erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diarrhea D003967 32 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Uremia D014511 33 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Acne Vulgaris D000152 35 associated lipids
Glomerulonephritis D005921 35 associated lipids
Epilepsy D004827 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Gaudreau C et al. Long-Lasting Outbreak of Erythromycin- and Ciprofloxacin-Resistant Campylobacter jejuni Subspecies jejuni From 2003 to 2013 in Men Who Have Sex With Men, Quebec, Canada. 2015 Clin. Infect. Dis. pmid:26187024
Dayie NT et al. Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children. 2015 Microb. Drug Resist. pmid:26172078
He M et al. Dynamics of serotype 14 Streptococcus pneumoniae population causing acute respiratory infections among children in China (1997-2012). 2015 BMC Infect. Dis. pmid:26163293
Piccinelli G et al. Characterization and antibiotic susceptibility of Streptococcus agalactiae isolates causing urinary tract infections. 2015 Infect. Genet. Evol. pmid:26144658
Kasai A et al. Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. 2015 J. Med. Microbiol. pmid:25934551
Melkumyan AR et al. Effects of antibiotic treatment on the lactobacillus composition of vaginal microbiota. 2015 Bull. Exp. Biol. Med. pmid:25894774
Romaniszyn D et al. Epidemiology, antibiotic consumption and molecular characterisation of Staphylococcus aureus infections--data from the Polish Neonatology Surveillance Network, 2009-2012. 2015 BMC Infect. Dis. pmid:25888217
Park JY et al. Construction of a shuttle vector based on the small cryptic plasmid pJY33 from Weissella cibaria 33. 2015 Plasmid pmid:25882072
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Shi JG et al. Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib. 2015 Clin. Pharmacol. Ther. pmid:25670523
Xu CW et al. First report of macrolide resistance gene erm(T) harbored by a novel small plasmid from Erysipelothrix rhusiopathiae. 2015 Antimicrob. Agents Chemother. pmid:25666150
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García-Mayor MA et al. Occurrence of erythromycin residues in sheep milk. Validation of an analytical method. 2015 Food Chem. Toxicol. pmid:25637760
Chan BC et al. Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. 2015 J. Pharm. Pharmacol. pmid:25212982
Shishkina AV et al. Modeling Interactions of Erythromycin Derivatives with Ribosomes. 2015 Biochemistry Mosc. pmid:26615442
Li X et al. Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility. 2015 Sci Rep pmid:26607739
Kojima C et al. Distribution of Antimicrobial Resistance in Campylobacter Strains Isolated from Poultry at a Slaughterhouse and Supermarkets in Japan. 2015 Biocontrol Sci pmid:26412697
Yang Y et al. Variation in Bordetella pertussis Susceptibility to Erythromycin and Virulence-Related Genotype Changes in China (1970-2014). 2015 PLoS ONE pmid:26406905
O'Connor SE Engineering of Secondary Metabolism. 2015 Annu. Rev. Genet. pmid:26393965
Borges V et al. Helicobacter pullorum isolated from fresh chicken meat: antibiotic resistance and genomic traits of an emerging foodborne pathogen. 2015 Appl. Environ. Microbiol. pmid:26386065
Dixit S and Park JH Enantioseparation of basic chiral drugs on a carbamoylated erythromycin-zirconia hybrid monolith using capillary electrochromatography. 2015 J Chromatogr A pmid:26372443
Ozbayram EG et al. Acute effects of various antibiotic combinations on acetoclastic methanogenic activity. 2015 Environ Sci Pollut Res Int pmid:25408075
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Nikolay R et al. Validation of a fluorescence-based screening concept to identify ribosome assembly defects in Escherichia coli. 2014 Nucleic Acids Res. pmid:24792169
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Pierson RC et al. A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. 2014 Obstet Gynecol pmid:25162251
Rozov-Ung I et al. Detection of drug effects on gastric emptying and contractility using a wireless motility capsule. 2014 BMC Gastroenterol pmid:24383478
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Sugamata R et al. Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. 2014 J. Antibiot. pmid:24496145
Pasquini L et al. Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. 2014 Sci. Total Environ. pmid:24631609
Wu H et al. Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea. 2014 Microb. Cell Fact. pmid:25391994
Caierão J et al. Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. 2014 PLoS ONE pmid:25356595
Usui M et al. Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. 2014 Vet. Rec. pmid:25163817
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Abarzúa F et al. [Prevalence of anal-vaginal colonization of Streptococcus agalactiae in third trimester of pregnancy and susceptibility to macrolides and lincosamides, in pregnant women controlled at Clínica Alemana Temuco, Southern Chile]. 2014 Rev Chilena Infectol pmid:25146205
Carls A et al. Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. 2014 Br J Clin Pharmacol pmid:25139487
Piccinelli G et al. In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. 2014 Antimicrob. Agents Chemother. pmid:24379197
Ramos FL and Criner GJ Use of long-term macrolide therapy in chronic obstructive pulmonary disease. 2014 Curr Opin Pulm Med pmid:24378875
Johansson M et al. Sequence-dependent elongation dynamics on macrolide-bound ribosomes. 2014 Cell Rep pmid:24836000
Jing YR et al. The synthesis of novel taxoids for oral administration. 2014 Bioorg. Med. Chem. pmid:24332858
Borbón-Esquer EM et al. SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. 2014 Scand. J. Infect. Dis. pmid:24832853
Dechert-Schmitt AM et al. Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. 2014 Nat Prod Rep pmid:24514754
Montes M et al. What causes decreased erythromycin resistance in Streptococcus pyogenes? Dynamics of four clones in a southern European region from 2005 to 2012. 2014 J. Antimicrob. Chemother. pmid:24562616
Benito D et al. Genetic lineages, antimicrobial resistance, and virulence in Staphylococcus aureus of meat samples in Spain: analysis of immune evasion cluster (IEC) genes. 2014 Foodborne Pathog. Dis. pmid:24479575
Boomkamp SD et al. Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. 2014 Br. J. Pharmacol. pmid:24467222
Jun BY et al. Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. 2014 Surg Endosc pmid:24380989
Ren WP et al. Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. 2014 J. Biomed. Mater. Res. Part B Appl. Biomater. pmid:24347324