| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Bone Resorption | D001862 | 7 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Surgical Wound Infection | D013530 | 7 associated lipids |
| Abscess | D000038 | 13 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim BS et al. | An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis. | 2002 | Biochemistry | pmid:12196022 |
| Desaki M | [The effects of erythromycin and its derivative on the activation of transcription factors in human bronchial epithelial cells]. | 2002 | Jpn J Antibiot | pmid:12199116 |
| Laven RA and Hunt H | Evaluation of copper sulphate, formalin and peracetic acid in footbaths for the treatment of digital dermatitis in cattle. | 2002 | Vet. Rec. | pmid:12199433 |
| Kenyon S et al. | ORACLE--antibiotics for preterm prelabour rupture of the membranes: short-term and long-term outcomes. | 2002 | Acta Paediatr Suppl | pmid:12200889 |
| Maizumi N et al. | Quantitative comparison of the cytocidal effect of seven macrolide antibiotics on human periodontal ligament fibroblasts. | 2002 | J. Periodont. Res. | pmid:12200967 |
| Amezaga MR et al. | Molecular epidemiology of erythromycin resistance in Streptococcus pneumoniae isolates from blood and noninvasive sites. | 2002 | J. Clin. Microbiol. | pmid:12202572 |
| Weiss K et al. | Genotypic characterization of macrolide-resistant strains of Streptococcus pneumoniae isolated in Quebec, Canada, and in vitro activity of ABT-773 and telithromycin. | 2002 | J. Antimicrob. Chemother. | pmid:12205066 |
| Weber W et al. | Macrolide-based transgene control in mammalian cells and mice. | 2002 | Nat. Biotechnol. | pmid:12205509 |
| Bhoopathy S et al. | Characterization of quinidine 3-hydroxylation as a probe for the CYP 3A enzyme using a novel capillary electrophoresis technique. | 2002 | Eur J Pharm Sci | pmid:12208456 |
| Schindler R et al. | Vitamin A metabolism is altered in brown Norway and long-Evans rats infused with naftidrofuryl or erythromycin intravenously. | 2002 | Int J Vitam Nutr Res | pmid:12214558 |
| Gentilini E et al. | Antimicrobial susceptibility of coagulase-negative staphylococci isolated from bovine mastitis in Argentina. | 2002 | J. Dairy Sci. | pmid:12214983 |
| McNeill LA et al. | Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803. | 2002 | Biochem. J. | pmid:12215170 |
| Davydova N et al. | L22 ribosomal protein and effect of its mutation on ribosome resistance to erythromycin. | 2002 | J. Mol. Biol. | pmid:12225755 |
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| Marazzi P et al. | Clinical evaluation of Double Strength Isotrexin versus Benzamycin in the topical treatment of mild to moderate acne vulgaris. | 2002 | J Dermatolog Treat | pmid:12227873 |
| Sachs MS and Geballe AP | Biochemistry. Sense and sensitivity--controlling the ribosome. | 2002 | Science | pmid:12228706 |
| Ono H et al. | Drug resistance in Staphylococcus aureus. Induction of macrolide resistance by erythromycin, oleandomycin and their derivatives. | 1975 | Jpn. J. Microbiol. | pmid:1223337 |
| Pereyre S et al. | Mutations in 23S rRNA account for intrinsic resistance to macrolides in Mycoplasma hominis and Mycoplasma fermentans and for acquired resistance to macrolides in M. hominis. | 2002 | Antimicrob. Agents Chemother. | pmid:12234836 |
| Kim MK et al. | Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model. | 2002 | Antimicrob. Agents Chemother. | pmid:12234843 |
| Camilleri M | Motilin agonists and dyspepsia: throwing out the baby with the bath water. | 2002 | Gut | pmid:12235094 |
| Milberg P et al. | Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12235254 |
| Yasuda K et al. | Interaction of cytochrome P450 3A inhibitors with P-glycoprotein. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12235267 |
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| Palavecino EL et al. | Macrolide resistance phenotypes in Streptococcus pneumoniae in Santiago, Chile. | 2002 | Int. J. Antimicrob. Agents | pmid:12297359 |
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| Berne JD et al. | Erythromycin reduces delayed gastric emptying in critically ill trauma patients: a randomized, controlled trial. | 2002 | J Trauma | pmid:12352474 |
| Nelson K et al. | Cancer and chemotherapy-related upper gastrointestinal symptoms: the role of abnormal gastric motor function and its evaluation in cancer patients. | 2002 | Support Care Cancer | pmid:12353123 |
| Detcheva A et al. | Erythromycin-resistant group A streptococcal isolates recovered in Sofia, Bulgaria, from 1995 to 2001. | 2002 | J. Clin. Microbiol. | pmid:12354892 |
| Braga PC and Ricci D | Differences in the susceptibility of Streptococcus pyogenes to rokitamycin and erythromycin A revealed by morphostructural atomic force microscopy. | 2002 | J. Antimicrob. Chemother. | pmid:12356788 |
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| Mills O et al. | Bacterial resistance and therapeutic outcome following three months of topical acne therapy with 2% erythromycin gel versus its vehicle. | 2002 | Acta Derm. Venereol. | pmid:12361129 |
| Steinberg JM and Srugo I | Reoccurrence of culture-positive pertussis in an infant initially treated with azithromycin and steroids. | 2002 | Arch Pediatr Adolesc Med | pmid:12361458 |