erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Kawasaki S et al. | [Effects of a steroid and macrolide antibiotic on IL-8 production by neutrophils]. | 1997 | Jpn J Antibiot | pmid:9597446 |
Mineshita M et al. | [Effect of macrolide antibiotics on actin polymerization reactions of neutrophils]. | 1997 | Jpn J Antibiot | pmid:9597447 |
Sato K et al. | [Pyocyanine synthesis by Pseudomonas aeruginosa in chronic airway infection and the effect of erythromycin on its biological activity]. | 1997 | Jpn J Antibiot | pmid:9597453 |
Ohara K et al. | [Effects of pretreatment by erythromycin or rokitamycin on aminoglycoside inactivating enzyme of Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597454 |
Kobayashi O et al. | [Actions of macrolide antibiotics on alginate production by Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597455 |
Kondo K et al. | [Quantitative evaluation of the inhibitory action of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. | 1997 | Jpn J Antibiot | pmid:9597456 |
Kudo S | [Preliminary survey on DPB (diffuse panbronchitis) in Japan and a survey on the status of DPB in China]. | 1997 | Jpn J Antibiot | pmid:9597457 |
Tei A et al. | [Effects and actions of EM (erythromycin), CAM (clarithromycin), and JM (josamycin) on IL-4 and IL-5 production by monocytes]. | 1997 | Jpn J Antibiot | pmid:9597458 |
Hoshina S et al. | [C kinase activation and induction of HL 60 promyelocytic leukemia cell differentiation caused by roxithromycin]. | 1997 | Jpn J Antibiot | pmid:9597464 |
Takada T et al. | [Study of specific mRNA expression by peripheral monocytes of patients with diffuse panbronchitis using cDNA representational difference analysis (RDA)]. | 1997 | Jpn J Antibiot | pmid:9597465 |
Kaseta M et al. | [Study of therapeutic effects of macrolide antibiotics on patients with anti-HTLV-1 antibody positive DPB (diffuse panbronchitis)]. | 1997 | Jpn J Antibiot | pmid:9597466 |
Miyashima S et al. | [Effects of erythromycin on a mouse hypersensitivity pneumonia model]. | 1997 | Jpn J Antibiot | pmid:9597469 |
Nonaka M et al. | [Effects of macrolide antibiotics on fibroblasts]. | 1997 | Jpn J Antibiot | pmid:9597470 |
Hori S et al. | [Effects of macrolide drugs on endogenous glucocorticoids]. | 1997 | Jpn J Antibiot | pmid:9597471 |
Hikariyama T et al. | [Study of suppression of neutrophil functions and prevention of vascular endothelial injury by macrolide antibiotics]. | 1998 | Jpn J Antibiot | pmid:9597473 |
Tamaoki J et al. | [Effects of macrolide antibiotics on iNOS gene expression and NO production by alveolar macrophages]. | 1998 | Jpn J Antibiot | pmid:9597474 |
Takeda H et al. | [Bone absorption suppression by broad spectrum antibiotics]. | 1998 | Jpn J Antibiot | pmid:9597475 |
Kawasaki S et al. | [Effects of a steroid and macrolide antibiotic on adhesion of neutrophils to the airway epithelial cells]. | 1998 | Jpn J Antibiot | pmid:9597483 |
Nakada K et al. | [Therapeutic guideline for diffuse panbronchitis (draft). Subcommittee on Diffuse Lung Diseases, Research Committee on Respiratory Diseases Organized by the Ministry of Health and Welfare]. | 1998 | Jpn J Antibiot | pmid:9597494 |
Shirai R et al. | [Evaluation of the duration of medication with erythromycin for treatment of diffuse panbronchitis--a comparison between interruption of medication and continued administration]. | 1998 | Jpn J Antibiot | pmid:9597496 |