erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Biberfeld G and Sterner G | A study of Mycoplasma pneumoniae infections in families. | 1969 | Scand. J. Infect. Dis. | pmid:4938476 |
Hill HR et al. | Food-borne epidemic of streptoccal pharyngitis at the United States Air Force Academy. | 1969 | N. Engl. J. Med. | pmid:4887164 |
Teraoka H et al. | The comparative study on the effects of chloramphenicol, erythromycin and lincomycin on polylysine synthesis in an Escherichia coli cell-free system. | 1969 | Biochim. Biophys. Acta | pmid:4887382 |
Murphy JE | Clinical experience in general practice of a new formulation of erythromycin estolate. | 1969 | Br J Clin Pract | pmid:4887677 |
Demarco PV | NMR study of some erythromycin aglycones. A conformational and configurational analysis. | 1969 | J. Antibiot. | pmid:5346042 |
Sprunt K et al. | Oral antibiotics in patients with heart disease: case report of child facing oropharyngeal surgery with oropharyngeal viridans streptococci resistant to penicillin and, following oral erythromycin therapy, to penicillin, erythromycin, and lincomycin. | 1969 | Pediatrics | pmid:5191724 |
Clark H | An evaluation of antibiotic prophylaxis in cardiac catheterization. | 1969 | Am. Heart J. | pmid:5192402 |
Guggenheim B et al. | [Modifications of the oral bacterial flora and their influence on dental caries in the rat. 3. The cariogenicity of an erythromycin-resistant strain of Streptococcus mutans compared to its non-resistant parent strain]. | 1969 | Helv Odontol Acta | pmid:5192679 |
Voropaeva SD | [Multiple resistance of staphylococci, isolated from the patients]. | 1969 | Antibiotiki | pmid:5192737 |
Jessen O et al. | Changing staphylococci and staphylococcal infections. A ten-year study of bacteria and cases of bacteremia. | 1969 | N. Engl. J. Med. | pmid:5194719 |
Bals MG and FilipescÅ S | The antistaphylococcal activity of Rifampicin. | 1969 | Arzneimittelforschung | pmid:5194845 |
Annear DI and Grubb WB | Sponaneous loss of resistance to kanamycin and other antibiotics in methicillin-resistant cultures of Staphylococcus aureus. | 1969 | Med. J. Aust. | pmid:5196123 |
Davey PJ et al. | The intracellular site of formation of the mitochondrial protein synthetic system. | 1969 | Biochem. Biophys. Res. Commun. | pmid:5796754 |
Harwick HJ and Fekety FR | The antibiotic susceptibility of Mycoplasma hominis. | 1969 | J. Clin. Pathol. | pmid:5798637 |
Saccani F and Pitrolo G | [Separation and identification of various antibiotics in complex mixtures. IV]. | 1969 | Boll Chim Farm | pmid:5354280 |
Bialski R | [Erythromycin stearate in "single dose" in the treatment of acute masculine gonococcal urethritis]. | 1969 | Rev Bras Med | pmid:5800220 |
Mayon-White RT and Wilkinson DS | Dermatitis herpetiformis occurring in a case of controlled coeliac disease. | 1969 | Br. J. Dermatol. | pmid:5801338 |
Caruso F | [Treatment of sepsis in infants with an association of erythromycin and chloramphenicol]. | 1969 | Clin Ter | pmid:5355892 |
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Ruczaj D | [Countercurrent distribution of compounds present in cultures of Streptomyces sp. 64-575]. | 1969 | Acta Pol Pharm | pmid:5356252 |
Tardrew PL et al. | Antibacterial activity of 2'-esters of erythromycin. | 1969 | Appl Microbiol | pmid:5807154 |
Abou-Zeid AA and el-Gamal AA | Erythromycin fermentation by Streptomyces erythreus. | 1969 | Indian J. Exp. Biol. | pmid:5359105 |
Bezborodov AM et al. | [Coenzyme A content of the mycelium of antibiotic-producing Actinomycetes]. | 1969 | Antibiotiki | pmid:5808677 |
Rozenfel'd GS et al. | [Study of composition of preparations of erythromycin-base]. | 1969 | Antibiotiki | pmid:5361827 |
Bourse R et al. | [The effect of erythromycin plus lincomycin association on renal staphylococcia in mice induced by "dissociated resistant" Staphylococcus aureus]. | 1969 | Ann Inst Pasteur (Paris) | pmid:5363514 |
Lie JT et al. | Effect of antimicrobial agents on the Euglena method of serum vitamin B12 assay. | 1969 | J. Clin. Pathol. | pmid:5364439 |
Nakahara T et al. | [Effect of drug administration on the child with progressive muscular dystrophy]. | 1969 | Iryo | pmid:5364983 |
Bebe M | [Therapeutic indications in staphylococcal pleursy and pneumonia. 114 cases]. | 1969 | Ann Pediatr (Paris) | pmid:5365506 |
Beale GH | A note on the inheritance of erythromycin-resistance in Paramecium aurelia. | 1969 | Genet. Res. | pmid:5367381 |
Grieco MH | Hypersensitivity abdominal pain induced by erythromycin propionate estolate. | 1969 | Med Times | pmid:5763354 |
A second look at lincomycin (lincocin). | 1969 | Med Lett Drugs Ther | pmid:5368405 | |
Koroleva VG et al. | [Effect of acid protective coating on absorption of erythromycin at oral administration]. | 1969 | Antibiotiki | pmid:5371175 |
Stewart SM et al. | In-vitro sensitivity of strains of mycoplasmas from human sources to antibiotics and to sodium aurothiomalate and tylosin tartrate. | 1969 | J. Med. Microbiol. | pmid:5206769 |
Smith DO and Osick P | Erythromycin in the treatment of acute gonococcal urethritis in males. | 1969 | Curr Ther Res Clin Exp | pmid:4973849 |
Iwamoto HK and Brennan WR | The effect of demeclocycline, methacycline, and erythromycin on tooth color in the rat. | 1969 | Toxicol. Appl. Pharmacol. | pmid:4975609 |
Wiersum J et al. | A comparison of erythromycin and methacycline in the treatment of common bacterial infections. | 1969 | Curr Ther Res Clin Exp | pmid:4976333 |
Bordácová J and Výmola F | [Sensitivity of Corynebacterium acnes toward antibiotics]. | 1969 | Arzneimittelforschung | pmid:4976652 |
Nodari R | [The use of erythromycin in bacterial infections in infants and children]. | 1969 | Minerva Pediatr. | pmid:5403320 |
Guidi G et al. | [Current therapeutic use of erythromycin. Treatment and tolerance in a group of 132 subjects]. | 1969 | Clin Ter | pmid:5405075 |
Mao JC and Putterman M | The intermolecular complex of erythromycin and ribosome. | 1969 | J. Mol. Biol. | pmid:5406454 |
Lagert IK et al. | [Antibiotic treatment in acute renal insufficiency in obstetrics and gynecology]. | 1969 | Klin Med (Mosk) | pmid:5406822 |
Baer PN et al. | Studies on experimental calculus fomration in the rat XIII. Effect of strain, antibiotics and foster feeding. | 1969 | J. Periodontol. | pmid:5251209 |
Waksman SA | Successes and failures in the search for antibiotics. | 1969 | Adv. Appl. Microbiol. | pmid:4195044 |
Descrozailles C et al. | [A case of facial-ophthalmic thrombophlebitis during dental treatment]. | 1969 | Rev Stomatol Chir Maxillofac | pmid:5254109 |
Lobene RR et al. | Effect of erythromycin on dental plaque and plaque forming microorganisms of man. | 1969 | J. Periodontol. | pmid:5255346 |
Goldman M and Pearson AH | Postdébridement bacterial flora and antibiotic sensitivity. | 1969 | Oral Surg. Oral Med. Oral Pathol. | pmid:5260664 |
Weissenborn K | [Antibacterial effect of gentamicin in the scope of routine antibiogramms]. | 1969 | Arzneimittelforschung | pmid:4981208 |
Amies CR | Sensitivity of Neisseria gonorrhoeae to penicillin and other antibiotics. Studies carried out in Toronto during the period 1961 to 1968. | 1969 | Br J Vener Dis | pmid:4981351 |
Reyn A and Bentzon MW | Relationships between the sensitivities in vitro of Neisseria gonorrhoeae to spiramycin, penicillin, streptomycin, tetracycline, and erythromycin. | 1969 | Br J Vener Dis | pmid:4981352 |
Arescaldino I | [Differential sensitivity to erythromycin of sporogenesis and crystallogenesis in Bacillus thuringiensis]. | 1969 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:4981440 |
Delaire J | [Use of erythromycin ethyl succinate tablets for chewing, their value in dentistry]. | 1969 | Chir Dent Fr | pmid:4981637 |
Myall RW and Gregory HS | Current trends in the prevention of bacterial endocarditis in susceptible patients receiving dental care. | 1969 | Oral Surg. Oral Med. Oral Pathol. | pmid:4982061 |
Muschel LH et al. | Sensitivity of Pseudomonas aeruginosa to normal serum and to polymyxin. | 1969 | J. Bacteriol. | pmid:4306538 |
Elston HR et al. | Listeria monocytogenes endocarditis: a clinical and bacteriological report. | 1969 | Arch. Intern. Med. | pmid:4982382 |
Stone NH et al. | Empirical selection of antibiotics for hand infections. | 1969 | J Bone Joint Surg Am | pmid:4307419 |
Tereshin IM | [Mechanism of action of mitomycin C on genetic transformation of hemolytic Streptococci]. | 1969 | Antibiotiki | pmid:4982962 |
Loire R et al. | [Present developmental aspect of infectious endocarditis. According to hospital statistics of 103 consecutive cases collected in the last 12 years]. | 1969 | Sem Hop | pmid:4308671 |
Serebrennikova II | [Correlation between sensitivity of diphtheria bacteria to antibiotics and the presence of fungi of the Candida order]. | 1969 | Antibiotiki | pmid:4982964 |
Nishida M et al. | Studies on microbial degradation of carbenicillin. | 1969 | J. Antibiot. | pmid:4310240 |
Stephens VC et al. | A study of the behavior of propionyl erythromycin in blood by a new chromatographic method. | 1969 | J. Antibiot. | pmid:4983351 |
McCracken GH et al. | Antimicrobial therapy in theoy and practice. I. Clinical pharmacology. | 1969 | J. Pediatr. | pmid:4310466 |
Saslaw S et al. | Therapy of staphylococcal infections in monkeys. IV. Further comparison of triacetyloleandomycin and erythromycins. | 1969 | Appl Microbiol | pmid:4984259 |
Blumberg N | Penicillin-resistant gonorrhea. | 1969 | J. Urol. | pmid:5189316 |
Raska B and Hradcová L | [The significance of the acid-base balance in pyelonephritis in childhood before and after operative intervention]. | 1969 | Monatsschr Kinderheilkd | pmid:4914869 |
Veselov AIa | [On the correlation between sensitivity to antibiotics and bacteriphages in staphylococci]. | 1969 | Antibiotiki | pmid:4238756 |
Braun P | Hepatotoxicity of erythromycin. | 1969 | J. Infect. Dis. | pmid:4888905 |
Veselov AIa | [Dynamics of sensitivity to antibiotics of pathogenic staphylococci, isolated from different sources]. | 1969 | Antibiotiki | pmid:4889838 |
Kalabukhova NF and Ermol'eva ZV | [Comparative study of sensitivity of enteropathogenic coli bacteria and proteus to ampicillin and its combination with other antibiotics]. | 1969 | Antibiotiki | pmid:4889844 |
Demarco PV | Pyridine solvent shifts in the NMR analysis of etythromycin aglycones. | 1969 | Tetrahedron Lett. | pmid:5779748 |
Ekisenina NI et al. | [Use of prodigiozan in chronic diseases of intestine]. | 1969 | Antibiotiki | pmid:4889845 |
Perun TJ and Egan RS | The conformation of erythromycin aglycones. | 1969 | Tetrahedron Lett. | pmid:5779749 |
Cerná J et al. | The effect of antibiotics on the coded binding of peptidyl-tRNA to the ribosome and on the transfer of the peptidyl residue to puromycin. | 1969 | Eur. J. Biochem. | pmid:4891613 |
Jones PH et al. | Insoluble erythromycin salts. | 1969 | J Pharm Sci | pmid:5782028 |
Grekova GN | [Sensitivity of Proteus vulgaris, isolated from patients with acute disorders of gastro-intestinal tract, to different antibiotics and furacillin]. | 1969 | Antibiotiki | pmid:4891714 |
Montes LF et al. | Erythrasma and diabetes mellitus. | 1969 | Arch Dermatol | pmid:5783076 |
Brovtsyna AV | [Study of sensitivity of antibiotics of microbes from the genus Shigella]. | 1969 | Antibiotiki | pmid:4891715 |
Weisblum B and Demohn V | Erythromycin-inducible resistance in Staphylococcus aureus: survey of antibiotic classes involved. | 1969 | J. Bacteriol. | pmid:5784204 |
Kirschmann C and Davis BD | Phenotypic suppression in Escherichia coli by chloramphenicol and other reversible inhibitors of the ribosome. | 1969 | J. Bacteriol. | pmid:4891806 |
Raveau MJ | [Use in pediatrics of a new form of erythromycin: erythromycin ethyl succinate]. | 1969 | J Med Lyon | pmid:5784250 |
Tanaka N et al. | Mechanism of inhibition of protein synthesis by fusidic acid and related steroidal antibiotics. | 1969 | J. Biochem. | pmid:4892538 |
DeSalva SJ et al. | Lethal effects of antibiotics in hamsters. | 1969 | Toxicol. Appl. Pharmacol. | pmid:5787519 |
Evans RJ and Franklin AJ | Haemophilus influenzae type B septicemia. | 1969 | Br Med J | pmid:5305534 |
Saito T et al. | Drug resistance of staphylococci. Foation of erythromycin-ribosome complex. Decrease in the formation of erythromycin-ribosome complex in erythromycin resistant strains of Staphylococcus aureus. | 1969 | Jpn. J. Microbiol. | pmid:5305691 |
Watson KC | Laboratory evaluation of erythromycin in a general hospital. | 1969 | S. Afr. Med. J. | pmid:4389248 |
Lapinski EM and Flakas ED | Effects of antibiotics on induction, viability, and reversion potential of L-forms of Haemophilus influenzae. | 1969 | J. Bacteriol. | pmid:5305776 |
Osono T et al. | [Studies on josamycin. 3. (1) Bacteriological studies. (2) Protective effect against infections due to pathogenic bacteria. (3) Absorption, excretion, distribution in organs and in vivo activities]. | 1969 | Jpn J Antibiot | pmid:4389777 |
Ravin AW et al. | Genetic and biochemical studies of suppression of ribosomal resistance to streptomycin and erythromycin in Pneumococcus. | 1969 | Genetics | pmid:4389851 |
dos Santos Morais ML | [Clinico-pathological results using erythromycin stearate in the treatment of intestinal amebiasis]. | 1969 | Hospital (Rio J) | pmid:5306428 |
Waitz JA et al. | Biological activity of megalomicin, a new Micromonospora-produced macrolide antibiotic complex. | 1969 | J. Antibiot. | pmid:4390258 |
de Santana AF | [Ethyl succinate erythromycin and trisulphapyridine combination in the treatment of respiratory infections in pediatric outpatients]. | 1969 | Hospital (Rio J) | pmid:5306432 |
Gabor M and Hotchkiss RD | Differences in rate of phenotypic expression in separated strands of pneumococcal transforming DNA and evidence for change of reading direction. | 1969 | Genetics | pmid:4390535 |
Bestani WJ | [An erythromycin-trisulfapyrimidine combination in genitourinary infections]. | 1969 | Hospital (Rio J) | pmid:5306490 |
Kuriaki K et al. | [New antibiotics, Josamycin. VI. Study on absorption and distribution of Josamycin]. | 1969 | Jpn J Antibiot | pmid:5306999 |
Wense G | [Postoperative enterocolitis]. | 1969 | Zentralbl Chir | pmid:4391871 |
Zadvorniak PV and BronshteÄn RE | [Microflora of lungs in pneumonias of infants and its sensitivity to antibiotics]. | 1969 | Antibiotiki | pmid:4391893 |
de Oliveira CA | [Therapeutic experience in the use of erythromycin stearate in chronic intestinal amebiasis]. | 1969 | Hospital (Rio J) | pmid:5307522 |
Miniti A et al. | [Comparative study of antibiotic activity in bacterial infections in hospital practice]. | 1969 | Hospital (Rio J) | pmid:5307637 |
Kalabukhova NF and Ermol'eva ZV | [Comparative study of the sensitivity of Shigella Sonnei to ampicillin and its combinations with other antibiotics]. | 1969 | Antibiotiki | pmid:4935891 |
Lebioda J et al. | [TPI and FTA tests in the evaluation of effectiveness of the oral treatment of early symptomatic syphilis with detreomycin, erythromycin and oxytetracycline with consideration of the clinical picture]. | 1969 | Przegl Dermatol | pmid:4906972 |
Jakubowski A | [Present state of experimental studies on the effect of antibiotics other than penicillin on Treponema pallidum in vitro]. | 1969 | Przegl Dermatol | pmid:4906975 |