| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Bone Resorption | D001862 | 7 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gaillat J | [Objectives for antibiotic therapy in acute exacerbations of chronic bronchitis]. | 2001 | Presse Med | pmid:11721486 |
| Goldschmidt N et al. | Compound cardiac toxicity of oral erythromycin and verapamil. | 2001 | Ann Pharmacother | pmid:11724091 |
| Maniatis AN et al. | Dissemination of clonally unrelated erythromycin- and glycopeptide-resistant Enterococcus faecium isolates in a tertiary Greek hospital. | 2001 | J. Clin. Microbiol. | pmid:11724887 |
| Meyer RD | [Legionaire's disease (author's transl)]. | 1979 | MMW Munch Med Wochenschr | pmid:117313 |
| Asai T et al. | Pre-operative oral erythromycin reduces residual gastric volume and acidity. | 2000 | Br J Anaesth | pmid:11732520 |
| Kunin CM | Letter: Erythromycin in staphylococcal infections. | 1975 | JAMA | pmid:1173378 |
| Espinosa de los Monteros LE et al. | Outbreak of scarlet fever caused by an erythromycin-resistant Streptococcus pyogenes emm22 genotype strain in a day-care center. | 2001 | Pediatr. Infect. Dis. J. | pmid:11734748 |
| Syrogiannopoulos GA et al. | High prevalence of erythromycin resistance of Streptococcus pyogenes in Greek children. | 2001 | Pediatr. Infect. Dis. J. | pmid:11734765 |
| Brinberg SL et al. | [Dependence of erythromycin biosynthesis on the active acidity of the medium]. | 1976 | Antibiotiki | pmid:11737 |
| Nogami K et al. | Intravenous low-dose erythromycin administration for infants with feeding intolerance. | 2001 | Pediatr Int | pmid:11737737 |
| Johnson CN et al. | In vitro activity of ABT-773, telithromycin and eight other antimicrobials against erythromycin-resistant Streptococcus pneumoniae respiratory isolates of children. | 2001 | Int. J. Antimicrob. Agents | pmid:11738340 |
| Hayney MS et al. | Effect of influenza immunization on CYP3A4 activity. | 2001 | Vaccine | pmid:11738750 |
| Lebel MH and Mehra S | Efficacy and safety of clarithromycin versus erythromycin for the treatment of pertussis: a prospective, randomized, single blind trial. | 2001 | Pediatr. Infect. Dis. J. | pmid:11740322 |
| Stocks SM and Thomas CR | Viability, strength, and fragmentation of Saccharopolyspora erythraea in submerged fermentation. | 2001 | Biotechnol. Bioeng. | pmid:11745148 |
| Frykman S et al. | Precursor-directed production of erythromycin analogs by Saccharopolyspora erythraea. | 2001 | Biotechnol. Bioeng. | pmid:11745157 |
| Ho PL et al. | Fluoroquinolone resistance among Streptococcus pneumoniae in Hong Kong linked to the Spanish 23F clone. | 2001 Sep-Oct | Emerging Infect. Dis. | pmid:11747711 |
| Honma Y et al. | Enhanced anti-Shigella activity of erythromycin supplemented with sulfadiazine. | 2001 | FEMS Immunol. Med. Microbiol. | pmid:11750221 |
| Benedetti E et al. | Treatment of severe pneumonia in kidney transplant recipients. | 2001 Nov-Dec | Transplant. Proc. | pmid:11750552 |
| von Eiff C and Peters G | Comparative in vitro activity of ABT-773 and two macrolides against staphylococci. | 2002 | J. Antimicrob. Chemother. | pmid:11751787 |
| Kaul A | Erythromycin as a prokinetic agent. | 2002 | J. Pediatr. Gastroenterol. Nutr. | pmid:11753157 |
| Jadcherla SR and Berseth CL | Effect of erythromycin on gastroduodenal contractile activity in developing neonates. | 2002 | J. Pediatr. Gastroenterol. Nutr. | pmid:11753158 |
| Costalos C et al. | Erythromycin as a prokinetic agent in preterm infants. | 2002 | J. Pediatr. Gastroenterol. Nutr. | pmid:11753159 |
| RodrÃguez-Avial C et al. | [Susceptibility to penicillin and 13 antimicrobial agents in erythromycin-resistant viridans group streptococci isolated from blood cultures]. | 2001 | Rev Esp Quimioter | pmid:11753449 |
| Lumio J et al. | Epidemiology of three cases of severe diphtheria in Finnish patients with low antitoxin antibody levels. | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11757971 |
| Sasaki M et al. | Erythromycin and clarithromycin modulation of growth factor-induced expression of heparanase mRNA on human lung cancer cells in vitro. | 2001 | Mediators Inflamm. | pmid:11759110 |
| Aanpreung P and Vajaradul C | Clinical use of erythromycin in children with gastrointestinal dysmotility. | 2001 | J Med Assoc Thai | pmid:11759961 |
| Petermann W et al. | A prospective, randomized, multicenter comparative study of clinafloxacin versus a ceftriaxone-based regimen in the treatment of hospitalized patients with community-acquired pneumonia. | 2001 | Scand. J. Infect. Dis. | pmid:11760164 |
| Gür D et al. | Streptococcus pneumoniae penicillin resistance in Turkey. | 2001 | J Chemother | pmid:11760219 |
| Aziz EE et al. | Risk factors for the development of Clostridium difficile toxin-associated diarrhoea: a pilot study. | 2001 Jun-Jul | Pharmacoepidemiol Drug Saf | pmid:11760491 |
| Parsons RL et al. | The absorption of antibiotics in adult patients with coeliac disease. | 1975 | J. Antimicrob. Chemother. | pmid:1176375 |
| Hardee PG et al. | Staphylococcal submandibular lymphadentitis of childhood. | 2001 | J Ir Dent Assoc | pmid:11764643 |
| Bingen E | [Microbiology in acute otitis media]. | 1998 | Rev Prat | pmid:11767328 |
| Coventry DR and Dilworth MJ | Inhibition of protein synthesis by D-threo-chloramphenicol in the laboratory and nodule forms of Rhizobium lupini. | 1975 | J. Gen. Microbiol. | pmid:1176963 |
| GarcÃa-Rey C et al. | Importance of local variations in antibiotic consumption and geographical differences of erythromycin and penicillin resistance in Streptococcus pneumoniae. | 2002 | J. Clin. Microbiol. | pmid:11773111 |
| Holbrook MA and Menninger JR | Erythromycin slows aging of Saccharomyces cerevisiae. | 2002 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:11773204 |
| Richter SS et al. | The molecular epidemiology of penicillin-resistant Streptococcus pneumoniae in the United States, 1994-2000. | 2002 | Clin. Infect. Dis. | pmid:11774080 |
| Coyle MB et al. | Erythromycin and clindamycin resistance in Corynebacterium diphtheriae from skin lesions. | 1979 | Antimicrob. Agents Chemother. | pmid:117748 |
| Liu J et al. | [mRNA expression of basic fibroblast growth factor in the pulmonary tissues from rats repeatedly infected with mycoplasma pneumoniae]. | 1999 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11775917 |
| PrÃncipe RodrÃguez K and RodrÃguez Cintrón W | Legionnaires' disease: a rare entity in Puerto Rico? | 2001 | P R Health Sci J | pmid:11776727 |
| Li Y et al. | [The effect of erythromycin on NF-kappa B activation and cytokines mRNA expression in bleomycin-induced pulmonary fibrosis in rats]. | 1999 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11776779 |
| Xiao W et al. | [The imbalance of Th1/Th2 cytokine expression in peripheral blood mononuclear cell from asthmatic patients and the effect of erythromycin on these cytokines]. | 2000 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11778516 |
| Matsuura B et al. | Differential determinants for peptide and non-peptidyl ligand binding to the motilin receptor. Critical role of second extracellular loop for peptide binding and action. | 2002 | J. Biol. Chem. | pmid:11781320 |
| Wilkowske CJ and Hermans PE | Actions and uses of antimicrobial agents in the treatment of musculoskeletal infections. | 1975 | Orthop. Clin. North Am. | pmid:1178163 |
| Gan G et al. | Intestinal absorption and presystemic elimination of the prokinetic agent, EM574, in the rabbit. | 2002 | J Pharm Sci | pmid:11782911 |
| del Castillo F et al. | Penicillin-susceptible and erythromycin-resistant Streptococcus pneumoniae in children with acute mastoiditis. | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11783702 |
| Hertweck M et al. | Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. | 2002 | Eur. J. Biochem. | pmid:11784311 |
| Shibuya Y et al. | The effect of erythromycin on mucociliary transportability and rheology of cystic fibrosis and bronchiectasis sputum. | 2001 | Respiration | pmid:11786718 |
| Fuchs PC et al. | Selection of zone size interpretive criteria for disk diffusion susceptibility tests of three antibiotics against Streptococcus pneumoniae, using the New Guidelines of the National Committee for Clinical Laboratory Standards. | 2002 | Antimicrob. Agents Chemother. | pmid:11796348 |
| Nagai K et al. | Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries. | 2002 | Antimicrob. Agents Chemother. | pmid:11796375 |
| Guerin JM and Leibinger F | Why not to use erythromycin in GI motility. | 2002 | Chest | pmid:11796472 |