | 1967 | Rev Fr Odontostomatol | pmid:5235420 |
Kalowski M and Romankiewicz GE | [Effect of penicillin and erythromycin on the inhibition of rampant dental caries in golden hamsters]. | 1967 | Czas Stomatol | pmid:5235543 |
Dechaume M et al. | [Clinical stomatologic studies of erythromycine stearate and erythromycine ethyl-succinate]. | 1967 | Inf Dent | pmid:5235751 |
Haraguchi I et al. | [Clinico-pathological study on the effect of erythromycin on pulp tissue]. | 1967 | Shikwa Gakuho | pmid:5236258 |
Takei M et al. | [Studies on the mixed culture of Candida and Lactobacillus. 3. Influences of the antibiotics (EM and TM)]. | 1967 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5236280 |
Molan PC and Hartles RL | The source of glycolytic activity in human saliva. | 1967 | Arch. Oral Biol. | pmid:5237340 |
Cernea P and Devien CV | [Therapeutic value of a new comined antibiotic therapy]. | 1967 | Rev Fr Odontostomatol | pmid:5238749 |
Sugiyama H | [Experimental studies on control of dental caries. 1. Preventive effect of Erythromycin]. | 1967 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5244796 |
Kislak JW | Type 6 pneumococcus resistant to erythromycin and lincomycin. | 1967 | N. Engl. J. Med. | pmid:4381364 |
Green GR et al. | Treatment of bacterial endocarditis in patients with penicillin hypersensitivity. | 1967 | Ann. Intern. Med. | pmid:4382501 |
Zagar Z | [Antimicrobial therapy and public health]. | 1967 | Wien. Klin. Wochenschr. | pmid:5185251 |
Dillon ML and Bowling KA | Effect of antibiotics on wound and stool cultures. Comparison of intravenous terramycin with other antibiotics. | 1967 | Am. J. Surg. | pmid:5334435 |
Smith CB et al. | Inactivated Mycoplasma pneumoniae vaccine. Evaluation in volunteers. | 1967 | JAMA | pmid:5334595 |
Prokhorov BS | [Sensitivity to antibiotics and phagolytic properties of staphylococcal strains, isolated from patients]. | 1967 | Antibiotiki | pmid:5187281 |
Shneerson AN | [On the heterogenicity of the population of clinical strains of Staphylococci in relation to their sensitivity to polysynthetic penicillins and macrolide antibiotics]. | 1967 | Antibiotiki | pmid:5187299 |
Jensen K | [Combination therapy with antibacterial chemotherapeutic agents in staphylococcal infections]. | 1967 | Ugeskr. Laeg. | pmid:5187979 |
Slotkin RI et al. | The effect of antibiotics on Mycoplasma pneumoniae in vitro and in vivo. | 1967 | Am. J. Epidemiol. | pmid:5006447 |
Sugano T et al. | [Results in the combined use of nalidixic acid with other drugs for bacillary dysentery]. | 1967 | Nihon Densenbyo Gakkai Zasshi | pmid:4968896 |
Jedlicková Z | [Contribution to the study of the sensitivity of staphylococci toward so-called anti-staphylococcal-antibiotics]. | 1967 | Arzneimittelforschung | pmid:4971496 |
Legler F | [Present resistance status of Staphylococcus aureus under specific consideration of the antibiotics virgimycia, cephalothin and fusidic acid]. | 1967 | Arzneimittelforschung | pmid:4974419 |
Hejzlar M et al. | Cephaloridine. II. The effect of cephaloridine on experimental model infections. | 1967 | J Hyg Epidemiol Microbiol Immunol | pmid:5629908 |
Kaltiala EH et al. | Subchronic toxicity of some erythromycin compounds in rats. | 1967 | Acta Pharmacol Toxicol (Copenh) | pmid:5630681 |
Larson RH et al. | The interaction of diet and microflora in experimental caries in the rat. | 1967 | Arch. Oral Biol. | pmid:5228613 |
Heydenreich A | [Intraocular application of antibiotics]. | 1967 | Klin Monbl Augenheilkd | pmid:5586135 |
Nussbaumer PA | [A contribution to the study of erythromycin by means of thin-layer chromatography. 1. Stability in aquenous medium]. | 1967 | Pharm Acta Helv | pmid:5586792 |
Voiculescu M et al. | [Sensitivity of beta-hemolytic streptococcus, group A, isolated from streptococcal infections, to different antibiotics and sulfonamides]. | 1967 | Schweiz Med Wochenschr | pmid:5587438 |
Barbier P et al. | [Progressive experimental biliary obstruction. IV. Biliary concentration of antibiotics]. | 1967 | C. R. Seances Soc. Biol. Fil. | pmid:4234166 |
Hughes WT and Wan RT | Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. | 1967 | Am. J. Dis. Child. | pmid:4290285 |
Smits H and Freedman LR | Prolonged venous catheterization as a cause of sepsis. | 1967 | N. Engl. J. Med. | pmid:4290392 |
Halprin KM | Diagnosis with Wood's light. Tinea capitis and erythrasma. | 1967 | JAMA | pmid:6071300 |
Zegarelli EV et al. | Discoloration of the teeth in a 24-year-old patient with cystic fibrosis of the pancreas not primarily associated with tetracycline therapy. Report of a case. | 1967 | Oral Surg. Oral Med. Oral Pathol. | pmid:4291199 |
Williams ST | Sensitivity of streptomycetes to antibiotics as a taxonomic character. | 1967 | J. Gen. Microbiol. | pmid:4291590 |
Sterner G et al. | A comparative trial of cephaloridine and erythromycin in hospitalized pneumonic patients. | 1967 | Postgrad Med J | pmid:4861117 |
Clinical useful antimicrobial agents. General considerations concerning chloramphenicol, erythromycin and allied drugs, the polymyxins, bacitracin, vancomycin, ristocetin, cycloserine, the cephalosporins, the chemotherapeutic drugs and the antimycotic drugs. | 1967 | Postgrad Med | pmid:4293380 | |
Smith CB et al. | Mycoplasma pneumoniae infections in volunteers. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4861142 |
Clinically useful antimicrobial agents. Dosage and mode of administration. | 1967 | Postgrad Med | pmid:4293381 | |
Breitfellner G | [On the question of penicillin resistence]. | 1967 | Chemotherapy | pmid:4861270 |
Clinically useful antimicrobial agents. Untoward reactions. | 1967 | Postgrad Med | pmid:4293382 | |
Roberts DS | Chemotherapy of epidermal infection with Dermatophilus congolensis. | 1967 | J. Comp. Pathol. | pmid:4166506 |
Gjessing J | Bacterial growth in the dialysate fluid and the reaction of peritoneum to peritoneal dialysis. | 1967 | Acta Med Scand | pmid:4861521 |
Finegold SM et al. | Antibiotic susceptibility patterns as aids in classification and characterization of gram-negative anaerobic bacilli. | 1967 | J. Bacteriol. | pmid:4293666 |
Godzeski CW et al. | The interaction of antibiotics, bacteria and the bacterial L-phase in vivo. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4167700 |
Parnas J et al. | [Clinical and microbiological studies on macrocycline]. | 1967 | Pol Tyg Lek | pmid:4862917 |
Cole BC et al. | Characterization of mycoplasma strains from cats. | 1967 | J. Bacteriol. | pmid:4168314 |
Mao JC | The stoichiometry of erythromycin binding to ribosomal particles of Staphylococcus aureus. | 1967 | Biochem. Pharmacol. | pmid:6075404 |
Cooper RG and Gibbs MH | The antibiotic sensitivity of Bordetella in South Australia. | 1967 | Med. J. Aust. | pmid:4295245 |
Pullen H et al. | Hypersensitivity reactions to antibacterial drugs in infectious mononucleosis. | 1967 | Lancet | pmid:4168380 |
von Graevenitz A | Sensitivity studies on Serratia strains from clinical specimens. | 1967 | Chemotherapy | pmid:4863818 |
Villaveces JW | Food emulsion therapy: an adverse reaction. | 1967 | Ann Allergy | pmid:6077385 |
Kotula Z and Kamińska A | [Use of paper electrophoresis and thin layer chromatography on talc for erythromycin distribution]. | 1967 | Med Dosw Mikrobiol | pmid:6079142 |
Ozawa A | [On the sensitivity of clinically isolated bacterial strains to aminobenzyl and methylphenylisoxazolyl penicillins, with special reference to urinary tract and bile infections]. | 1967 | J Antibiot B | pmid:4866094 |
Bourse R and Monnier J | [Effect of rythromycin on the growth of "dissociated resistant" Staph. aureus in bacteriostasis from another macrolide or a related antibiotic]. | 1967 | Ann Inst Pasteur (Paris) | pmid:6079710 |
Linnane AW and Stewart PR | The inhibition of chlorophyll formation in Euglena by antibiotics which inhibit bacterial and mitochondrial protein synthesis. | 1967 | Biochem. Biophys. Res. Commun. | pmid:5298473 |
Satgé P et al. | [Generalized infections by Candida albicans in children (apropos of 17 cases)]. | 1967 | Sem Hop | pmid:4296493 |
Arai S et al. | Effect of antibiotics on the growth of various strains of Mycoplasma. | 1967 | J. Antibiot. | pmid:4170543 |
Shikata T et al. | [Intraperitoneal administration of erythromycin glucoheptonate and 5-methyl-3-sulfanilamidoisoxazole and peritoneal adhesion]. | 1967 | J Antibiot B | pmid:5299960 |
Kharitonova AM | [On the nephrotic action of antibiotics]. | 1967 | Antibiotiki | pmid:4171895 |
Medeiros J et al. | [A-16535 in the treatment of chronic intestinal amebiasis]. | 1967 | Hospital (Rio J) | pmid:5302541 |
Mehta BM et al. | Evidence of genetic transformation in Streptococcus faecium var. durans (SF-O). | 1967 | J. Bacteriol. | pmid:6051354 |
Golenia A and Rafińska J | [Contribution to the treatment of staphylococcal pericarditis]. | 1967 | Pediatr Pol | pmid:6052305 |
Treatment of atypical pneumonia. | 1967 | Med Lett Drugs Ther | pmid:6052695 | |
Armstrong BK and Curnow DH | The effect of streptomycin and erythromycin on vitamin B12 nutrition in rats in which coprophagy was prevented. | 1967 | Br. J. Nutr. | pmid:6052871 |
Manchester KL | Effects of antibiotics of protein synthesis in muscle and implications with regard to the action of insulin. | 1967 | Nature | pmid:6053821 |
Schiatti P et al. | Biliary excretion rate of semisynthetic rifamycins in the rat. | 1967 | Chemotherapy | pmid:6055273 |
Schuster W | [On the length of resorption of pneumonia infiltration under antibiotic therapy]. | 1967 | Dtsch. Med. Wochenschr. | pmid:6060872 |
Chernomordik AB | [Synergistic action of antibiotics on Bacillus pyocianaeus]. | 1967 | Antibiotiki | pmid:4300088 |
Lantos J | Change in the phage type of Staphylococcus aureus as a result of lysogenizatio. | 1967 | Acta Microbiol Acad Sci Hung | pmid:4300285 |
DoutlÃk S et al. | Electroencephalographic changes after intravenous administration of antibiotics. | 1967 | Arzneimittelforschung | pmid:4300334 |
von Wasielewski E and Schütze E | [Treatment with antibiotic agents with special reference to their relation to otorhinolaryngology]. | 1967 | Arch Klin Exp Ohren Nasen Kehlkopfheilkd | pmid:4300371 |
Yousef RT et al. | An agar disc method for testing the sensitivity of microorganisms to antibiotics. | 1967 | Arzneimittelforschung | pmid:4303563 |