erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hematuria D006417 13 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Hemolysis D006461 131 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpes Genitalis D006558 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hypersplenism D006971 3 associated lipids
Hypertension D006973 115 associated lipids
Hypotension D007022 41 associated lipids
Hypothermia D007035 19 associated lipids
Hypoventilation D007040 2 associated lipids
Impetigo D007169 3 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Inflammation D007249 119 associated lipids
Intestinal Atresia D007409 3 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Intraoperative Complications D007431 5 associated lipids
Ischemia D007511 18 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Laryngitis D007827 5 associated lipids
Legionellosis D007876 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Leprosy D007918 8 associated lipids
Leukemia D007938 74 associated lipids
Leukemia P388 D007941 43 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lipidoses D008064 7 associated lipids
Listeriosis D008088 12 associated lipids
Liver Abscess D008100 6 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Ramirez B and Richter JE Review article: promotility drugs in the treatment of gastro-oesophageal reflux disease. 1993 Aliment. Pharmacol. Ther. pmid:8094981
Catnach SM et al. Dose-dependent stimulation of gallbladder contraction by intravenous erythromycin in man. 1993 Aliment. Pharmacol. Ther. pmid:8439638
Verhagen MA et al. Effects of a new motilide, ABT-229, on gastric emptying and postprandial antroduodenal motility in healthy volunteers. 1997 Aliment. Pharmacol. Ther. pmid:9663833
Haans JJ and Masclee AA Review article: The diagnosis and management of gastroparesis. 2007 Aliment. Pharmacol. Ther. pmid:18081647
McCallum RW and Cynshi O Clinical trial: effect of mitemcinal (a motilin agonist) on gastric emptying in patients with gastroparesis - a randomized, multicentre, placebo-controlled study. 2007 Aliment. Pharmacol. Ther. pmid:17894654
Winstead NS and Wilcox CM Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage: a cost-effectiveness analysis. 2007 Aliment. Pharmacol. Ther. pmid:17848180
Bell GD et al. Short report: omeprazole plus antibiotic combinations for the eradication of metronidazole-resistant Helicobacter pylori. 1992 Aliment. Pharmacol. Ther. pmid:1486161
Brand RM et al. Transdermal delivery of erythromycin lactobionate--implications for the therapy of gastroparesis. 1997 Aliment. Pharmacol. Ther. pmid:9218087
Annese V et al. Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus. 1997 Aliment. Pharmacol. Ther. pmid:9218089
van Erpecum KJ et al. Review article: agents affecting gall-bladder motility--role in treatment and prevention of gallstones. 2000 Aliment. Pharmacol. Ther. pmid:10903008
Chiba T et al. Motilides accelerate regional gastrointestinal transit in the dog. 2000 Aliment. Pharmacol. Ther. pmid:10886053
Landry C et al. Could oral erythromycin optimize high energy continuous enteral nutrition? 1996 Aliment. Pharmacol. Ther. pmid:8971296
Ehrenpreis ED et al. Which form of erythromycin should be used to treat gastroparesis? A pharmacokinetic analysis. 1998 Aliment. Pharmacol. Ther. pmid:9690728
Osato MS et al. Comparative efficacy of new investigational agents against Helicobacter pylori. 2001 Aliment. Pharmacol. Ther. pmid:11284777
Medhus AW et al. Low-dose intravenous erythromycin: effects on postprandial and fasting motility of the small bowel. 2000 Aliment. Pharmacol. Ther. pmid:10651665
Curry JI et al. Review article: erythromycin as a prokinetic agent in infants and children. 2001 Aliment. Pharmacol. Ther. pmid:11328252
Kendall BJ et al. The effect of intravenous erythromycin on solid meal gastric emptying in patients with chronic symptomatic post-vagotomy-antrectomy gastroparesis. 1997 Aliment. Pharmacol. Ther. pmid:9146779
Boecxstaens V et al. Modulation of the postprandial acid and bile pockets at the gastro-oesophageal junction by drugs that affect gastric motility. 2011 Aliment. Pharmacol. Ther. pmid:21517922
Laine L et al. Prospective evaluation of the macrolide antibiotic dirithromycin for the treatment of Helicobacter pylori. 1996 Aliment. Pharmacol. Ther. pmid:8791949
Mosonyi L et al. [Infectious and neoplastic complications in rheumatoid arthritis]. 1974-1975 Allerg Immunol (Leipz) pmid:4282826