erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Zhou D and Apicella MA Plasmids with erythromycin resistance and catechol 2,3-dioxygenase- or beta-galactosidase-encoding gene cassettes for use in Neisseria spp. 1996 Gene pmid:8675023
Surrenti E et al. Antral axial forces postprandially and after erythromycin in organic and functional dysmotilities. 1996 Dig. Dis. Sci. pmid:8674390
Nikulin KG [Treatment of acute pneumonia at different stages of the disease]. 1977 Ter. Arkh. pmid:867244
McMeekin TO and Moschella SL Iatrogenic complications of dermatologic therapy. Primum non nocere. 1979 Med. Clin. North Am. pmid:86664
Lode H et al. Treatment of community-acquired pneumonia: a randomized comparison of sparfloxacin, amoxycillin-clavulanic acid and erythromycin. 1995 Eur. Respir. J. pmid:8666093
Johnson AP et al. Prevalence of antibiotic resistance and serotypes in pneumococci in England and Wales: results of observational surveys in 1990 and 1995. 1996 BMJ pmid:8664623
Aleksandrova AE and Vinogradova TI [Immunotropic activity of antimicrobial agents used in tuberculosis]. 1996 Probl Tuberk pmid:8657696
King DE et al. Effectiveness of erythromycin in the treatment of acute bronchitis. 1996 J Fam Pract pmid:8656171
Packman AM et al. Treatment of acne vulgaris: combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion. 1996 Int. J. Dermatol. pmid:8655242
Kligman AM The treatment of acne. Part III: antibacterials. 1995 Cutis pmid:8654122
Mashkilleyson AL et al. Treatment of syphilis with azithromycin. 1996 Int J STD AIDS pmid:8652720
Pieper R et al. Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates. 1996 Biochemistry pmid:8652546
Vickery CL et al. Bacillary angiomatosis presenting as a nasal mass with epistaxis. 1996 Otolaryngol Head Neck Surg pmid:8649879
Dam M et al. Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance. 1996 J. Mol. Biol. pmid:8648637
Yasui N et al. A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism. 1996 Clin. Pharmacol. Ther. pmid:8646822
Belousov IuB et al. [Dirithromycin in the treatment of infections of the lower respiratory tract]. 1995 Antibiot. Khimioter. pmid:8645058
Tenson T et al. A functional peptide encoded in the Escherichia coli 23S rRNA. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8643630
Gerber MA Antibiotic resistance: relationship to persistence of group A streptococci in the upper respiratory tract. 1996 Pediatrics pmid:8637784
Stopler T et al. [Mycoplasma pneumoniae infections in families in Jerusalem and in kibbutzim]. 1977 Harefuah pmid:863299
Fang CC et al. Erythromycin-induced acute pancreatitis. 1996 J. Toxicol. Clin. Toxicol. pmid:8632521
Cohen LG et al. Erythromycin-induced clozapine toxic reaction. 1996 Arch. Intern. Med. pmid:8629881
Huang XM et al. Base decomposition of erythromycin A methoxime. 1996 J. Antibiot. pmid:8626251
Plaza MA et al. Effect of motilin, somatostatin and bombesin on gastroduodenal myoelectric activity in sheep. 1996 Life Sci. pmid:8622567
Noguchi N et al. Nucleotide sequence and characterization of erythromycin resistance determinant that encodes macrolide 2'-phosphotransferase I in Escherichia coli. 1995 Antimicrob. Agents Chemother. pmid:8619599
Hsueh PR et al. Decreased activity of erythromycin against Streptococcus pyogenes in Taiwan. 1995 Antimicrob. Agents Chemother. pmid:8619575
Miller RD and Fung DY The excretion of enterotoxin B from nongrowing cells of Staphylococcus aureus 4916. 1977 Can. J. Microbiol. pmid:861845
Tzovaras G et al. The effect of intravenous erythromycin on esophageal motility in healthy subjects. 1996 Am. J. Surg. pmid:8615464
Blumenfeld H et al. Trimethoprim and sulfonamide-associated meningoencephalitis with MRI correlates. 1996 Neurology pmid:8614533
Thompson D and Oster G Use of terfenadine and contraindicated drugs. 1996 JAMA pmid:8614120
Harris RZ et al. The effects of menopause and hormone replacement therapies on prednisolone and erythromycin pharmacokinetics. 1996 Clin. Pharmacol. Ther. pmid:8612388
Feierman DE Identification of cytochrome P450 3A1/2 as the major P450 isoform responsible for the metabolism of fentanyl by rat liver microsomes. 1996 Anesth. Analg. pmid:8610902
Kadota J et al. Significance of IL-1beta and IL-1 receptor antagonist (IL-1Ra) in bronchoalveolar lavage fluid (BALF) in patients with diffuse panbronchiolitis (DPB). 1996 Clin. Exp. Immunol. pmid:8608647
Oberg KC and Bauman JL QT interval prolongation and torsades de pointes due to erythromycin lactobionate. 1995 Nov-Dec Pharmacotherapy pmid:8602374
Avila-Campos MJ et al. Distribution of biotypes and antimicrobial susceptibility of Actinobacillus actinomycetemcomitans. 1995 Oral Microbiol. Immunol. pmid:8602348
Burt M et al. Erythromycin stimulates gastric emptying after esophagectomy with gastric replacement: a randomized clinical trial. 1996 J. Thorac. Cardiovasc. Surg. pmid:8601981
Westh H Erythromycin-resistant Staphylococcus aureus in Denmark. 1996 APMIS Suppl. pmid:8600946
The choice of antibacterial drugs. 1996 Med Lett Drugs Ther pmid:8598824
Schachter J and Dawson CR Is trachoma an ocular component of a more generalised chlamydial infection? 1979 Lancet pmid:85939
Vasilos LV et al. [Chemotherapeutic effectiveness of erythromycin, rifampicin and tetracyclines in chlamydiosis and mycoplasmosis in children]. 1995 Antibiot. Khimioter. pmid:8593094
Lucier TS et al. Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae. 1995 Antimicrob. Agents Chemother. pmid:8593017
Bental T et al. Chronic Q fever of pregnancy presenting as Coxiella burnetii placentitis: successful outcome following therapy with erythromycin and rifampin. 1995 Clin. Infect. Dis. pmid:8589167
Lavy E et al. Minimal inhibitory concentrations for canine isolates and oral absorption of roxythromycin in fed and fasted dogs. 1995 J. Vet. Pharmacol. Ther. pmid:8587159
Radulovic S et al. In vitro and in vivo antibiotic susceptibilities of ELB rickettsiae. 1995 Antimicrob. Agents Chemother. pmid:8585746
Hamzehpour MM et al. OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa. 1995 Antimicrob. Agents Chemother. pmid:8585714
De Serres G et al. Field effectiveness of erythromycin prophylaxis to prevent pertussis within families. 1995 Pediatr. Infect. Dis. J. pmid:8584364
Bortolussi R et al. Clinical course of pertussis in immunized children. 1995 Pediatr. Infect. Dis. J. pmid:8584314
Tinanoff N et al. Dental treatment of Papillon-Lefèvre syndrome: 15-year follow-up. 1995 J. Clin. Periodontol. pmid:8583017
Minocha A et al. Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. 1995 Aliment. Pharmacol. Ther. pmid:8580273
Slomiany BL et al. Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents. 1995 Scand. J. Gastroenterol. Suppl. pmid:8578215
Masclee AA et al. Effect of antrectomy and truncal vagotomy on erythromycin induced pancreatic polypeptide secretion. 1995 Regul. Pept. pmid:8577928