erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hematuria D006417 13 associated lipids
Hemoglobin SC Disease D006450 2 associated lipids
Hemolysis D006461 131 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Herpes Genitalis D006558 2 associated lipids
Herpes Zoster Ophthalmicus D006563 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Hyperhidrosis D006945 2 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hypersplenism D006971 3 associated lipids
Hypertension D006973 115 associated lipids
Hypotension D007022 41 associated lipids
Hypothermia D007035 19 associated lipids
Hypoventilation D007040 2 associated lipids
Impetigo D007169 3 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Inflammation D007249 119 associated lipids
Intestinal Atresia D007409 3 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Intraoperative Complications D007431 5 associated lipids
Ischemia D007511 18 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Laryngitis D007827 5 associated lipids
Legionellosis D007876 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leishmaniasis D007896 19 associated lipids
Leprosy D007918 8 associated lipids
Leukemia D007938 74 associated lipids
Leukemia P388 D007941 43 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lipidoses D008064 7 associated lipids
Listeriosis D008088 12 associated lipids
Liver Abscess D008100 6 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Reinert RR et al. In vitro activities of the new ketolide antibiotics HMR 3004 and HMR 3647 against Streptococcus pneumoniae in Germany. 1998 Antimicrob. Agents Chemother. pmid:9624505
Roblin PM and Hammerschlag MR In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae. 1998 Antimicrob. Agents Chemother. pmid:9624507
Souli M et al. In vitro activity of BAY 12-8039, a new fluoroquinolone, against species representative of respiratory tract pathogens. 1998 Int. J. Antimicrob. Agents pmid:9624540
Wirsing von König CH et al. Factors influencing the spread of pertussis in households. 1998 Eur. J. Pediatr. pmid:9625336
Wandel C et al. Effect of CYP3A inhibition on vesnarinone metabolism in humans. 1998 Clin. Pharmacol. Ther. pmid:9630823
Stassi DL et al. Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9636144
Novaes AB et al. Immediate implants placed into infected sites: a histomorphometric study in dogs. 1998 May-Jun Int J Oral Maxillofac Implants pmid:9638015
Havlik J and Holý M [Erythromycin stearate Spofa--coated tablets for pediatric practice]. 1976 Cesk Pediatr pmid:963828
Shimatani T Involvement of cholinergic motor neurons in pharmacological regulation of gastrointestinal motility by glucagon in conscious dogs. 1997 Aug-Oct J Smooth Muscle Res pmid:9639019
Oyarzún E et al. Antibiotic treatment in preterm labor and intact membranes: a randomized, double-blinded, placebo-controlled trial. 1998 May-Jun J Matern Fetal Med pmid:9642605
Jeffreys AJ and Craig IW Analysis of proteins synthesized in mitochondria of cultured mammalian cells. An assessment of current approaches and problems in interpretation. 1976 Eur. J. Biochem. pmid:964267
Kobashi Y et al. [A case of Listeria monocytogenes sepsis in an elderly who survived]. 1998 Kansenshogaku Zasshi pmid:9642946
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Shryock TR et al. Antimicrobial susceptibility of Moraxella bovis. 1998 Vet. Microbiol. pmid:9646479
Pasco J What has the patient been taking? 1998 Aust Fam Physician pmid:9648320
Gharaibeh MN et al. Effect of multiple doses of rifampin on the [14C N-methyl] erythromycin breath test in healthy male volunteers. 1998 J Clin Pharmacol pmid:9650537
Suzuki Y et al. [Antimicrobial activities of clindamycin against clinical isolated Streptococcus pneumoniae]. 1997 Jpn J Antibiot pmid:9651606
Wehbeh HA et al. Single-dose azithromycin for Chlamydia in pregnant women. 1998 J Reprod Med pmid:9653697
O'Halloran HS et al. Leber's neuroretinitis in a patient with serologic evidence of Bartonella elizabethae. 1998 Retina (Philadelphia, Pa.) pmid:9654422
Orden B et al. Erythromycin resistance of Streptococcus pyogenes in Madrid. 1998 Pediatr. Infect. Dis. J. pmid:9655536
Kuyucu N et al. Comparison of oral erythromycin, local administration of streptomycin and placebo therapy for nonsuppurative Bacillus Calmette-Guérin lymphadenitis. 1998 Pediatr. Infect. Dis. J. pmid:9655549
Rangel-Lugo M et al. Prevention of antibiotic residues in veal calves fed colostrum. 1998 J. Am. Vet. Med. Assoc. pmid:9656021
[Streptococcus pyogenes and resistance to macrolides: experience at Monza]. 1998 Jan-Feb Minerva Pediatr. pmid:9658791
Azuma A et al. Preventive effect of erythromycin on experimental bleomycin-induced acute lung injury in rats. 1998 Thorax pmid:9659353
Schultz MJ et al. Erythromycin inhibits tumor necrosis factor alpha and interleukin 6 production induced by heat-killed Streptococcus pneumoniae in whole blood. 1998 Antimicrob. Agents Chemother. pmid:9660992
Kadota J et al. Inhibitory effect of erythromycin on superoxide anion production by human neutrophils primed with granulocyte-colony stimulating factor. 1998 Antimicrob. Agents Chemother. pmid:9661038
D'Souza P et al. A comparative study of therapeutic response of patients with clinical chancroid to ciprofloxacin, erythromycin, and cotrimoxazole. 1998 Sex Transm Dis pmid:9662762
Gamaleia NB and Levashev VS [Biological properties and mechanisms of development of bacteria resistant to fusidin, erythromycin and chloramphenicol]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:96638
Verhagen MA et al. Effects of a new motilide, ABT-229, on gastric emptying and postprandial antroduodenal motility in healthy volunteers. 1997 Aliment. Pharmacol. Ther. pmid:9663833
Griffin RG Dipolar recoupling in MAS spectra of biological solids. 1998 Nat. Struct. Biol. pmid:9665180
Yagi Y et al. Characterization of a small plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain of Streptococcus sanguis isolated from dental plaque. 1978 Antimicrob. Agents Chemother. pmid:96738
As incidence increases CDC recommends 1976 treatment schedule for syphilis. 1976 Pa Med pmid:967481
Rathgeber J and Burchardi H [Use of the antibiotic erythromycin in intestinal motility disorders]. 1998 Anaesthesist pmid:9676314
Hayakawa H et al. Diffuse panbronchiolitis and rheumatoid arthritis-associated bronchiolar disease: similarities and differences. 1998 Intern. Med. pmid:9678682
Enomoto F et al. [Evaluation of methods of macrolide antibiotic administration in experimental otitis media of rats]. 1997 Jpn J Antibiot pmid:9678980
Ikeda K et al. [Effect of macrolide antibiotics on ion transport of nasal mucosal epithelium]. 1997 Jpn J Antibiot pmid:9678982
Wessel F [Peri-anesthesia allergies to antibiotics]. 1998 Allerg Immunol (Paris) pmid:9684043
Stassi D et al. A genetically engineered strain of Saccharopolyspora erythraea that produces 6,12-dideoxyerythromycin A as the major fermentation product. 1998 Appl. Microbiol. Biotechnol. pmid:9684306
Tripathi S et al. Ketolide resistance conferred by short peptides. 1998 J. Biol. Chem. pmid:9685347
Bowman ED et al. Impact of erythromycin on respiratory colonization of Ureaplasma urealyticum and the development of chronic lung disease in extremely low birth weight infants. 1998 Pediatr. Infect. Dis. J. pmid:9686728
Hamilton-Miller JM and Shah S Comparative in-vitro activity of ketolide HMR 3647 and four macrolides against gram-positive cocci of known erythromycin susceptibility status. 1998 J. Antimicrob. Chemother. pmid:9687104
Gaudreau C and Gilbert H Antimicrobial resistance of clinical strains of Campylobacter jejuni subsp. jejuni isolated from 1985 to 1997 in Quebec, Canada. 1998 Antimicrob. Agents Chemother. pmid:9687415
Petrakis J et al. Enhancement of gastric emptying of solids by erythromycin in patients with Roux-en-Y gastrojejunostomy. 1998 Arch Surg pmid:9687997
Ehrenpreis ED et al. Which form of erythromycin should be used to treat gastroparesis? A pharmacokinetic analysis. 1998 Aliment. Pharmacol. Ther. pmid:9690728
Staunton J Combinatorial biosynthesis of erythromycin and complex polyketides. 1998 Curr Opin Chem Biol pmid:9691072
Kanfer I et al. Analysis of macrolide antibiotics. 1998 J Chromatogr A pmid:9691324
Segura-Corrales J et al. [Cat-scratch disease. Presentation of 2 cases in a family with serologic follow-up and discussion of diagnostic methods]. 1998 Rev Clin Esp pmid:9691742
Weissman KJ et al. Origin of starter units for erythromycin biosynthesis. 1998 Biochemistry pmid:9692995
Milla E et al. Bilateral optic papillitis following mycoplasma pneumoniae pneumonia. 1998 Ophthalmologica pmid:9693295