| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Bone Resorption | D001862 | 7 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Maganti K et al. | Oral erythromycin and symptomatic relief of gastroparesis: a systematic review. | 2003 | Am. J. Gastroenterol. | pmid:12591038 |
| Chang AD et al. | Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). | 1996 | Am. J. Gastroenterol. | pmid:8855753 |
| DITTLER EL | Upper abdominal pain and intrahepatic cholestasis as manifestations of sensitivity to ilosone. | 1962 | Am. J. Gastroenterol. | pmid:14028076 |
| Hakkal HG | Pseudomembraneous colitis associated with antibiotics. | 1976 | Am. J. Gastroenterol. | pmid:1274934 |
| Rayner CK et al. | The stimulation of antral motility by erythromycin is attenuated by hyperglycemia. | 2000 | Am. J. Gastroenterol. | pmid:11007223 |
| Resnick J et al. | Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. | 1997 | Am. J. Gastroenterol. | pmid:9177505 |
| Keshavarzian A and Isaac RM | Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. | 1993 | Am. J. Gastroenterol. | pmid:8424419 |
| Mantides A et al. | The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. | 1993 | Am. J. Gastroenterol. | pmid:8424420 |
| Richards RD et al. | The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. | 1993 | Am. J. Gastroenterol. | pmid:8424421 |
| Bonacini M et al. | Effect of intravenous erythromycin on postoperative ileus. | 1993 | Am. J. Gastroenterol. | pmid:8424422 |
| Weber FH et al. | Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. | 1993 | Am. J. Gastroenterol. | pmid:8470625 |
| McNulty CA | The treatment of Campylobacter-associated gastritis. | 1987 | Am. J. Gastroenterol. | pmid:3493685 |
| Koutsoumbi P et al. | The effect of erythromycin on human esophageal motility is mediated by serotonin receptors. | 2000 | Am. J. Gastroenterol. | pmid:11151866 |
| Portincasa P et al. | The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study. | 2000 | Am. J. Gastroenterol. | pmid:11151875 |
| Carmagnola S et al. | Mechanoreceptors of the proximal stomach and perception of gastric distension. | 2005 | Am. J. Gastroenterol. | pmid:16086705 |
| Ecker JA et al. | Pseudomembraneous enterocolitis--an unwelcome gastrointestinal complication of antibiotic therapy. | 1970 | Am. J. Gastroenterol. | pmid:4319211 |
| Kalkay MN et al. | Campylobacter-induced toxic megacolon. | 1983 | Am. J. Gastroenterol. | pmid:6613968 |
| Laine L and Jensen DM | Management of patients with ulcer bleeding. | 2012 | Am. J. Gastroenterol. | pmid:22310222 |
| Tanaka M et al. | Agranulocytosis induced by macrolide antibiotics. | 1995 | Am. J. Hematol. | pmid:7847332 |
| Singer DR et al. | Drug hypersensitivity causing granulomatous interstitial nephritis. | 1988 | Am. J. Kidney Dis. | pmid:3354573 |
| MartÃnez-Maldonado M | Postinfectious glomerulonephritis. | 2000 | Am. J. Kidney Dis. | pmid:10636819 |
| Mery JP and Kanfer A | Alterations in pharmacokinetics and ototoxicity of erythromycin in renal failure. | 1984 | Am. J. Kidney Dis. | pmid:6741942 |
| Silang R et al. | Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying. | 2001 | Am. J. Kidney Dis. | pmid:11157368 |
| Ross EA and Koo LC | Improved nutrition after the detection and treatment of occult gastroparesis in nondiabetic dialysis patients. | 1998 | Am. J. Kidney Dis. | pmid:9428453 |
| Ragosta M et al. | Potentially fatal interaction between erythromycin and disopyramide. | 1989 | Am. J. Med. | pmid:2467560 |
| Gumaste VV | Erythromycin-induced pancreatitis. | 1989 | Am. J. Med. | pmid:2729328 |
| Curtis LH et al. | Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. | 2003 | Am. J. Med. | pmid:12586234 |
| Nattel S et al. | Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism. | 1990 | Am. J. Med. | pmid:2382671 |
| Klein JO | Emerging perspectives in management and prevention of infections of the respiratory tract in infants and children. | 1985 | Am. J. Med. | pmid:4014286 |
| Rudin JE et al. | Failure of erythromycin in treatment of Legionella micdadei pneumonia. | 1984 | Am. J. Med. | pmid:6607673 |
| Diehl AM et al. | Cholestatic hepatitis from erythromycin ethylsuccinate. Report of two cases. | 1984 | Am. J. Med. | pmid:6609640 |
| Parker RH et al. | Erythromycin-resistant pneumococcal osteomyelitis. | 1970 | Am. J. Med. | pmid:5415405 |
| Sacristán JA and Soto J | Erythromycin ototoxicity: methodology and conclusions. | 1993 | Am. J. Med. | pmid:8430720 |
| Wong KF et al. | Psittacosis-associated hemophagocytic syndrome. | 1991 | Am. J. Med. | pmid:1867249 |
| Tablan OC and Reyes MP | Chronic interstitial pulmonary fibrosis following Mycoplasma pneumoniae pneumonia. | 1985 | Am. J. Med. | pmid:4025379 |
| Vianna NJ and Hinman AR | Rocky Mountain spotted fever on Long Island. Epidemiologic and clinical aspects. | 1971 | Am. J. Med. | pmid:5129543 |
| DAVIS DS and ROMANSKY MJ | Successful treatment of gonococcic endocarditis with erythromycin; review of the literature. | 1956 | Am. J. Med. | pmid:13354638 |
| Augenbraun MH et al. | Chlamydia pneumoniae pneumonia with pleural effusion: diagnosis by culture. | 1991 | Am. J. Med. | pmid:1951390 |
| Swanson DJ et al. | Erythromycin ototoxicity: prospective assessment with serum concentrations and audiograms in a study of patients with pneumonia. | 1992 | Am. J. Med. | pmid:1731511 |
| Moellering RC | Introduction: revolutionary changes in the macrolide and azalide antibiotics. | 1991 | Am. J. Med. | pmid:1656735 |
| Friedland L et al. | Ocular and pericardial involvement in Legionnaires' disease. | 1984 | Am. J. Med. | pmid:6507461 |
| Bolton WK et al. | Ventriculojugular shunt nephritis with Corynebacterium bovis. Successful therapy with antibiotics. | 1975 | Am. J. Med. | pmid:1163549 |
| Quintiliani R and Hymans PJ | The association of bacteremic Haemophilus influenzae pneumonia in adults with typable strains. | 1971 | Am. J. Med. | pmid:5314534 |
| Stocks JM et al. | Ofloxacin in community-acquired lower respiratory infections. A comparison with amoxicillin or erythromycin. | 1989 | Am. J. Med. | pmid:2690620 |
| Dull JS et al. | Successful treatment of gastroparesis with erythromycin in a patient with progressive systemic sclerosis. | 1990 | Am. J. Med. | pmid:2220887 |
| Watanakunakorn C | Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. | 1976 | Am. J. Med. | pmid:1045861 |
| Bowler WA et al. | Gastrointestinal side effects of intravenous erythromycin: incidence and reduction with prolonged infusion time and glycopyrrolate pretreatment. | 1992 | Am. J. Med. | pmid:1546723 |
| Bor DH and Himmelstein DU | Endocarditis prophylaxis for patients with mitral valve prolapse. A quantitative analysis. | 1984 | Am. J. Med. | pmid:6711576 |
| Unertl KE et al. | Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. | 1989 | Am. J. Med. | pmid:2589356 |
| Trimble GX | Acute pancreatitis induced by erythromycin. | 1989 | Am. J. Med. | pmid:2589410 |