erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Rello J et al. A three-year study of severe community-acquired pneumonia with emphasis on outcome. 1993 Chest pmid:8417885
Stassi D et al. Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis. 1993 J. Bacteriol. pmid:8416893
Pecevski J et al. The effect of erythromycin and its thiocarbamide derivative on the induction of meiotic chromosome rearrangements in irradiated male mice. 1977 Strahlentherapie pmid:841613
Arayne MS and Sultana N Erythromycin-antacid interaction. 1993 Pharmazie pmid:8415858
Paradisi M et al. Efficacy of topical erythromycin in treatment of perianal streptococcal dermatitis. 1993 Pediatr Dermatol pmid:8415314
Dan M and Feigl D Erythromycin-associated hypotension. 1993 Pediatr. Infect. Dis. J. pmid:8414782
Saitoh S et al. Mycoplasma pneumoniae infection may cause striatal lesions leading to acute neurologic dysfunction. 1993 Neurology pmid:8413990
Ahrens F et al. [Legionellosis in a newborn infant]. 1993 Monatsschr Kinderheilkd pmid:8413346
Holmberg K et al. Antimicrobial in vitro susceptibility of actinomyces israelii and arachnia propionica. 1977 Scand. J. Infect. Dis. pmid:841278
Lim KS et al. Antimicrobial susceptibility of bifidobacteria. 1993 J. Dairy Sci. pmid:8408866
Kobrehel G et al. 9a,11-cyclic carbamates of 15-membered azalides. 1993 J. Antibiot. pmid:8407586
Umeki S Anti-inflammatory action of erythromycin. Its inhibitory effect on neutrophil NADPH oxidase activity. 1993 Chest pmid:8404190
Hughes J and Burrows NP Infectious mononucleosis presenting as erythema multiforme. 1993 Clin. Exp. Dermatol. pmid:8403481
Rubart M et al. Electrophysiological mechanisms in a canine model of erythromycin-associated long QT syndrome. 1993 Circulation pmid:8403329
Zapp ML et al. Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production. 1993 Cell pmid:8402886
Navarro H et al. Effect of erythromycin on D-galactose absorption and sucrase activity in rabbit jejunum. 1993 Mar-Apr Can. J. Physiol. Pharmacol. pmid:8402381
Algeri A et al. Dependence of cytoplasmic on mitochondrial protein synthesis in K. lactis CBS 2360. II. Genetic studies. 1977 Mol. Gen. Genet. pmid:840224
Zennaro E et al. Dependence of cytoplasmic on mitochondrial protein synthesis in K. Lactis CBS 2360. I. Biochemical analysis. 1977 Mol. Gen. Genet. pmid:840223
Kenny GE and Cartwright FD Effect of pH, inoculum size, and incubation time on the susceptibility of Ureaplasma urealyticum to erythromycin in vitro. 1993 Clin. Infect. Dis. pmid:8399919
Waites KB et al. Therapeutic considerations for Ureaplasma urealyticum infections in neonates. 1993 Clin. Infect. Dis. pmid:8399918
Gallar P et al. Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin. 1993 Perit Dial Int pmid:8399560
Rumpianesi F et al. In vitro activity of azithromycin against Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis in comparison with erythromycin, roxithromycin and minocycline. 1993 J Chemother pmid:8396626
Weippl G Multicentre comparison of azithromycin versus erythromycin in the treatment of paediatric pharyngitis or tonsillitis caused by group A streptococci. 1993 J. Antimicrob. Chemother. pmid:8396103
Hamill J Multicentre evaluation of azithromycin and penicillin V in the treatment of acute streptococcal pharyngitis and tonsillitis in children. 1993 J. Antimicrob. Chemother. pmid:8396102
Schaad UB Multicentre evaluation of azithromycin in comparison with co-amoxiclav for the treatment of acute otitis media in children. 1993 J. Antimicrob. Chemother. pmid:8396101
Mohs E et al. A comparative study of azithromycin and amoxycillin in paediatric patients with acute otitis media. 1993 J. Antimicrob. Chemother. pmid:8396100
Daniel RR Comparison of azithromycin and co-amoxiclav in the treatment of otitis media in children. 1993 J. Antimicrob. Chemother. pmid:8396099
Mazzei T et al. Pharmacokinetics of azithromycin in patients with impaired hepatic function. 1993 J. Antimicrob. Chemother. pmid:8396098
Wildfeuer A et al. Comparison of the pharmacokinetics of three-day and five-day regimens of azithromycin in plasma and urine. 1993 J. Antimicrob. Chemother. pmid:8396097
Retsema JA et al. Preferential concentration of azithromycin in an infected mouse thigh model. 1993 J. Antimicrob. Chemother. pmid:8396096
Foulds G and Johnson RB Selection of dose regimens of azithromycin . 1993 J. Antimicrob. Chemother. pmid:8396095
Girard AE et al. The comparative activity of azithromycin, macrolides and amoxycillin against streptococci in experimental infections. 1993 J. Antimicrob. Chemother. pmid:8396094
Waugh MA Open study of the safety and efficacy of a single oral dose of azithromycin for the treatment of uncomplicated gonorrhoea in men and women. 1993 J. Antimicrob. Chemother. pmid:8396093
Lister PJ et al. Comparison of azithromycin and doxycycline in the treatment of non-gonococcal urethritis in men. 1993 J. Antimicrob. Chemother. pmid:8396092
Lauharanta J et al. Single-dose oral azithromycin versus seven-day doxycycline in the treatment of non-gonococcal urethritis in males. 1993 J. Antimicrob. Chemother. pmid:8396091
Fitzgeorge RB et al. A comparison of the efficacy of azithromycin and clarithromycin in oral therapy of experimental airborne Legionnaires' disease. 1993 J. Antimicrob. Chemother. pmid:8396090
Girard D et al. Comparison of azithromycin, roxithromycin, and cephalexin penetration kinetics in early and mature abscesses. 1993 J. Antimicrob. Chemother. pmid:8396089
Myburgh J et al. The efficacy and tolerance of a three-day course of azithromycin in the treatment of community-acquired pneumonia. 1993 J. Antimicrob. Chemother. pmid:8396088
Bradbury F Comparison of azithromycin versus clarithromycin in the treatment of patients with lower respiratory tract infection. 1993 J. Antimicrob. Chemother. pmid:8396087
Hoepelman AI et al. A single-blind comparison of three-day azithromycin and ten-day co-amoxiclav treatment of acute lower respiratory tract infections. 1993 J. Antimicrob. Chemother. pmid:8396086
Müller O Comparison of azithromycin versus clarithromycin in the treatment of patients with upper respiratory tract infections. 1993 J. Antimicrob. Chemother. pmid:8396085
Amaya-Tapia G et al. Once-daily azithromycin in the treatment of adult skin and skin-structure infections. 1993 J. Antimicrob. Chemother. pmid:8396084
Lo Bue AM et al. Efficacy of azithromycin compared with spiramycin in the treatment of odontogenic infections. 1993 J. Antimicrob. Chemother. pmid:8396083
Hopkins S Clinical safety and tolerance of azithromycin in children. 1993 J. Antimicrob. Chemother. pmid:8396082
Rodriguez-Solares A et al. A comparative study of the efficacy, safety and tolerance of azithromycin, dicloxacillin and flucloxacillin in the treatment of children with acute skin and skin-structure infections. 1993 J. Antimicrob. Chemother. pmid:8396081
Panteix G et al. In-vitro concentration of azithromycin in human phagocytic cells. 1993 J. Antimicrob. Chemother. pmid:8396080
Mansoor GA et al. Azithromycin-induced acute interstitial nephritis. 1993 Ann. Intern. Med. pmid:8395778
Gingras BA and Jensen JB Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. 1993 Am. J. Trop. Med. Hyg. pmid:8394660
Wathne B et al. Erythromycin versus metronidazole in the treatment of bacterial vaginosis. 1993 Acta Obstet Gynecol Scand pmid:8394627
Molinari G et al. Inhibition of Pseudomonas aeruginosa virulence factors by subinhibitory concentrations of azithromycin and other macrolide antibiotics. 1993 J. Antimicrob. Chemother. pmid:8392997