erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Konturek JW and Domschke W [Gastroparesis--physiopathology, diagnosis and the latest therapy]. 1998 Dtsch. Med. Wochenschr. pmid:9556697
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Schwarz MI A man with dyspnea, productive cough, and chest radiograph showing hyperinflation and a diffuse nodular pattern. 1998 Chest pmid:9554657
Mortensen JE et al. In vitro activity of oral antimicrobial agents against clinical isolates of Pasteurella multocida. 1998 Diagn. Microbiol. Infect. Dis. pmid:9554176
Mück W et al. Influence of erythromycin pre- and co-treatment on single-dose pharmacokinetics of the HMG-CoA reductase inhibitor cerivastatin. 1998 Eur. J. Clin. Pharmacol. pmid:9551706
Chakrabarti MK et al. Evaluation of different antibiotics in inhibiting colonization of Vibrio cholerae O1 and O139 in the rabbit intestine. 1998 Mar-Apr Chemotherapy pmid:9551241
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Tanaka E and Breimer DD In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease. 1997 J Clin Pharm Ther pmid:9548204
Bertho G et al. Transferred nuclear Overhauser effect study of macrolide-ribosome interactions: correlation between antibiotic activities and bound conformations. 1998 Bioorg. Med. Chem. pmid:9547944
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Thomas AR et al. Prolongation of the QT interval related to cisapride-diltiazem interaction. 1998 Mar-Apr Pharmacotherapy pmid:9545159
Norcia LJ et al. In vitro microbiological characterization of novel macrolide CP-163,505 for animal health specific use. 1998 J. Antibiot. pmid:9544934
Williamson KM et al. Effects of erythromycin or rifampin on losartan pharmacokinetics in healthy volunteers. 1998 Clin. Pharmacol. Ther. pmid:9542475
Jacobsen JR et al. Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis. 1998 Biochemistry pmid:9538011
Lyon AJ et al. Randomised trial of erythromycin on the development of chronic lung disease in preterm infants. 1998 Arch. Dis. Child. Fetal Neonatal Ed. pmid:9536833
Choi MG et al. Dose-related effects of N-demethyl-N-isopropyl-8, 9-anhydroerythromycin A 6,9-hemiacetal on gastric emptying of solids in healthy human volunteers. 1998 J. Pharmacol. Exp. Ther. pmid:9535992
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Ponomareva TR and Smolianskaia AZ [Prevalence of markers characteristic for penicillinase plasmids in clinical strains of straphylococci]. 1976 Antibiotiki pmid:952503
Roberts GJ et al. Bacteremia of dental origin and antimicrobial sensitivity following oral surgical procedures in children. 1998 Jan-Feb Pediatr Dent pmid:9524970
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Liu PC et al. Susceptibility of different isolates of Vibrio harveyi to antibiotics. 1997 Microbios pmid:9523424
Lester GD et al. Effect of erythromycin lactobionate on myoelectric activity of ileum, cecum, and right ventral colon, and cecal emptying of radiolabeled markers in clinically normal ponies. 1998 Am. J. Vet. Res. pmid:9522953
Esposito S et al. Clinical comparison of cefaclor twice daily versus amoxicillin-clavulanate or erythromycin three times daily in the treatment of patients with streptococcal pharyngitis. 1998 Jan-Feb Clin Ther pmid:9522105
Service RF Hijacking a cell's chemical paths to make new antibiotics. 1997 Science pmid:9518361
Lalloo AK and Kanfer I Determination of erythromycin and related substances by capillary electrophoresis. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9518168
Lalloo AK et al. Development of a capillary electrophoretic method for the separation of the macrolide antibiotics, erythromycin, josamycin and oleandomycin. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9518167
Pankuch GA et al. Susceptibilities of penicillin- and erythromycin-susceptible and -resistant pneumococci to HMR 3647 (RU 66647), a new ketolide, compared with susceptibilities to 17 other agents. 1998 Antimicrob. Agents Chemother. pmid:9517943
Sato K et al. Therapeutic effect of erythromycin on influenza virus-induced lung injury in mice. 1998 Am. J. Respir. Crit. Care Med. pmid:9517602
Lu G et al. Effect of motilin and erythromycin on calcium-activated potassium channels in rabbit colonic myocytes. 1998 Gastroenterology pmid:9516395
Wynn RL Serious erythromycin interactions caused by inhibition of drug metabolism in the liver. 1996 Nov-Dec Gen Dent pmid:9515389
Noguchi N and Katayama J Expression in Pseudomonas aeruginosa of an erythromycin-resistance determinant that encodes the mphA gene for macrolide 2'-phosphotransferase I from Escherichia coli. 1998 Biol. Pharm. Bull. pmid:9514620
Perez-Trallero E et al. Emergence of Streptococcus pyogenes strains resistant to erythromycin in Gipuzkoa, Spain. 1998 Eur. J. Clin. Microbiol. Infect. Dis. pmid:9512178
Jorgensen JH and McElmeel ML Activity of quinupristin/dalfopristin and its components against Haemophilus influenzae. 1997 J. Antimicrob. Chemother. pmid:9511067
Williams JD et al. Comparative in-vitro activity of quinupristin/dalfopristin against Enterococcus spp. 1997 J. Antimicrob. Chemother. pmid:9511061
Manninen R et al. Reliability of disc diffusion susceptibility testing of Streptococcus pneumoniae and adjustment of laboratory-specific breakpoints. Finnish Study Group for Antimicrobial Resistance. 1998 J. Antimicrob. Chemother. pmid:9511033
Hay PE Therapy of bacterial vaginosis. 1998 J. Antimicrob. Chemother. pmid:9511031
Chen JD et al. Effects of octreotide and erythromycin on gastric myoelectrical and motor activities in patients with gastroparesis. 1998 Dig. Dis. Sci. pmid:9508540
Tsiaoussis I et al. Gallbladder fasting volume is reduced and gallbladder postprandial emptying is enhanced by intravenous erythromycin. 1998 Dig. Dis. Sci. pmid:9508522
Rivera P et al. [Collagenous colitis: presentation of 12 cases]. 1997 Gastroenterol Hepatol pmid:9508483
Kamoun A et al. [Pneumococcal infections: penicillin resistance and therapeutic implications]. 1995 Tunis Med pmid:9506153
Wong SL et al. The effect of erythromycin on the CYP3A component of sertindole clearance in healthy volunteers. 1997 J Clin Pharmacol pmid:9505999
Woodward A and Sillin LF Oral erythromycin improves gastrointestinal motility and transit after subtotal but not total gastrectomy for cancer. 1998 Br J Surg pmid:9501836