erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Granovsky-Grisaru S et al. Effects of erythromycin on contractility of isolated myometrium from pregnant rats. 1998 Am. J. Obstet. Gynecol. pmid:9465824
Bowie WR et al. Efficacy of treatment regimens for lower urogenital Chlamydia trachomatis infection in women. 1982 Am. J. Obstet. Gynecol. pmid:7055176
McGregor JA et al. Cervicovaginal microflora and pregnancy outcome: results of a double-blind, placebo-controlled trial of erythromycin treatment. 1990 Am. J. Obstet. Gynecol. pmid:2240110
Andrews JI et al. Group B streptococci causing neonatal bloodstream infection: antimicrobial susceptibility and serotyping results from SENTRY centers in the Western Hemisphere. 2000 Am. J. Obstet. Gynecol. pmid:11035326
Charles AG et al. Asymptomatic gonorrhea in prenatal patients. 1970 Am. J. Obstet. Gynecol. pmid:5505990
Beckner RR et al. Ototoxicity of erythromycin gluceptate. 1981 Am. J. Obstet. Gynecol. pmid:7211980
Gauthier DW et al. Expectant management of premature rupture of membranes with amniotic fluid cultures positive for Ureaplasma urealyticum alone. 1994 Am. J. Obstet. Gynecol. pmid:8116718
Mercer BM et al. Prenatal screening for group B Streptococcus. I. Impact of antepartum screening on antenatal prophylaxis and intrapartum care. 1995 Am. J. Obstet. Gynecol. pmid:7573254
Campbell WF and Dodson MG Clindamycin therapy for Chlamydia trachomatis in women. 1990 Am. J. Obstet. Gynecol. pmid:2178426
Silverman NS et al. A randomized, prospective trial comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy. 1994 Am. J. Obstet. Gynecol. pmid:8141211
Friberg J Genital mycoplasma infections. 1978 Am. J. Obstet. Gynecol. pmid:362924
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Alger LS and Lovchik JC Comparative efficacy of clindamycin versus erythromycin in eradication of antenatal Chlamydia trachomatis. 1991 Am. J. Obstet. Gynecol. pmid:1872343
Eschenbach DA et al. A randomized placebo-controlled trial of erythromycin for the treatment of Ureaplasma urealyticum to prevent premature delivery. The Vaginal Infections and Prematurity Study Group. 1991 Am. J. Obstet. Gynecol. pmid:2003533
Romero R et al. Antibiotic treatment of preterm labor with intact membranes: a multicenter, randomized, double-blinded, placebo-controlled trial. 1993 Am. J. Obstet. Gynecol. pmid:8238130
Quinn PA et al. Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. 1983 Am. J. Obstet. Gynecol. pmid:6849358
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Croak A et al. Predominance of serotype V and frequency of erythromycin resistance in Streptococcus agalactiae in Ohio. 2003 Am. J. Obstet. Gynecol. pmid:12748459
Hussain N and Herson VC Erythromycin use during pregnancy in relation to pyloric stenosis. 2002 Am. J. Obstet. Gynecol. pmid:12237674
Milwidsky A et al. Direct inhibition of proteases and cervical plasminogen activator by antibiotics. 1992 Am. J. Obstet. Gynecol. pmid:1536241
Johnson RB The role of azalide antibiotics in the treatment of Chlamydia. 1991 Am. J. Obstet. Gynecol. pmid:1645503
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Danielian P Erythromycin, motilin, and meconium. 1992 Am. J. Obstet. Gynecol. pmid:1536263
Goldberg JD and Golbus MS The value of case reports in human teratology. 1986 Am. J. Obstet. Gynecol. pmid:3456709
Keelan JA et al. Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. 2011 Am. J. Obstet. Gynecol. pmid:21481833
Mercer BM et al. The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. 2012 Am. J. Obstet. Gynecol. pmid:22000668
Kundsin RB et al. Ureaplasma urealyticum resistance to erythromycin: confirmed by clinical trial. 1992 Am. J. Obstet. Gynecol. pmid:1615998
Mercer BM et al. Erythromycin therapy in preterm premature rupture of the membranes: a prospective, randomized trial of 220 patients. 1992 Am. J. Obstet. Gynecol. pmid:1550145
McGregor JA et al. Adjunctive erythromycin treatment for idiopathic preterm labor: results of a randomized, double-blinded, placebo-controlled trial. 1986 Am. J. Obstet. Gynecol. pmid:3511709
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Cimolai N Ocular methicillin-resistant Staphylococcus aureus infections in a newborn intensive care cohort. 2006 Am. J. Ophthalmol. pmid:16815280
Lee WR et al. Bacillary angiomatosis of the conjunctiva. 1994 Am. J. Ophthalmol. pmid:8053460
BUTTON RR Treatment of trachoma with erythromycin; a preliminary report of 21 cases. 1955 Am. J. Ophthalmol. pmid:13228536
Okumoto M and Smolin G Pneumococcal infections of the eye. 1974 Am. J. Ophthalmol. pmid:4149786
Maskin SL Infectious scleritis after a diabetic foot ulcer. 1993 Am. J. Ophthalmol. pmid:8430739
Maichuk YF Some aspects of rational trachoma therapy. 1972 Am. J. Ophthalmol. pmid:5075138
HALLETT JW and LEOPOLD IH Clinical trial of erythromycin ophthalmic ointment. 1957 Am. J. Ophthalmol. pmid:13469938
Genvert GI et al. Erythema multiforme after use of topical sulfacetamide. 1985 Am. J. Ophthalmol. pmid:3157322
FURGIUELE FP NEW ANTIBIOTICS: THEIR INTRAOCULAR PENETRATION. II. 1964 Am. J. Ophthalmol. pmid:14204806
Bartley GB and Messenger MM Outcome of tarsoconjunctival flap dehiscence after eyelid reconstruction. 2002 Am. J. Ophthalmol. pmid:12383835
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Steele RJ and Meyer DR Nasolacrimal duct obstruction and acute dacryocystitis associated with infectious mononucleosis (Epstein-Barr virus) 1993 Am. J. Ophthalmol. pmid:8381586
Smith RE et al. Mycobacterium chelonei and orbital granuloma after tear duct probing. 1980 Am. J. Ophthalmol. pmid:7356779
NAIB K et al. Observations on the ocular effects of erythromycin. 1955 Am. J. Ophthalmol. pmid:14350055
Newman PE et al. A cluster of cases of Mycobacterium chelonei keratitis associated with outpatient office procedures. 1984 Am. J. Ophthalmol. pmid:6702973