| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Bone Resorption | D001862 | 7 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ogawa T et al. | [Effect of erythromycin on early delayed gastric emptying after pylorus preserving pancreatoduodenectomy--case report]. | 1996 | Nihon Shokakibyo Gakkai Zasshi | pmid:8865759 |
| Xu G et al. | Effect of macrolide antibiotics on macrophage functions. | 1996 | Microbiol. Immunol. | pmid:8865152 |
| Burnens AP et al. | Sequential development of resistance to fluoroquinolones and erythromycin in an isolate of Campylobacter jejuni. | 1996 | Zentralbl. Bakteriol. | pmid:8861869 |
| Lacey RW | Lack of evidence for mutation to erythromycin resistance in clinical strains of Staphylococcus aureus. | 1977 | J. Clin. Pathol. | pmid:886013 |
| Vanakoski J et al. | Grapefruit juice does not enhance the effects of midazolam and triazolam in man. | 1996 | Eur. J. Clin. Pharmacol. | pmid:8858279 |
| Watkins PB | Erythromycin breath test and clinical transplantation. | 1996 | Ther Drug Monit | pmid:8857552 |
| Hofstetter A | [Mycoplasma infections of urogenital tract]. | 1977 | Hautarzt | pmid:885718 |
| Raab W | [Acute side effects of erythromycin, lincomycin and clindamycin]. | 1977 | Int J Clin Pharmacol Biopharm | pmid:885668 |
| Chang AD et al. | Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). | 1996 | Am. J. Gastroenterol. | pmid:8855753 |
| Vermot D et al. | Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis. | 1996 | Antimicrob. Agents Chemother. | pmid:8851620 |
| Amsden GW | Erythromycin, clarithromycin, and azithromycin: are the differences real? | 1996 Jan-Feb | Clin Ther | pmid:8851453 |
| Wondrack L et al. | Clinical strain of Staphylococcus aureus inactivates and causes efflux of macrolides. | 1996 | Antimicrob. Agents Chemother. | pmid:8849266 |
| Weiss K et al. | Comparison of antimicrobial susceptibilities of Corynebacterium species by broth microdilution and disk diffusion methods. | 1996 | Antimicrob. Agents Chemother. | pmid:8849254 |
| Masuda N et al. | Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa. | 1996 | Antimicrob. Agents Chemother. | pmid:8849250 |
| Doern GV et al. | Emergence of high rates of antimicrobial resistance among viridans group streptococci in the United States. | 1996 | Antimicrob. Agents Chemother. | pmid:8849246 |
| O'Hara K and Yamamoto K | Reaction of roxithromycin and clarithromycin with macrolide-inactivating enzymes from highly erythromycin-resistant Escherichia coli. | 1996 | Antimicrob. Agents Chemother. | pmid:8849224 |
| Kim KH et al. | Periauricular eczematization in childhood atopic dermatitis. | 1996 Jul-Aug | Pediatr Dermatol | pmid:8844743 |
| Shryock TR et al. | Minimum inhibitory concentration breakpoints and disk diffusion inhibitory zone interpretive criteria for tilmicosin susceptibility testing against Pasteurella spp. associated with bovine respiratory disease. | 1996 | J. Vet. Diagn. Invest. | pmid:8844577 |
| Ednie LM et al. | Comparative activities of clarithromycin, erythromycin, and azithromycin against penicillin-susceptible and penicillin-resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8843313 |
| Sutcliffe J et al. | Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. | 1996 | Antimicrob. Agents Chemother. | pmid:8843287 |
| Vaara M and Porro M | Group of peptides that act synergistically with hydrophobic antibiotics against gram-negative enteric bacteria. | 1996 | Antimicrob. Agents Chemother. | pmid:8843284 |
| Tschida SJ et al. | QTc-interval prolongation associated with slow intravenous erythromycin lactobionate infusions in critically ill patients: a prospective evaluation and review of the literature. | 1996 Jul-Aug | Pharmacotherapy | pmid:8840374 |
| Viravan C et al. | A prospective clinical and bacteriologic study of inguinal buboes in Thai men. | 1996 | Clin. Infect. Dis. | pmid:8838178 |
| Schierholz JM et al. | Drug delivery concepts for the efficacious prevention of foreign-body infections. | 1996 | Zentralbl. Bakteriol. | pmid:8837400 |
| Chapuis C et al. | An economic approach to the MIC. | 1996 | Zentralbl. Bakteriol. | pmid:8837370 |
| Ehret JM et al. | A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. | 1996 Jul-Aug | Sex Transm Dis | pmid:8836018 |
| Lanbeck P and Paulsen O | Cytotoxic effects of four antibiotics on endothelial cells. | 1995 | Pharmacol. Toxicol. | pmid:8835360 |
| Roseghini M et al. | Choline esters and biogenic amines in the hypobranchial gland of 55 molluscan species of the neogastropod Muricoidea superfamily. | 1996 | Toxicon | pmid:8835333 |
| Cooper AJ et al. | The erythromycin resistance gene from the Bacteroides conjugal transposon Tcr Emr 7853 is nearly identical to ermG from Bacillus sphaericus. | 1996 | Antimicrob. Agents Chemother. | pmid:8834912 |
| Edelstein PH et al. | Activity of trovafloxacin (CP-99,219) against Legionella isolates: in vitro activity, intracellular accumulation and killing in macrophages, and pharmacokinetics and treatment of guinea pigs with L. pneumophila pneumonia. | 1996 | Antimicrob. Agents Chemother. | pmid:8834872 |
| Luo G et al. | Erythromycin biosynthesis: exploiting the catalytic versatility of the modular polyketide synthase. | 1996 | Bioorg. Med. Chem. | pmid:8831969 |
| Liu J et al. | Inhibitory effect of erythromycin on ion transport by stria vascularis and vestibular dark cells. | 1996 | Acta Otolaryngol. | pmid:8831844 |
| Enomoto F et al. | [Evaluation of the effect of erythromycin on otitis media with effusion in experimental rat models]. | 1996 | Nippon Jibiinkoka Gakkai Kaiho | pmid:8831236 |
| Biedenbach DJ and Jones RN | The comparative antimicrobial activity of levofloxacin tested against 350 clinical isolates of streptococci. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8831045 |
| Hong T et al. | Direct application of Etest to gram-positive cocci from blood cultures: quick and reliable minimum inhibitory concentration data. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8831041 |
| Donadio S et al. | Erythromycin production in Saccharopolyspora erythraea does not require a functional propionyl-CoA carboxylase. | 1996 | Mol. Microbiol. | pmid:8830278 |
| Barrio J et al. | Rosacea-like demodicosis in an HIV-positive child. | 1996 | Dermatology (Basel) | pmid:8829498 |
| Steele RW | Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis. | 1996 | Clin Pediatr (Phila) | pmid:8829012 |
| Deguchi K et al. | [Antimicrobial activities of cefozopran against Streptococcus pneumoniae from children]. | 1996 | Jpn J Antibiot | pmid:8828071 |
| Scrivener CJ and Vizard AL | Efficacy of a single dose of erythromycin or penicillin/streptomycin for the treatment of ovine dermatophilosis. | 1995 | Aust. Vet. J. | pmid:8825319 |
| Zhang XJ and Thomas PE | Erythromycin as a specific substrate for cytochrome P4503A isozymes and identification of a high-affinity erythromycin N-demethylase in adult female rats. | 1996 | Drug Metab. Dispos. | pmid:8825186 |
| Brunner H | [Pneumonia caused by mycoplasma pneumoniae. On the differential diagnosis of acute pneumonias (author's transl)]. | 1977 | Schweiz. Rundsch. Med. Prax. | pmid:882509 |
| Funabashi Y et al. | Microbial conversion of EM574 and EM523, gastrointestinal motor stimulating agents. | 1996 | J. Antibiot. | pmid:8823514 |
| Funabashi Y et al. | Bioactive metabolites of EM574 and EM523, erythromycin derivatives having strong gastrointestinal motor stimulating activity. | 1996 | J. Antibiot. | pmid:8823513 |
| Kao CM et al. | Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase. | 1996 | Biochemistry | pmid:8823171 |
| Wang Y et al. | RNA molecules that specifically and stoichiometrically bind aminoglycoside antibiotics with high affinities. | 1996 | Biochemistry | pmid:8823168 |
| Steiner A and Roussel AJ | Drugs coordinating and restoring gastrointestinal motility and their effect on selected hypodynamic gastrointestinal disorders in horses and cattle. | 1995 | Zentralbl Veterinarmed A | pmid:8822186 |
| Luurila H et al. | Interaction between erythromycin and the benzodiazepines diazepam and flunitrazepam. | 1996 | Pharmacol. Toxicol. | pmid:8822046 |
| Müller-Wening W et al. | [Clinical and radiological findings in 78 children during the 1974/75 mycoplasma-pneumonia-epidemic (author's transl)]. | 1977 | Monatsschr Kinderheilkd | pmid:882103 |
| Enhanced surveillance of non-toxigenic Corynebacterium diphtheriae infections. | 1996 | Commun Dis Rep CDR Wkly | pmid:8821021 |