| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Bone Resorption | D001862 | 7 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Costa A et al. | In vivo characterization of the colonic prokinetic effect of erythromycin in the rabbit. | 1997 | Pharmacology | pmid:9088039 |
| Konishi T and Nakao M | Antibiotic treatment in mice infected with Japanese Borrelia garinii: efficacy of ceftriaxone for eradicating the infection induced by Ixodes persulcatus tick bites. | 1997 | Microbiol. Immunol. | pmid:9087959 |
| Wu JJ et al. | High incidence of erythromycin-resistant streptococci in Taiwan. | 1997 | Antimicrob. Agents Chemother. | pmid:9087502 |
| Traub WH and Leonhard B | Antibiotic susceptibility of alpha- and nonhemolytic streptococci from patients and healthy adults to 24 antimicrobial drugs. | 1997 Mar-Apr | Chemotherapy | pmid:9084921 |
| Qadri SM et al. | In vitro activity of quinupristin/dalfopristin, RP59500, against gram-positive clinical isolates. | 1997 Mar-Apr | Chemotherapy | pmid:9084917 |
| al-Humayyd MS | Pharmacokinetic interactions between erythromycin, clarithromycin, roxithromycin and phenytoin in the rat. | 1997 Mar-Apr | Chemotherapy | pmid:9084915 |
| Walz A et al. | Excellent activity of newer quinolones on Legionella pneumophila in J774 macrophages. | 1997 | Zentralbl. Bakteriol. | pmid:9084116 |
| Hoppe JE | [Whooping cough in pregnant patients and newborn infants]. | 1996 Nov-Dec | Z Geburtshilfe Neonatol | pmid:9081753 |
| Pehl C et al. | Effect of erythromycin on postprandial gastroesophageal reflux in reflux esophagitis. | 1997 | Dis. Esophagus | pmid:9079271 |
| Eisenberg VH et al. | Legionnaire's disease during pregnancy: a case presentation and review of the literature. | 1997 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:9076416 |
| Hueston WJ | Antibiotics: neither cost effective nor 'cough' effective. | 1997 | J Fam Pract | pmid:9071245 |
| Matsumoto K et al. | [Effects of erythromycin on H2O2 generation by neutrophils]. | 1997 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:9071149 |
| Renneberg J et al. | Antimicrobial susceptibility of 278 streptococcal blood isolates to seven antimicrobial agents. | 1997 | J. Antimicrob. Chemother. | pmid:9069532 |
| Chu A et al. | The comparative efficacy of benzoyl peroxide 5%/erythromycin 3% gel and erythromycin 4%/zinc 1.2% solution in the treatment of acne vulgaris. | 1997 | Br. J. Dermatol. | pmid:9068739 |
| Watkins VS et al. | Drug interactions of macrolides: emphasis on dirithromycin. | 1997 | Ann Pharmacother | pmid:9066944 |
| Moutard I et al. | In vitro interaction between dirithromycin or its metabolite, erythromycylamine, and oxidative polymorphonuclear metabolism. | 1997 | J. Antibiot. | pmid:9066766 |
| Furuno T et al. | The role of neutrophil elastase in human pulmonary artery endothelial cell injury. | 1997 | Int. Arch. Allergy Immunol. | pmid:9066513 |
| Matsuoka M et al. | A dyadic plasmid that shows MLS and PMS resistance in Staphylococcus aureus. | 1997 | FEMS Microbiol. Lett. | pmid:9066116 |
| Weiss I et al. | Serotyping and susceptibility to macrolides and other antimicrobial drugs of Streptococcus pyogenes isolated from patients with invasive diseases in southern Israel. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9063669 |
| GarcÃa-de-Lomas J et al. | Antimicrobial susceptibility of Streptococcus pneumoniae isolated from pediatric carriers in Spain. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9063666 |
| Yagiela JA | Prophylactic antibiotics: cardiac and prosthetic considerations. | 1995 | J Calif Dent Assoc | pmid:9063197 |
| Johnsson H and Niklasson PM | Effects of some antibiotics of platelet function in vitro and in vivo. | 1977 | Thromb. Res. | pmid:905975 |
| Petersen K et al. | The effect of erythromycin on resolution of symptoms among adults with pharyngitis not caused by group A streptococcus. | 1997 | J Gen Intern Med | pmid:9051558 |
| Asai T | Erythromycin and motilin as gastrointestinal prokinetic agents. | 1997 | Eur J Anaesthesiol | pmid:9049551 |
| Pieper R et al. | Purification and characterization of bimodular and trimodular derivatives of the erythromycin polyketide synthase. | 1997 | Biochemistry | pmid:9048569 |
| Kim TH et al. | Pseudo-Kaposi's sarcoma associated with acquired arteriovenous fistula. | 1997 | J. Dermatol. | pmid:9046737 |
| Caboche M | Methionine metabolism in BHK cells: the regulation of methionine adenosyltransferase. | 1977 | J. Cell. Physiol. | pmid:903381 |
| Matera MG et al. | Pulmonary concentrations of dirithromycin and erythromycin during acute exacerbation of mild chronic obstructive pulmonary disease. | 1997 | Eur. Respir. J. | pmid:9032500 |
| Baumueller A et al. | Prostatic tissue and secretion concentrations of rosamicin and erythromycin. Experimental studies in the dog. | 1977 | Invest Urol | pmid:903212 |
| Padhi ID et al. | Interaction between tacrolimus and erythromycin. | 1997 | Ther Drug Monit | pmid:9029762 |
| Cupp-Vickery JR and Poulos TL | Structure of cytochrome P450eryF: substrate, inhibitors, and model compounds bound in the active site. | 1997 | Steroids | pmid:9029724 |
| Van Royen P et al. | Dirithromycin versus amoxiclav in the treatment of acute exacerbations of chronic bronchitis. | 1997 Jan-Feb | J. Int. Med. Res. | pmid:9027671 |
| Minami T et al. | Effects of erythromycin in chronic idiopathic intestinal pseudo-obstruction. | 1996 | J. Gastroenterol. | pmid:9027652 |
| Berg-Candolfi M and Candolfi E | Depression of the N-demethylation of erythromycin, azithromycin, clarithromycin and clindamycin in murine Toxoplasma infection. | 1996 | Int. J. Parasitol. | pmid:9024879 |
| Burkhart GA et al. | Temporal decline in filling prescriptions for terfenadine closely in time with those for either ketoconazole or erythromycin. | 1997 | Clin. Pharmacol. Ther. | pmid:9024177 |
| Wolfson C et al. | The Etest for antimicrobial susceptibility testing of Bartonella henselae. | 1996 | J. Antimicrob. Chemother. | pmid:9023643 |
| Tokinaga N et al. | Hallucinations after a therapeutic dose of benzodiazepine hypnotics with co-administration of erythromycin. | 1996 | Psychiatry Clin. Neurosci. | pmid:9014234 |
| Goldberg MJ et al. | Effect of dirithromycin on human CYP3A in vitro and on pharmacokinetics and pharmacodynamics of terfenadine in vivo. | 1996 | J Clin Pharmacol | pmid:9013373 |
| Kupferman A and Leibowitz HM | Topical antibiotic therapy of staphylococcal keratitis. | 1977 | Arch. Ophthalmol. | pmid:901273 |
| Cornaglia G et al. | Rapid increase of resistance to erythromycin and clindamycin in Streptococcus pyogenes in Italy, 1993-1995. The Italian Surveillance Group for Antimicrobial Resistance. | 1996 Oct-Dec | Emerging Infect. Dis. | pmid:9011381 |
| Buche A et al. | Interaction between ATP, oleandomycin and the OleB ATP-binding cassette transporter of Streptomyces antibioticus involved in oleandomycin secretion. | 1997 | Biochem. J. | pmid:9003412 |
| Hernández JM et al. | Clinical efficacy of dirithromycin in patients with bacteremic pneumonia. | 1996 Nov-Dec | Clin Ther | pmid:9001829 |
| Vanhoof R et al. | In vitro susceptibilities of 176 clinical isolates of Streptococcus pneumoniae to 11 beta-lactams, erythromycin, and tetracycline. | 1996 | Acta Clin Belg | pmid:8997755 |
| Yamada K et al. | Electrophysiological characterization of a motilin agonist, GM611, on rabbit duodenal smooth muscle. | 1996 | Am. J. Physiol. | pmid:8997244 |
| Ross JI et al. | Minimal functional system required for expression of erythromycin resistance by msrA in Staphylococcus aureus RN4220. | 1996 | Gene | pmid:8996099 |
| Kane GC | Legionella species community-acquired pneumonia. | 1997 | Chest | pmid:8996030 |
| GarcÃa de Lomas J et al. | [Activity of erythromycin and clarithromicin against isolates of Streptococcus pneumoniae with decreased sensitivity to penicillin obtained from healty carriers. Spanish Collaborative Group]. | 1996 Aug-Sep | Enferm. Infecc. Microbiol. Clin. | pmid:8991436 |
| Lakritz J et al. | Effect of treatment with erythromycin on bronchoalveolar lavage fluid cell populations in foals. | 1997 | Am. J. Vet. Res. | pmid:8989497 |
| Johnson DM and Jones RN | Two investigational glycylcyclines, DMG-DMDOT and DMG-MINO. Antimicrobial activity studies against gram-positive species. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8988765 |
| Wille KK et al. | Replicate plating: does it increase reliability? | 1996 | Lett. Appl. Microbiol. | pmid:8987446 |