erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Chen J et al. [An experimental study on the effect of azithromycin treatment in bleomycin-induced pulmonary fibrosis of rats]. 1999 Zhonghua Nei Ke Za Zhi pmid:11798706
Abouesh A et al. Antimicrobial-induced mania (antibiomania): a review of spontaneous reports. 2002 J Clin Psychopharmacol pmid:11799346
Rollins G Single antibiotic therapy as effective as dual in treating patients hospitalized with community acquired pneumonia. 2000 Rep Med Guidel Outcomes Res pmid:11799995
Cid A et al. Recurrent bacteremia caused by Rhodococcus equi in a non-neutropenic patient with acute myeloid leukemia in complete remission. 2002 Haematologica pmid:11801477
Xu Z et al. [Effects of erythromycin and fosfomycin on Pseudomonas aeruginosa biofilm in vitro]. 2001 Zhonghua Jie He He Hu Xi Za Zhi pmid:11802985
Belizhenko GG [Effect of trypsin on the activity of tetracycline, erythromycin and levomycetin]. 1975 Antibiotiki pmid:1180534
Kamagate A et al. [A comparative study of various evaluation methods of the antibiotic sensitivity of strict anaerobic bacteria of the subgingival flora]. 2001 Odontostomatol Trop pmid:11808376
Basak PY et al. The effect of benzoyl peroxide and benzoyl peroxide/erythromycin combination on the antioxidative defence system in papulopustular acne. 2002 Jan-Feb Eur J Dermatol pmid:11809596
Tateda K et al. Potential of macrolide antibiotics to inhibit protein synthesis of Pseudomonas aeruginosa: suppression of virulence factors and stress response. 2000 J. Infect. Chemother. pmid:11810524
Mitsuya Y et al. Influence of macrolides on guanosine diphospho-D-mannose dehydrogenase activity in Pseudomonas biofilm. 2000 J. Infect. Chemother. pmid:11810531
Li M et al. In-vitro and in-vivo antibiotic susceptibilities of Lyme disease Borrelia isolated in China. 2000 J. Infect. Chemother. pmid:11810535
Lee K et al. Trends in serotypes and antimicrobial susceptibility of group B streptococci isolated in Korea. 2000 J. Infect. Chemother. pmid:11810542
Kunishima H et al. Evaluation of the activity of antimicrobial agents against Legionella pneumophila multiplying in a human monocytic cell line, THP-1, and an alveolar epithelial cell line, A549. 2000 J. Infect. Chemother. pmid:11810567
Tan W et al. [The mechanism and effect of erythromycin in development of pulmonary fibrosis]. 1999 Zhonghua Jie He He Hu Xi Za Zhi pmid:11812357
Depoortere I Motilin and motilin receptors: characterization and functional significance. 2001 Verh. K. Acad. Geneeskd. Belg. pmid:11813507
Vorbach H et al. Endothelial cell compatibility of azithromycin and erythromycin. 2002 J. Antimicrob. Chemother. pmid:11815590
Bradley C Erythromycin as a gastrointestinal prokinetic agent. 2001 Intensive Crit Care Nurs pmid:11817442
Xuan D et al. Pharmacokinetics of ABT-773, a new semi-synthetic ketolide in neutropenic lung-infected mice: a population approach. 2002 J. Pharm. Pharmacol. pmid:11829132
Visudhiphan P and Chiemchanya S Mima polymorpha ventriculitis in a young infant. Problems in overcoming the infection with erythromycin intraventricularly. 1975 Clin Pediatr (Phila) pmid:1183131
Weitnauer G et al. Analysis of a C-methyltransferase gene (aviG1) involved in avilamycin biosynthesis in Streptomyces viridochromogenes Tü57 and complementation of a Saccharopolyspora erythraea eryBIII mutant by aviG1. 2002 Microbiology (Reading, Engl.) pmid:11832501
Goodchild C et al. Antimicrobial susceptibility of Campylobacter species. 2001 N. Z. Med. J. pmid:11833968
Edder P et al. Analysis of erythromycin and oleandomycin residues in food by high-performance liquid chromatography with fluorometric detection. 2002 Food Addit Contam pmid:11834075
Krishnan P et al. Diffuse panbronchiolitis: a treatable sinobronchial disease in need of recognition in the United States. 2002 Chest pmid:11834689
Kawakami K et al. Assessment of amorphous content by microcalorimetry. 2002 J Pharm Sci pmid:11835201
Gaylor AS and Reilly JC Therapy with macrolides in patients with cystic fibrosis. 2002 Pharmacotherapy pmid:11837560
Petrakis IE et al. Hyperglycemia attenuates erythromycin-induced acceleration of liquid-phase gastric emptying of hypertonic liquids in healthy subjects. 2002 Dig. Dis. Sci. pmid:11837735
Cane DE et al. Precursor-directed biosynthesis: biochemical basis of the remarkable selectivity of the erythromycin polyketide synthase toward unsaturated triketides. 2002 Chem. Biol. pmid:11841945
Nieto JE et al. Use of an extracorporeal circuit to evaluate effects of intraluminal distention and decompression on the equine jejunum. 2002 Am. J. Vet. Res. pmid:11843129
LeMahieu RA et al. A facile preparation or erythronolide A oxime. 1975 J. Antibiot. pmid:1184479
Mizukane R et al. An elderly patient with hemophagocytic syndrome due to severe mycoplasma pneumonia with marked hypercytokinemia. 2002 Respiration pmid:11844970
Speciale A et al. Minimal inhibitory concentrations and time-kill determination of moxifloxacin against aerobic and anaerobic isolates. 2002 Int. J. Antimicrob. Agents pmid:11850163
Shortridge VD et al. Comparison of in vitro activities of ABT-773 and telithromycin against macrolide-susceptible and -resistant streptococci and staphylococci. 2002 Antimicrob. Agents Chemother. pmid:11850262
McDermott JS et al. Importance of species selection in arrythmogenic models of Q-T interval prolongation. 2002 Antimicrob. Agents Chemother. pmid:11850295
Uh Y et al. Penicillin-resistant Aerococcus viridans bacteremia associated with granulocytopenia. 2002 J. Korean Med. Sci. pmid:11850599
Swart EL et al. Correlation between midazolam and lignocaine pharmacokinetics and MEGX formation in healthy volunteers. 2002 Br J Clin Pharmacol pmid:11851636
Louik C et al. Erythromycin use during pregnancy in relation to pyloric stenosis. 2002 Am. J. Obstet. Gynecol. pmid:11854652
Rodríguez-Avial I et al. [In vitro activity of six fluoroquinolones and penicillin against 101 viridans group streptococci characterized by their susceptibility to erythromycin]. 2001 Rev Esp Quimioter pmid:11856983
Chou CC and Wu D Torsade de pointes induced by metoclopramide in an elderly woman with preexisting complete left bundle branch block. 2001 Chang Gung Med J pmid:11858397
Casellas JM et al. In vitro activity of the new ketolide ABT-773 against community acquired respiratory tract isolates and Viridans Streptococci. 2002 Diagn. Microbiol. Infect. Dis. pmid:11858905
Guchelaar HJ et al. Pharmacokinetic-pharmacodynamic modeling of the inhibitory effect of erythromycin on tumour necrosis factor-alpha and interleukin-6 production. 2001 Fundam Clin Pharmacol pmid:11860530
Yamakawa T et al. In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone. 2002 J. Antimicrob. Chemother. pmid:11864945
Karpova GV et al. Early and delayed effects of carboplatin on the blood system. 2001 Bull. Exp. Biol. Med. pmid:11865323
Lotgering FK et al. [Erythromycin in premature rupture of membranes beneficial to the health of the child]. 2002 Ned Tijdschr Geneeskd pmid:11865663
Sondheimer JM A question that won't go away. 2002 J. Pediatr. Gastroenterol. Nutr. pmid:11865812
Zhanel GG and Hoban DJ Ketolides in the treatment of respiratory infections. 2002 Expert Opin Pharmacother pmid:11866679
Wardell JN et al. Decreasing the hyphal branching rate of Saccharopolyspora erythraea NRRL 2338 leads to increased resistance to breakage and increased antibiotic production. 2002 Biotechnol. Bioeng. pmid:11870604
Mas MR et al. Comparison of effects of cholecystokinin and erythromycin on bile chemistry and gallstone formation in aged guinea pigs. 2002 Jan-Feb Indian J Gastroenterol pmid:11871842
Cui M et al. A density-functional study of the mechanism for the diastereoselective epoxidation of chiral allylic alcohols by the titanium peroxy complexes. 2002 J. Org. Chem. pmid:11871869
Muirhead GJ et al. The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers. 2002 Br J Clin Pharmacol pmid:11879258
Janowski T et al. Combined gnRH and PGF2alpha application in cows with endometritis puerperalis treated with antibiotics. 2001 Reprod. Domest. Anim. pmid:11885741