erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Vergis EN et al. Azithromycin vs cefuroxime plus erythromycin for empirical treatment of community-acquired pneumonia in hospitalized patients: a prospective, randomized, multicenter trial. 2000 Arch. Intern. Med. pmid:10809032
Rachek LI et al. Transformation of Rickettsia prowazekii to erythromycin resistance encoded by the Escherichia coli ereB gene. 2000 J. Bacteriol. pmid:10809714
Raimundo BC and Heathcock CH Synthesis of a model for C7-C13 of lankamycin. 2000 Org. Lett. pmid:10814237
Bingen E et al. Resistance to macrolides in Streptococcus pyogenes in France in pediatric patients. 2000 Antimicrob. Agents Chemother. pmid:10817692
Capobianco JO et al. Studies of the novel ketolide ABT-773: transport, binding to ribosomes, and inhibition of protein synthesis in Streptococcus pneumoniae. 2000 Antimicrob. Agents Chemother. pmid:10817709
Terashi K et al. Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells. 2000 Antimicrob. Agents Chemother. pmid:10817732
Munckhof WJ et al. Postantibiotic suppression of growth of erythromycin A-susceptible and -resistant gram-positive bacteria by the ketolides telithromycin (HMR 3647) and HMR 3004. 2000 Antimicrob. Agents Chemother. pmid:10817748
Ueno N et al. Erythromycin improves glycaemic control in patients with Type II diabetes mellitus. 2000 Diabetologia pmid:10819233
Lee B Progressive respiratory distress in an infant treated for presumed pertussis. 2000 Pediatr. Infect. Dis. J. pmid:10819348
Dubois J and St-Pierre C Comparative in vitro activity and post-antibiotic effect of gemifloxacin against Legionella spp. 2000 J. Antimicrob. Chemother. pmid:10824031
Gururaj VJ et al. Triacetyloleandomycin in streptococcal throat infections. A reappraisal of an older antibiotic. 1976 Clin Pediatr (Phila) pmid:1082408
Watkins PB Erythromycin breath test. 2000 Clin. Pharmacol. Ther. pmid:10824637
Govaerts C et al. Investigation of unknown related substances in commercial erythromycin samples with liquid chromatography/mass spectrometry. 2000 Rapid Commun. Mass Spectrom. pmid:10825252
Goldman RC and Tipper DJ Morphology and patterns of protein synthesis during sporulation of Bacillus subtilis Eryr spo(Ts) mutants. 1979 J. Bacteriol. pmid:108263
Zhou J et al. Separation and determination of the macrolide antibiotics (erythromycin, spiramycin and oleandomycin) by capillary electrophoresis coupled with fast reductive voltammetric detection. 2000 Electrophoresis pmid:10826680
Holm M and Tärnvik A Hospitalization due to Pasteurella multocida-infected animal bite wounds: correlation with inadequate primary antibiotic medication. 2000 Scand. J. Infect. Dis. pmid:10826905
Ishioka S et al. An autopsy case of diffuse panbronchiolitis associated with lung cancer. 2000 Intern. Med. pmid:10830183
Usiskin SI et al. Retreatment with clozapine after erythromycin-induced neutropenia. 2000 Am J Psychiatry pmid:10831491
Aarestrup FM et al. Antimicrobial susceptibility and presence of resistance genes in staphylococci from poultry. 2000 Vet. Microbiol. pmid:10831857
Miyashita N et al. In vitro susceptibility of 7.5-kb common plasmid-free Chlamydia trachomatis strains. 2000 Microbiol. Immunol. pmid:10832970
Privitera G et al. Transfer of multiple antibiotic resistance between subspecies of Bacteroides fragilis. 1979 J. Infect. Dis. pmid:108340
Wood KE et al. Phlegmasia cerulea dolens with compartment syndrome: a complication of femoral vein catheterization. 2000 Crit. Care Med. pmid:10834724
Jasir A et al. High rate of tetracycline resistance in Streptococcus pyogenes in Iran: an epidemiological study. 2000 J. Clin. Microbiol. pmid:10834960
Cosgrove DM et al. The management of Hemophilus influenzae, Type B, pericarditis. 1976 Ann. Thorac. Surg. pmid:1083717
Xia M et al. Gonorrhea among men who have sex with men: outbreak caused by a single genotype of erythromycin-resistant Neisseria gonorrhoeae with a single-base pair deletion in the mtrR promoter region. 2000 J. Infect. Dis. pmid:10837198
Schmitz FJ et al. Prevalence of macrolide-resistance genes in Staphylococcus aureus and Enterococcus faecium isolates from 24 European university hospitals. 2000 J. Antimicrob. Chemother. pmid:10837446
Jackson LA et al. Past use of erythromycin, tetracycline, or doxycycline is not associated with risk of first myocardial infarction. 2000 J. Infect. Dis. pmid:10839759
Takahashi Y et al. Accurate mass determination by multiple sprayers nano-electrospray mass spectrometry on a magnetic sector instrument. 2000 Rapid Commun. Mass Spectrom. pmid:10844730
Matsui S et al. [Rheumatoid arthritis-associated bronchiolitis successfully treated with erythromycin]. 2000 Nihon Kokyuki Gakkai Zasshi pmid:10846401
Heikkinen T et al. The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin. 2000 BJOG pmid:10847234
Thami GP and Kanwar AJ Red facial pseudochromhidrosis. 2000 Br. J. Dermatol. pmid:10848751
Meisels HI and Peyman GA Intravitreal erythromycin in the treatment of induced staphylococcal endophthalmitis. 1976 Ann Ophthalmol pmid:1085597
Ohmori M et al. Effect of erythromycin on ischemia-reperfusion injury of liver in rats. 2000 Transplant. Proc. pmid:10856595
Alonso A et al. Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance. 2000 Antimicrob. Agents Chemother. pmid:10858330
Plouffe J et al. Clinical efficacy of intravenous followed by oral azithromycin monotherapy in hospitalized patients with community-acquired pneumonia. The Azithromycin Intravenous Clinical Trials Group. 2000 Antimicrob. Agents Chemother. pmid:10858333
Betriu C et al. Comparative in vitro activities of linezolid, quinupristin-dalfopristin, moxifloxacin, and trovafloxacin against erythromycin-susceptible and -resistant streptococci. 2000 Antimicrob. Agents Chemother. pmid:10858339
Davies TA et al. Antipneumococcal activity of ABT-773 compared to those of 10 other agents. 2000 Antimicrob. Agents Chemother. pmid:10858350
Cull SG et al. Room-temperature ionic liquids as replacements for organic solvents in multiphase bioprocess operations. 2000 Biotechnol. Bioeng. pmid:10861402
Stephenson GA Structure determination from conventional powder diffraction data: application to hydrates, hydrochloride salts, and metastable polymorphs. 2000 J Pharm Sci pmid:10861598
Davies JL et al. Studies on the interaction of fermentation and microfiltration operations: erythromycin recovery from Saccharopolyspora erythraea fermentation broths. 2000 Biotechnol. Bioeng. pmid:10862681
Jones RN et al. In vitro activity of selected cephalosporins and erythromycin against staphylococci and pneumococci isolated at 38 North American medical centers participating in the SENTRY Antimicrobial Surveillance Program, 1997-1998. 2000 Diagn. Microbiol. Infect. Dis. pmid:10863103
Wilkinson D et al. Trial-of-antibiotic algorithm for the diagnosis of tuberculosis in a district hospital in a developing country with high HIV prevalence. 2000 Int. J. Tuberc. Lung Dis. pmid:10864181
Stenmark HG et al. Biomimetic synthesis of macrolide/ketolide metabolites through a selective N-demethylation reaction. 2000 J. Org. Chem. pmid:10864780
Quintieri L et al. In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A. 2000 Cancer Res. pmid:10866316
Fujita K et al. Effects of macrolides on interleukin-8 secretion from human nasal epithelial cells. 2000 Eur Arch Otorhinolaryngol pmid:10867834
Pandey RC and Rinehart KL Polyene antibiotics. VII. Carbon-13 nuclear magnetic resonance evidence for cyclic hemiketals in the polyene antibiotics amphotericin B, nystatin A1, tetrin A, tetrin B, lucensomycin, and pimaricin1,2. 1976 J. Antibiot. pmid:1086913
Cowles VE et al. Effect of novel motilide ABT-229 versus erythromycin and cisapride on gastric emptying in dogs. 2000 J. Pharmacol. Exp. Ther. pmid:10869416
Kanamitsu S et al. Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4. 2000 Pharm. Res. pmid:10870985
Lazarczyk DA and Duffy MC Erythromycin-induced primary biliary cirrhosis. 2000 Dig. Dis. Sci. pmid:10877225
Yan JJ et al. Prevalence of polyclonal mefA-containing isolates among erythromycin-resistant group A streptococci in Southern Taiwan. 2000 J. Clin. Microbiol. pmid:10878028