| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hyperhidrosis | D006945 | 2 associated lipids |
| Jaw Abnormalities | D007569 | 1 associated lipids |
| Skin Diseases, Vascular | D017445 | 1 associated lipids |
| Marfan Syndrome | D008382 | 2 associated lipids |
| Elephantiasis | D004604 | 2 associated lipids |
| Lymphangitis | D008205 | 4 associated lipids |
| Gastric Outlet Obstruction | D017219 | 1 associated lipids |
| Hyperemesis Gravidarum | D006939 | 2 associated lipids |
| Empyema, Pleural | D016724 | 2 associated lipids |
| Lymphoma, B-Cell, Marginal Zone | D018442 | 1 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dimaraki EV and Jaffe CA | Troglitazone induces CYP3A4 activity leading to falsely abnormal dexamethasone suppression test. | 2003 | J. Clin. Endocrinol. Metab. | pmid:12843151 |
| Iuliucci RJ et al. | Ring-chain tautomerism in solid-phase erythromycin A: evidence by solid-state NMR. | 2003 | Solid State Nucl Magn Reson | pmid:12850255 |
| George RC et al. | Antibiotic-resistant pneumococci in the United Kingdom. | 1992 | Commun Dis Rep CDR Rev | pmid:1285099 |
| McGhan LJ and Merchant SN | Erythromycin ototoxicity. | 2003 | Otol. Neurotol. | pmid:12851569 |
| Burkhart CN | Reassessment of combining benzoyl peroxide with clindamycin. | 2002 | J Drugs Dermatol | pmid:12851984 |
| Thiele J et al. | Mixed chimerism of erythro- and megakaryopoiesis following allogeneic bone marrow transplantation. | 2003 | Acta Haematol. | pmid:12853689 |
| Musumeci R et al. | Internalization-associated proteins among Streptococcus pyogenes isolated from asymptomatic carriers and children with pharyngitis. | 2003 | Clin. Infect. Dis. | pmid:12856208 |
| Liu H et al. | Effect of erythromycin on contractile response of uterine smooth muscle strips in non-pregnant rats. | 2003 Jan-Feb | Pol J Pharmacol | pmid:12856827 |
| Bhattacharya MK et al. | Azithromycin in the treatment of cholera in children. | 2003 | Acta Paediatr. | pmid:12856976 |
| Tenson T et al. | The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. | 2003 | J. Mol. Biol. | pmid:12860123 |
| Fisk P | An inguinal bubo caused by Mycobacterium chelonae abscessus. | 1992 Nov-Dec | Int J STD AIDS | pmid:1286124 |
| Schöni MH | Macrolide antibiotic therapy in patients with cystic fibrosis. | 2003 | Swiss Med Wkly | pmid:12861467 |
| Frean J et al. | Susceptibility of Bacillus anthracis to eleven antimicrobial agents including novel fluoroquinolones and a ketolide. | 2003 | J. Antimicrob. Chemother. | pmid:12865385 |
| Mirza S et al. | Influence of solvents on the variety of crystalline forms of erythromycin. | 2003 | AAPS PharmSci | pmid:12866939 |
| Deshpande LM and Jones RN | Antagonism between penicillin and erythromycin against Streptococcus pneumoniae: does it exist? | 2003 | Diagn. Microbiol. Infect. Dis. | pmid:12867099 |
| Corrêa JC et al. | Randomized, open-label, parallel-group, multicenter study of the efficacy and tolerability of IV gatifloxacin with the option for oral stepdown gatifloxacin versus IV ceftriaxone (with or without erythromycin or clarithromycin) with the option for oral stepdown clarithromycin for treatment of patients with mild to moderate community-acquired pneumonia requiring hospitalization. | 2003 | Clin Ther | pmid:12867221 |
| Wolf R et al. | Sulfonamide-induced bullous hemorrhagic eruption in a patient with low prothrombin time. | 1992 | Isr. J. Med. Sci. | pmid:1286961 |
| Hergenrother PJ et al. | An abiotic strategy for the enantioselective synthesis of erythromycin B. | 2003 | Angew. Chem. Int. Ed. Engl. | pmid:12876743 |
| Vanden Boom TJ | Recent developments in the molecular genetics of the erythromycin-producing organism Saccharopolyspora erythraea. | 2000 | Adv. Appl. Microbiol. | pmid:12876795 |
| Syrogiannopoulos GA et al. | Antimicrobial susceptibility and macrolide resistance inducibility of Streptococcus pneumoniae carrying erm(A), erm(B), or mef(A). | 2003 | Antimicrob. Agents Chemother. | pmid:12878546 |
| Pai SR et al. | In vivo efficacy of the ketolide ABT-773 (cethromycin) against enterococci in a mouse peritonitis model. | 2003 | Antimicrob. Agents Chemother. | pmid:12878548 |
| Crum NF et al. | Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. | 2003 | Am J Prev Med | pmid:12880877 |
| Schmidt LE et al. | Relationship between postoperative erythromycin breath test and early morbidity in liver transplant recipients. | 2003 | Transplantation | pmid:12883193 |
| Peck KR et al. | Antimicrobials as potential adjunctive agents in the treatment of biofilm infection with Staphylococcus epidermidis. | 2003 | Chemotherapy | pmid:12886054 |
| Portillo A et al. | Clonal diversity among erythromycin-resistant beta-haemolytic Streptococcus isolates in La Rioja, Spain. | 2003 | J. Antimicrob. Chemother. | pmid:12888595 |
| Shishkov N and Drumev D | [Possible synergic action of some drug combinations against Mycoplasma gallisepticum]. | 1975 | Vet Med Nauki | pmid:128891 |
| Mercer BM et al. | What we have learned regarding antibiotic therapy for the reduction of infant morbidity after preterm premature rupture of the membranes. | 2003 | Semin. Perinatol. | pmid:12889589 |
| Andrews WW and Goldenberg RL | What we have learned from an antibiotic trial in fetal fibronectin positive women. | 2003 | Semin. Perinatol. | pmid:12889590 |
| Fietta A et al. | Uptake of flurithromycin by human polymorphonuclear phagocytes: partial characterization of the entry mechanism. | 1992 | Chemotherapy | pmid:1288969 |
| Haefeli WE et al. | Possible risk for cardiac arrhythmia related to intravenous erythromycin. | 1992 | Intensive Care Med | pmid:1289371 |
| Murli S et al. | Metabolic engineering of Escherichia coli for improved 6-deoxyerythronolide B production. | 2003 | J. Ind. Microbiol. Biotechnol. | pmid:12898389 |
| Schlüsener MP et al. | Determination of antibiotics from soil by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry. | 2003 | J Chromatogr A | pmid:12899294 |
| Yongge L et al. | Relationship between plasma motilin and effect of oral erythromycin on gallbladder contraction in patients of functional dyspepsia. | 2000 | Chin. Med. Sci. J. | pmid:12901646 |
| Huang JQ and Xie CM | [The effects of erythromycin on the secretion of tumor necrosis factor-alpha and transforming growth factor-beta1 and expression of connexin 43 in human pleural mesothelial cells]. | 2003 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:12901826 |
| Kuijper EJ et al. | Genotypic identification of erythromycin-resistant campylobacter isolates as helicobacter species and analysis of resistance mechanism. | 2003 | J. Clin. Microbiol. | pmid:12904383 |
| Hu Z et al. | A specific role of the Saccharopolyspora erythraea thioesterase II gene in the function of modular polyketide synthases. | 2003 | Microbiology (Reading, Engl.) | pmid:12904561 |
| Hankø E et al. | Administration of drugs known to inhibit P-glycoprotein increases brain bilirubin and alters the regional distribution of bilirubin in rat brain. | 2003 | Pediatr. Res. | pmid:12904601 |
| Stratchounski LS et al. | The inventory of antibiotics in Russian home medicine cabinets. | 2003 | Clin. Infect. Dis. | pmid:12905133 |
| Hanada E et al. | Inhibitory effect of erythromycin on potassium currents in rat ventricular myocytes in comparison with disopyramide. | 2003 | J. Pharm. Pharmacol. | pmid:12906757 |
| Pearlman M | Prevention of early-onset group B streptococcal disease in newborns. | 2003 | Obstet Gynecol | pmid:12907122 |
| Maravić G et al. | Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions. | 2003 | Nucleic Acids Res. | pmid:12907737 |
| Lemahieu WP et al. | Measurement of hepatic and intestinal CYP3A4 and PGP activity by combined po + iv [14C]erythromycin breath and urine test. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12909563 |
| Carletti M et al. | In vitro formation of metabolic-intermediate cytochrome P450 complexes in rabbit liver microsomes by tiamulin and various macrolides. | 2003 Jul-Aug | Vet. Res. | pmid:12911857 |
| Tack J et al. | Assessment of meal induced gastric accommodation by a satiety drinking test in health and in severe functional dyspepsia. | 2003 | Gut | pmid:12912857 |
| Reina J et al. | Emergence of resistance to erythromycin and fluoroquinolones in thermotolerant Campylobacter strains isolated from feces 1987-1991. | 1992 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:1291314 |
| Miyashita N et al. | In vitro activity of cethromycin, a novel antibacterial ketolide, against Chlamydia pneumoniae. | 2003 | J. Antimicrob. Chemother. | pmid:12917246 |
| Walsh F et al. | High-level telithromycin resistance in laboratory-generated mutants of Streptococcus pneumoniae. | 2003 | J. Antimicrob. Chemother. | pmid:12917252 |
| Weber K | How I treat perioral dermatitis: non-compliance with the treatment guidelines. | 2003 | Dermatology (Basel) | pmid:12920383 |
| Cleary JD et al. | Effects of amphotericin B and caspofungin on histamine expression. | 2003 | Pharmacotherapy | pmid:12921242 |
| Ioannidou S et al. | In vitro activity of telithromycin (HMR 3647) against Greek Streptococcus pyogenes and Streptococcus pneumoniae clinical isolates with different macrolide susceptibilities. | 2003 | Clin. Microbiol. Infect. | pmid:12925112 |
| Enomoto F et al. | Modulation of neutrophil adhesion to vascular endothelial cells in rat experimental otitis media treated with a macrolide. | 2003 | Auris Nasus Larynx | pmid:12927286 |
| Ergin A et al. | In vitro susceptibility, tolerance and MLS resistance phenotypes of Group C and Group G streptococci isolated in Turkey between 1995 and 2002. | 2003 | Int. J. Antimicrob. Agents | pmid:12927957 |
| Blandino G et al. | Bactericidal activity and postantibiotic effect of cefdinir (Cl 983, FK 482) against selected pathogens. | 1992 | Drugs Exp Clin Res | pmid:1292914 |
| Metaxa-Mariatou V et al. | Documentation of Legionella pneumophila and Mycobacterium tuberculosis co-existence in a patient with acute respiratory distress syndrome. | 2003 Jul-Aug | In Vivo | pmid:12929592 |
| Bowers AK et al. | Molecular markers for rapidly identifying candidate genes in Chlamydomonas reinhardtii. Ery1 and ery2 encode chloroplast ribosomal proteins. | 2003 | Genetics | pmid:12930744 |
| Ponte C et al. | Does acetaminophen interfere in the antibiotic treatment of acute otitis media caused by a penicillin-resistant pneumococcus strain? A gerbil model. | 2003 | Pediatr. Res. | pmid:12930908 |
| Petkovic H et al. | A novel erythromycin, 6-desmethyl erythromycin D, made by substituting an acyltransferase domain of the erythromycin polyketide synthase. | 2003 | J. Antibiot. | pmid:12931864 |
| Mikasa K et al. | [The 5th report on long-term chemotherapy using erythromycin (EM) for chronic lower airway infection--cases followed over 7 years]. | 1992 | Kansenshogaku Zasshi | pmid:1293219 |
| Cao W et al. | [Infectious distribution and resistant of Neisseria gonorrhoeae, Mycoplasma, and Chlamydia trachomatis in the chronic prostatitis]. | 2003 | Hunan Yi Ke Da Xue Xue Bao | pmid:12934372 |
| Giovanetti E et al. | Presence of the tet(O) gene in erythromycin- and tetracycline-resistant strains of Streptococcus pyogenes and linkage with either the mef(A) or the erm(A) gene. | 2003 | Antimicrob. Agents Chemother. | pmid:12936983 |
| George A and Rubin G | A systematic review and meta-analysis of treatments for impetigo. | 2003 | Br J Gen Pract | pmid:12939895 |
| Okubo T et al. | [Antimicrobial activities of macrolides against recent clinical isolates, and analysis of resistant mechanisms]. | 2003 | Jpn J Antibiot | pmid:12942787 |
| Sekiguchi J et al. | Spread of erythromycin-, tetracycline-, and aminoglycoside-resistant genes in methicillin-resistant Staphylococcus aureus clinical isolates in a Kumamoto Hospital. | 2003 | Jpn. J. Infect. Dis. | pmid:12944686 |
| Li F et al. | [An experimental study of gastric pacing on postsurgical gastric dynamic dysfunction]. | 2003 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:12947728 |
| Sharp JS and Bechhofer DH | Effect of translational signals on mRNA decay in Bacillus subtilis. | 2003 | J. Bacteriol. | pmid:12949089 |
| Veronese ML et al. | Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice. | 2003 | J Clin Pharmacol | pmid:12953340 |
| Janssen LJ and Wattie J | Electrophysiological effects of erythromycin, but lack of mechanical effects, in airway smooth muscle. | 2003 | Eur. J. Pharmacol. | pmid:12954364 |
| Dehouck P et al. | Analysis of erythromycin and benzoylperoxide in topical gels by liquid chromatography. | 2003 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:12954380 |
| Baier RJ et al. | Failure of erythromycin to eliminate airway colonization with ureaplasma urealyticum in very low birth weight infants. | 2003 | BMC Pediatr | pmid:12956892 |
| Zhang L et al. | P-glycoprotein restricted transport of nimodipine across blood-brain barrier. | 2003 | Acta Pharmacol. Sin. | pmid:12956939 |
| Baquero F and Reig M | Resistance of anaerobic bacteria to antimicrobial agents in Spain. | 1992 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:1295754 |
| Qin XY et al. | Involvement of dopamine D3 and neuropeptide Y Y5 receptors in diabetic gastroparetic rats without response to erythromycin. | 2003 | Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao | pmid:12958653 |
| ElHennawy AA et al. | Erythromycin fails to improve feeding outcome in feeding-intolerant preterm infants. | 2003 | J. Pediatr. Gastroenterol. Nutr. | pmid:12960650 |
| Cook MA et al. | Uptake of erythromycin by first-feeding sockeye salmon, Oncorhynchus nerka (Walbaum), fed live or freeze-dried enriched adult Artemia or medicated pellets. | 2003 | J. Fish Dis. | pmid:12962236 |
| Oriabinskaia LB et al. | [Energy metabolism in Staphylococci containing plasmids of resistance to a number of antibiotics]. | 1992 | Antibiot. Khimioter. | pmid:1296533 |
| Grigor'ev AE et al. | [Construction of hybrid plasmids containing genes for erythromycin biosynthesis and amplifying sequence AUD-Sr1 of Streptomyces rimosus]. | 1992 | Antibiot. Khimioter. | pmid:1296539 |
| Alvarado A and Flores ME | Characterization and regulation of NADP+-isocitrate dehydrogenase from Saccharopolyspora erythraea. | 2003 | Biotechnol. Lett. | pmid:12967008 |
| Boivin M et al. | Motilin and the postprandial motility of the antrum. | 1992 | Can. J. Physiol. Pharmacol. | pmid:1296862 |
| Solladié-Cavallo A et al. | erythro-1-Naphthyl-1-(2-piperidyl)methanol: synthesis, resolution, NMR relative configuration, and VCD absolute configuration. | 2003 | J. Org. Chem. | pmid:12968880 |
| Volokhov D et al. | Microarray analysis of erythromycin resistance determinants. | 2003 | J. Appl. Microbiol. | pmid:12969293 |
| Sugihara E et al. | Macrolide antibiotics directly reduce active oxygen generation by neutrophils in human peripheral blood. | 2003 | Kurume Med J | pmid:12971257 |
| Hoogmartens J | Liquid chromatography for the quantitative analysis of antibiotics--some applications using poly(styrene-divinylbenzene). | 1992 Oct-Dec | J Pharm Biomed Anal | pmid:1298392 |
| ERYTHROMYCIN. | 1952 | Br Med J | pmid:12987755 | |
| ANDERSON RC et al. | The toxicity and distribution of ilotycin. | 1952 | J Am Pharm Assoc Am Pharm Assoc | pmid:12999613 |
| Bavoux F | [Torsades de pointes and anti-infective agents]. | 1992 Sep-Oct | Therapie | pmid:1299973 |
| Petrova MS et al. | [Antibiotic therapy in children with pertussis]. | 1992 | Antibiot. Khimioter. | pmid:1300936 |
| Shi XZ and Zhang JJ | [Erythromycin: a motilin receptor agonist]. | 1992 | Sheng Li Ke Xue Jin Zhan | pmid:1302371 |
| Lum L and Ngeow YF | Chlamydia pneumoniae respiratory infection in a child--a case report. | 1992 | Med. J. Malaysia | pmid:1303485 |
| DEARING WH | Micrococcic (staphylococcic) enteritis as a complication of antibiotic therapy; its response to erythromycin. | 1953 | Proc Staff Meet Mayo Clin | pmid:13037897 |
| Song JF et al. | [Resistant rate to antibiotics in Tian Tan Hospital for 3 years]. | 1992 | Zhonghua Nei Ke Za Zhi | pmid:1303851 |
| NEW antibiotic. | 1953 | South. Med. J. | pmid:13038549 | |
| Leelarasamee A and Leelarasamee I | Comparative efficacy of spiramycin and erythromycin in acute exudative tonsillitis in adults: a randomized controlled trial. | 1992 | J Med Assoc Thai | pmid:1304021 |
| MCCOWEN MC et al. | The effects of erythromycin (ilotycin, lilly) against certain parasitic organisms. | 1953 | Am. J. Trop. Med. Hyg. | pmid:13040654 |
| HAIGHT TH and FINLAND M | The antibacterial action of erythromycin. | 1952 | Proc. Soc. Exp. Biol. Med. | pmid:13047351 |
| FREEMAN LC and SCOTT RB | Erythromycin in treatment of pyoderma in children. | 1953 | J. Pediatr. | pmid:13053367 |
| VANNUCCHI V | [Clinical study of a new antibiotic; erythromycin]. | 1952 | Riv Crit Clin Med | pmid:13056483 |
| NESERKE EI | Clinical report on the new antibiotic, erythromycin. | 1953 | J. Am. Vet. Med. Assoc. | pmid:13061363 |
| Ramirez JA et al. | Bactericidal activity of imipenem compared to erythromycin against intracellular Legionella pneumophila. | 1992 | Drugs Exp Clin Res | pmid:1306151 |
| Wang BF | [A clinical study of 50 cases of Legionnaires disease]. | 1992 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:1306405 |
| GABLE GR et al. | Treatment of gonorrhea with erythromycin. | 1953 | Am J Syph Gonorrhea Vener Dis | pmid:13065617 |