erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sakushima A et al. | Guaiacylglycerol-7'-O-methyl 8'-vanillic acid ether and related compounds from Boreava orientalis. | Phytochem Anal | pmid:12597255 | |
Thomaidou E et al. | Perioperative Use of Erythromycin Reduces Cognitive Decline After Coronary Artery Bypass Grafting Surgery: A Pilot Study. | Clin Neuropharmacol | pmid:28816833 | |
Ghoreishi SM et al. | Effect of orally administered cisapride, bethanechol, and erythromycin on the apparent efficiency of colostral IgG absorption in neonatal Holstein-Friesian calves. | J. Vet. Intern. Med. | pmid:25641234 | |
pmid:5110814 | ||||
Yokohori N et al. | Effectiveness of Combined Therapy with Pirfenidone and Erythromycin for Unclassifiable Interstitial Pneumonia Induced by HTLV-1-associated Bronchioloalveolar Disorder (HABA). | Intern. Med. | pmid:28050003 | |
Bottega A et al. | Evaluation of constitutive and inducible resistance to clindamycin in clinical samples of Staphylococcus aureus from a tertiary hospital. | Rev. Soc. Bras. Med. Trop. | pmid:25467260 | |
pmid:16888699 | ||||
pmid:17760348 | ||||
Zhou W et al. | Erythromycin-resistant genes in group A β-haemolytic Streptococci in Chengdu, Southwestern China. | Indian J Med Microbiol | pmid:25008823 | |
Abraham T and Sistla S | Trends in antimicrobial resistance patterns of Group A streptococci, molecular basis and implications. | Indian J Med Microbiol | pmid:30084408 | |
Cai C et al. | Effects of erythromycin on γ-glutamyl cysteine synthetase and interleukin-1β in hyperoxia-exposed lung tissue of premature newborn rats. | J Pediatr (Rio J) | pmid:24878007 | |
pmid: | ||||
Enyuan Q et al. | Erythromycin combined with corticosteroid reduced inflammation and modified trauma-induced tracheal stenosis in a rabbit model. | Ther Adv Respir Dis | pmid:29781361 | |
Cao T et al. | Anti-pruritic efficacies of doxycycline and erythromycin in the treatment of acne vulgaris: A randomized single-blinded pilot study. | Indian J Dermatol Venereol Leprol | pmid:29770785 | |
Pranteda G et al. | Pitted keratolysis, erythromycin, and hyperhidrosis. | Dermatol Ther | pmid:24703267 | |
Wang X et al. | Phenotypic and molecular characterization of Streptococcus agalactiae colonized in Chinese pregnant women: predominance of ST19/III and ST17/III. | Res. Microbiol. | pmid:29378338 | |
Yayan J and Rasche K | Growing Antibiotic Resistance in Fatal Cases of Staphylococcal Pneumonia in the Elderly. | Adv. Exp. Med. Biol. | pmid:26747068 | |
Alvarez-Sánchez M et al. | [Bacterial resistance in acne? A meta-analysis of the controversy]. | Cir Cir | pmid:26738649 | |
Mondragón-Navarro M et al. | Potential association between erythromycin and cholestatic hepatitis. | Med Intensiva | pmid:26707838 | |
Thomas J et al. | Residents'corner October 2015. DeRmpath&Clinic: Acute generalised exanthematous pustulosis. | Eur J Dermatol | pmid:26693641 | |
Albayrak A et al. | A case of bacillary angiomatosis developed at a burn site. | Indian J Dermatol Venereol Leprol | pmid:22199082 | |
Gencoglan G et al. | Therapeutic hotline: Treatment of prurigo nodularis and lichen simplex chronicus with gabapentin. | Dermatol Ther | pmid:20415827 | |
Jahansepas A et al. | Occurrence of Enterococcus faecalis and Enterococcus faecium in Various Clinical Infections: Detection of Their Drug Resistance and Virulence Determinants. | Microb. Drug Resist. | pmid:28525287 | |
Silva V et al. | Genetic Characterization of vanA-Enterococcus faecium Isolates from Wild Red-Legged Partridges in Portugal. | Microb. Drug Resist. | pmid:28504889 | |
McCutcheon K and Manga P | An antibiotic recipe for an arrhythmic disaster. | Cardiovasc J Afr | pmid:26592910 | |
Commerford PJ | From the Editor's Desk. | Cardiovasc J Afr | pmid:26592903 | |
Fallahpour N et al. | Overproduction of Erythromycin by Ultraviolet Mutagenesis and Expression of ermE Gene in Saccharopolyspora erythraea. | Assay Drug Dev Technol | pmid:29120674 | |
HAIGHT TH and FINLAND M | The antibacterial action of erythromycin. | 1952 | Proc. Soc. Exp. Biol. Med. | pmid:13047351 |
VANNUCCHI V | [Clinical study of a new antibiotic; erythromycin]. | 1952 | Riv Crit Clin Med | pmid:13056483 |
ERYTHROMYCIN. | 1952 | Br Med J | pmid:12987755 | |
ANDERSON RC et al. | The toxicity and distribution of ilotycin. | 1952 | J Am Pharm Assoc Am Pharm Assoc | pmid:12999613 |
ERYTHROMYCIN, new and promising antibiotic. | 1952 | N. Engl. J. Med. | pmid:14947939 | |
HAIGHT TH and FINLAND M | Laboratory and clinical studies on erythromycin. | 1952 | N. Engl. J. Med. | pmid:14947931 |
ERYTHROMYCIN: another antibiotic. | 1952 | Lancet | pmid:14939901 | |
VELEZ MORAN C | [Experience with erythromycin in the Hospital de Aislamiento de Guayaquil]. | 1953 | Rev Ecuat Hig Med Trop | pmid:13237604 |
KIRBY WM et al. | Erythromycin serum concentrations following administration in acid-resistant tablets. | 1953 | Antibiot Chemother (Northfield) | pmid:24542409 |
JONES PN et al. | Use of antibiotics in nonbacterial respiratory infections. | 1953 | J Am Med Assoc | pmid:13084382 |
KIRSHBAUM A et al. | A cupplate method for the determination of erythromycin concentrations in serum and other body fluids. | 1953 | Antibiot Chemother (Northfield) | pmid:24542421 |
ROMANSKY MJ | Current trends in antibiotic therapy. | 1953 | Med Bull US Army Eur | pmid:13085979 |
CLARK RK | The chemistry of erythromycin. I. Acid degradation products. | 1953 | Antibiot Chemother (Northfield) | pmid:24542535 |
FABRE J | [A new antibiotic: erythromycin; its therapeutic effect in 60 cases of various diseases]. | 1953 | Praxis | pmid:13088584 |
MAPLE FM et al. | Serum concentrations of erythromycin following intravenous administration. | 1953 | Antibiot Chemother (Northfield) | pmid:24542586 |
BUNN PA and COOK E | Treatment of pneumococcal pneumonia with erythromycin and carbomycin (magnamycin). | 1953 | AMA Arch Intern Med | pmid:13091455 |
LEE CC et al. | Tissue distribution of erythromycin in rats. | 1953 | Antibiot Chemother (Northfield) | pmid:24542649 |
KIRBY WM et al. | Treatment of staphylococcic infections with erythromycin. | 1953 | AMA Arch Intern Med | pmid:13091463 |
SYLVESTER JC and JOSSELYN LE | Absorption of erythromycin. II. Erythromycin stearate. | 1953 | Antibiot Chemother (Northfield) | pmid:24542651 |
BACON AE | Erythromycin in the treatment of pneumococcal pneumonia. | 1953 | Del Med J | pmid:13094978 |
GRIGSBY ME et al. | Some laboratory and clinical experiences with erythromycin. | 1953 | Antibiot Chemother (Northfield) | pmid:24542704 |
RUIZ SANCHEZ F et al. | [Erythromycin in the treatment of diarrheas due to Micrococcus pyogenes]. | 1953 | Medicina (Mex) | pmid:13098728 |
VANNUCCHI V | [Ilotycin sulfa: association of ilotycin with a trisulfonamide]. | 1953 | Riv Crit Clin Med | pmid:14358369 |