| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Bone Resorption | D001862 | 7 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (20)
- J. Antimicrob. Chemother. (9)
- Drug Metab. Dispos. (2)
- Others (20)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee SY et al. | 23S rRNA point mutation associated with erythromycin resistance in Treponema denticola. | 2002 | FEMS Microbiol. Lett. | pmid:11886748 |
| Versteegh FG et al. | [Perinatal pertussis: from mother to child]. | 2002 | Ned Tijdschr Geneeskd | pmid:11887627 |
| Chung WO et al. | Distribution of erm(F) and tet(Q) genes in 4 oral bacterial species and genotypic variation between resistant and susceptible isolates. | 2002 | J. Clin. Periodontol. | pmid:11895543 |
| Kodama H et al. | [Studies on the group A type 12 hemolytic streptococci (author's transl)]. | 1979 | Kansenshogaku Zasshi | pmid:119007 |
| Fowler SM et al. | CYP3A4 active site volume modification by mutagenesis of leucine 211. | 2002 | Drug Metab. Dispos. | pmid:11901100 |
| Chávez M et al. | Evaluation of the new VITEK 2 system for determination of the susceptibility of clinical isolates of Streptococcus pneumoniae. | 2002 | Chemotherapy | pmid:11901253 |
| Kobayashi K et al. | Fine structure of erythromycin-resistant, conditional asporogenous mutant of Bacillus subtilis 168. | 1979 | J Electron Microsc (Tokyo) | pmid:119024 |
| Moore BS and Hertweck C | Biosynthesis and attachment of novel bacterial polyketide synthase starter units. | 2002 | Nat Prod Rep | pmid:11902441 |
| Kuroha M et al. | Effects of altered plasma alpha-1-acid glycoprotein levels on pharmacokinetics of some basic antibiotics in pigs: simulation analysis. | 2001 | J. Vet. Pharmacol. Ther. | pmid:11903873 |
| Liau SS et al. | Pharmacological modulation of human gastric volumes demonstrated noninvasively using SPECT imaging. | 2001 | Neurogastroenterol. Motil. | pmid:11903914 |
| Viramontes BE et al. | Validation of a stable isotope gastric emptying test for normal, accelerated or delayed gastric emptying. | 2001 | Neurogastroenterol. Motil. | pmid:11903917 |
| Prieto J and Ramos C | [Questions and answers on the class effect]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:11904096 |
| Ajello M et al. | Anti-invasive activity of bovine lactoferrin towards group A streptococci. | 2002 | Biochem. Cell Biol. | pmid:11908635 |
| Schmitz FJ et al. | Molecular characterization of ketolide-resistant erm(A)-carrying Staphylococcus aureus isolates selected in vitro by telithromycin, ABT-773, quinupristin and clindamycin. | 2002 | J. Antimicrob. Chemother. | pmid:11909834 |
| Pendland SL et al. | In vitro bactericidal activity of ABT-773 and amoxicillin against erythromycin-susceptible and -resistant strains of Streptococcus pyogenes. | 2002 | J. Antimicrob. Chemother. | pmid:11909842 |
| Sène D et al. | [Legionellosis in HIV-1 infected patients. 4 case reports]. | 2002 | Presse Med | pmid:11913078 |
| Terzidou V and Bennett PR | Preterm labour. | 2002 | Curr. Opin. Obstet. Gynecol. | pmid:11914686 |
| Long PF et al. | Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase. | 2002 | Mol. Microbiol. | pmid:11918808 |
| More on erythromycin and pyloric stenosis. | 2002 | Arch. Dis. Child. | pmid:11919096 | |
| Walsh CT | Combinatorial biosynthesis of antibiotics: challenges and opportunities. | 2002 | Chembiochem | pmid:11921390 |
| Lauzurica R et al. | Tacrolimus-associated severe bilateral corneal ulcer after renal transplantation. | 2002 | Transplantation | pmid:11923710 |
| Hoffman CF et al. | A case report of bacillary angiomatosis in a patient infected with human immunodeficiency virus. | 2002 | Cutis | pmid:11926335 |
| Chen CL et al. | Efficacy of a motilin receptor agonist (ABT-229) for the treatment of gastro-oesophageal reflux disease. | 2002 | Aliment. Pharmacol. Ther. | pmid:11929393 |
| Fosse T et al. | High prevalence of cfxA beta-lactamase in aminopenicillin-resistant Prevotella strains isolated from periodontal pockets. | 2002 | Oral Microbiol. Immunol. | pmid:11929554 |
| Wang BY et al. | Genetic exchange between Treponema denticola and Streptococcus gordonii in biofilms. | 2002 | Oral Microbiol. Immunol. | pmid:11929558 |
| Kuriyama T et al. | Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections. | 2002 | Oral Microbiol. Immunol. | pmid:11929563 |
| Dellagrammaticas HD et al. | Effect of low-dose oral erythromycin on gastric aspirates in ventilated neonates less than 32 weeks of gestation. Preliminary results. | 2002 | Biol. Neonate | pmid:11937729 |
| Braga PC | Relationship between differences in 16-, 14-, and 15-membered ring macrolides and Streptococcus pyogenes resistance. | 2002 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11939399 |
| Andrisano V et al. | Stereoselective binding of 2-(4-biphenylyl)-3-substituted-3-hydroxypropionic acids on an immobilised human serum albumin chiral stationary phase. | 2002 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:11939547 |
| Liu F et al. | Establishment of multidrug-resistance cell line C(6)/adr and reversal of drug-resistance. | 2002 | Chin. Med. J. | pmid:11940340 |
| Nakabayashi T et al. | Gastropyloric motor activity and the effects of erythromycin given orally after esophagectomy. | 2002 | Am. J. Surg. | pmid:11943134 |
| Kurowski WM et al. | Factors influencing the formation and stability of D-glucoside 3-dehydrogenase activity in cultures of Agrobacterium tumefaciens. | 1975 | J. Gen. Microbiol. | pmid:1194891 |
| Nakamura H et al. | Effects of endogenous steroids on CYP3A4-mediated drug metabolism by human liver microsomes. | 2002 | Drug Metab. Dispos. | pmid:11950784 |
| Bryskier A | Viridans group streptococci: a reservoir of resistant bacteria in oral cavities. | 2002 | Clin. Microbiol. Infect. | pmid:11952717 |
| King A et al. | Erythromycin susceptibility of viridans streptococci from the normal throat flora of patients treated with azithromycin or clarithromycin. | 2002 | Clin. Microbiol. Infect. | pmid:11952721 |
| Suzuki T et al. | Erythromycin inhibits rhinovirus infection in cultured human tracheal epithelial cells. | 2002 | Am. J. Respir. Crit. Care Med. | pmid:11956054 |
| Okamoto H et al. | High frequency of erythromycin A resistance and distribution of mefE and ermB genes in clinical isolates of Streptococcus pneumoniae in Japan. | 2002 | J. Infect. Chemother. | pmid:11957116 |
| Farrow KA et al. | Identification of essential residues in the Erm(B) rRNA methyltransferase of Clostridium perfringens. | 2002 | Antimicrob. Agents Chemother. | pmid:11959553 |
| Culebras E et al. | Macrolide and tetracycline resistance and molecular relationships of clinical strains of Streptococcus agalactiae. | 2002 | Antimicrob. Agents Chemother. | pmid:11959603 |
| Winn PJ et al. | Comparison of the dynamics of substrate access channels in three cytochrome P450s reveals different opening mechanisms and a novel functional role for a buried arginine. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11959989 |
| Ekins S et al. | Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. | 2002 | Mol. Pharmacol. | pmid:11961113 |
| Martin JM et al. | Erythromycin-resistant group A streptococci in schoolchildren in Pittsburgh. | 2002 | N. Engl. J. Med. | pmid:11961148 |
| Huovinen P | Macrolide-resistant group a streptococcus--now in the United States. | 2002 | N. Engl. J. Med. | pmid:11961156 |
| Thiele J and Kvasnicka HM | CD34+ stem cells in chronic myeloproliferative disorders. | 2002 | Histol. Histopathol. | pmid:11962756 |
| Waugh AC and Long PF | Prospects for generating new antibiotics. | 2002 | Sci Prog | pmid:11969120 |
| Nissan A et al. | Direct inhibitory effect of erythromycin on human alimentary tract smooth muscle. | 2002 | Am. J. Surg. | pmid:11975929 |
| Fukuda M and Sasaki K | [Antibiotic ophthalmic solutions evaluated by pharmacokinetic parameters of maximum concentration in the aqueous]. | 2002 | Nippon Ganka Gakkai Zasshi | pmid:11979978 |
| Jones FE et al. | Experimental evaluation of "instant" preparation of the colon with povidone-iodine. | 1975 | Surg. Clin. North Am. | pmid:1198291 |
| Jarvest RL et al. | Nanomolar inhibitors of Staphylococcus aureus methionyl tRNA synthetase with potent antibacterial activity against gram-positive pathogens. | 2002 | J. Med. Chem. | pmid:11985462 |
| Biagi G et al. | Erythro- and threo-2-hydroxynonyl substituted 2-phenyladenines and 2-phenyl-8-azaadenines: ligands for A1 adenosine receptors and adenosine deaminase. | 2002 | Farmaco | pmid:11989801 |