erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hyperhidrosis D006945 2 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Marfan Syndrome D008382 2 associated lipids
Elephantiasis D004604 2 associated lipids
Lymphangitis D008205 4 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Hyperemesis Gravidarum D006939 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Kumpfmüller J et al. Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis. 2016 Appl. Microbiol. Biotechnol. pmid:26432460
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Aslantaş Ö and Demir C Investigation of the antibiotic resistance and biofilm-forming ability of Staphylococcus aureus from subclinical bovine mastitis cases. 2016 J. Dairy Sci. pmid:27592437
Budha NR et al. Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation. 2016 Clin Pharmacokinet pmid:27225997
Wan TW et al. Complete Circular Genome Sequence of Successful ST8/SCCmecIV Community-Associated Methicillin-Resistant Staphylococcus aureus (OC8) in Russia: One-Megabase Genomic Inversion, IS256's Spread, and Evolution of Russia ST8-IV. 2016 PLoS ONE pmid:27741255
Hadjipanayis A et al. Nasopharyngeal Pneumococcal Carriage among Healthy Children in Cyprus Post Widespread Simultaneous Implementation of PCV10 and PCV13 Vaccines. 2016 PLoS ONE pmid:27706247
Krishnamoorthy G et al. Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane. 2016 Antimicrob. Agents Chemother. pmid:27697764
Kwon JW Environmental impact assessment of veterinary drug on fish aquaculture for food safety. 2016 Drug Test Anal pmid:27443211
Aslan Bayhan S et al. Effects of topical acne treatment on the ocular surface in patients with acne vulgaris. 2016 Cont Lens Anterior Eye pmid:27422575
Li X et al. Effects of Total Alkaloids of Sophora alopecuroides on Biofilm Formation in Staphylococcus epidermidis. 2016 Biomed Res Int pmid:27413745
Ababou A and Koronakis V Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. 2016 PLoS ONE pmid:27403665
Yuan QB et al. Reductions of bacterial antibiotic resistance through five biological treatment processes treated municipal wastewater. 2016 Environ Sci Pollut Res Int pmid:27384166
Karlsson E et al. Clonality of erythromycin resistance in Francisella tularensis. 2016 J. Antimicrob. Chemother. pmid:27334667
Changchien CH et al. Antibiotic susceptibility and genomic variations in Staphylococcus aureus associated with Skin and Soft Tissue Infection (SSTI) disease groups. 2016 BMC Infect. Dis. pmid:27287530
Mukai S et al. Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. 2016 Int. J. Oncol. pmid:26718641
Sousa M et al. Genetic Diversity and Antibiotic Resistance Among Coagulase-Negative Staphylococci Recovered from Birds of Prey in Portugal. 2016 Microb. Drug Resist. pmid:26990729
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Sierra-Arguello YM et al. Fluoroquinolone and macrolide resistance in Campylobacter jejuni isolated from broiler slaughterhouses in southern Brazil. 2016 Avian Pathol. pmid:26925976
Molina-Manso D et al. Effect of different agents with potential antibiofilm activity on antimicrobial susceptibility of biofilms formed by Staphylococcus spp. isolated from implant-related infections. 2016 J. Antibiot. pmid:26905757
Meng HL et al. Construction of polyketide overproducing Escherichia coli strains via synthetic antisense RNAs based on in silico fluxome analysis and comparative transcriptome analysis. 2016 Biotechnol J pmid:26709503
Madmanang S et al. Constituents of Fagraea fragrans with Antimycobacterial Activity in Combination with Erythromycin. 2016 J. Nat. Prod. pmid:26905094
Dréno B Bacteriological resistance in acne: A call to action. 2016 Eur J Dermatol pmid:26711531
Parhizgari N et al. High frequency of multidrug-resistant Staphylococcus aureus with SCCmec type III and Spa types t037 and t631 isolated from burn patients in southwest of Iran. 2016 APMIS pmid:26709106
Chuang MC et al. Diffuse panbronchiolitis-The response and recurrence after erythromycin therapy. 2016 J. Formos. Med. Assoc. pmid:26705139
Li J et al. Rhubarb to Facilitate Placement of Nasojejunal Feeding Tubes in Patients in the Intensive Care Unit. 2016 Nutr Clin Pract pmid:26459161
Shimizu T and Suzaki H Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. 2016 Auris Nasus Larynx pmid:26441370
Feuillolay C et al. A Myrtus communis extract enriched in myrtucummulones and ursolic acid reduces resistance of Propionibacterium acnes biofilms to antibiotics used in acne vulgaris. 2016 Phytomedicine pmid:26969384
Zankari E et al. PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens. 2017 J. Antimicrob. Chemother. pmid:29091202
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Hodge S et al. Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28258107
Lee JH et al. Genetic Diversity and Antibiotic Resistance of Enterococcus faecalis Isolates from Traditional Korean Fermented Soybean Foods. 2017 J. Microbiol. Biotechnol. pmid:28237994
Sugimoto N et al. Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. 2017 BMC Res Notes pmid:28057059
Liu J et al. Modulation of erythromycin-induced biochemical responses in crucian carp by ketoconazole. 2017 Environ Sci Pollut Res Int pmid:28004371
Hillitt KL et al. Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum. 2017 Lett. Appl. Microbiol. pmid:27992658
Pavlović D et al. Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. 2017 Eur J Med Chem pmid:27657812
Ricker EB and Nuxoll E Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. 2017 Biofouling pmid:29039211
Bitew A et al. Species distribution and antibiotic susceptibility profile of bacterial uropathogens among patients complaining urinary tract infections. 2017 BMC Infect. Dis. pmid:28962545
Öksüz L and Gürler N [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital]. 2017 Mikrobiyol Bul pmid:28929957
Pan M and Chu LM Transfer of antibiotics from wastewater or animal manure to soil and edible crops. 2017 Environ. Pollut. pmid:28866424
Wekselman I et al. The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. 2017 Structure pmid:28689968
Truong-Bolduc QC et al. Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump. 2017 Antimicrob. Agents Chemother. pmid:28584148
Atkinson CT et al. Expression of acquired macrolide resistance genes in Haemophilus influenzae. 2017 J. Antimicrob. Chemother. pmid:28961896
Zhou Z et al. Combination of Erythromycin and Curcumin Alleviates Induced Osteomyelitis in Rats. 2017 Front Cell Infect Microbiol pmid:28884090
Quinn KL et al. Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. 2017 Drug Saf pmid:28421551
Zhao L et al. Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. 2017 J Sep Sci pmid:28121061
Dreno B et al. Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. 2017 Exp. Dermatol. pmid:28094874