erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diarrhea D003967 32 associated lipids
Uremia D014511 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Epilepsy D004827 35 associated lipids
Fever D005334 35 associated lipids
Acne Vulgaris D000152 35 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Salimi A et al. Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. 2016 Xenobiotica pmid:26068526
Tack J et al. Motilin-induced gastric contractions signal hunger in man. 2016 Gut pmid:25539673
Zmantar T et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. 2016 Microb. Pathog. pmid:27816681
Barbanti F and Spigaglia P Characterization of Clostridium difficile PCR-ribotype 018: A problematic emerging type. 2016 Anaerobe pmid:27725230
Mayor-Ibarguren A et al. Periorificial Lesions in a Young Girl. 2016 Actas Dermosifiliogr pmid:26935746
Hu P et al. Erythromycin triggers intussusception in a pediatric patient with Henoch-Schönlein purpura. 2016 Turk J Gastroenterol pmid:27782898
Heß S and Gallert C Growth Behavior of E. coli, Enterococcus and Staphylococcus Species in the Presence and Absence of Sub-inhibitory Antibiotic Concentrations: Consequences for Interpretation of Culture-Based Data. 2016 Microb. Ecol. pmid:27220972
de Jesus Gaffney V et al. Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. 2016 Environ. Toxicol. Chem. pmid:27061931
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DeLorenzo ME et al. Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. 2016 Environ. Toxicol. pmid:25348372
Xu JY et al. Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. 2016 J. Proteome Res. pmid:27090497
Choe YJ et al. Emergence of antibiotic-resistant non-vaccine serotype pneumococci in nasopharyngeal carriage in children after the use of extended-valency pneumococcal conjugate vaccines in Korea. 2016 Vaccine pmid:27546875
Kang CH et al. Antimicrobial susceptibility of Vibrio alginolyticus isolated from oyster in Korea. 2016 Environ Sci Pollut Res Int pmid:27543129
Metcalf BJ et al. Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States. 2016 Clin. Microbiol. Infect. pmid:27542334
Parasrampuria DA et al. Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. 2016 Br J Clin Pharmacol pmid:27530188
Hua CZ et al. [An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015: a multi-center retrospective study]. 2016 Zhonghua Er Ke Za Zhi pmid:27510868
Johanesen P and Lyras D Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile. 2016 Methods Mol. Biol. pmid:27507343
Barbanti F et al. Transfer of Clostridium difficile Genetic Elements Conferring Resistance to Macrolide-Lincosamide-Streptogramin B (MLSB) Antibiotics. 2016 Methods Mol. Biol. pmid:27507342
Gaglio R et al. Evaluation of antimicrobial resistance and virulence of enterococci from equipment surfaces, raw materials, and traditional cheeses. 2016 Int. J. Food Microbiol. pmid:27467501
Burr LD et al. Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. 2016 Ann Am Thorac Soc pmid:27464029
Tan C et al. Effects of Low-Dose and Long-Term Treatment with Erythromycin on Interleukin-17 and Interleukin-23 in Peripheral Blood and Induced Sputum in Patients with Stable Chronic Obstructive Pulmonary Disease. 2016 Mediators Inflamm. pmid:27127346
Zheng Z et al. Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. 2016 J. Antibiot. pmid:27118243
Mikhail M et al. Orbital cellulitis and multiple abscess formation after strabismus surgery. 2016 Can. J. Ophthalmol. pmid:27085279
Chen Y et al. TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. 2016 Carbohydr Polym pmid:27083368
Del Grosso M et al. ICESpy009, a Conjugative Genetic Element Carrying mef(E) in Streptococcus pyogenes. 2016 Antimicrob. Agents Chemother. pmid:27067338
Aydin S Enhanced biodegradation of antibiotic combinations via the sequential treatment of the sludge resulting from pharmaceutical wastewater treatment using white-rot fungi Trametes versicolor and Bjerkandera adusta. 2016 Appl. Microbiol. Biotechnol. pmid:27033714
Shi HY et al. [Effect of quorum sensing system on the infection of MRSA and the intervention of erythromycin on it]. 2016 Zhonghua Yi Xue Za Zhi pmid:27760665
Hsieh PF et al. The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. 2016 Virulence pmid:27029012
Lewis K et al. The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials. 2016 Crit Care pmid:27527069
Pierattini EC et al. Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. 2016 Sci. Total Environ. pmid:27366984
He HJ et al. Erythromycin resistance features and biofilm formation affected by subinhibitory erythromycin in clinical isolates of Staphylococcus epidermidis. 2016 J Microbiol Immunol Infect pmid:24768213
Katayama Y et al. Neuroprotective effects of erythromycin on ischemic injury following permanent focal cerebral ischemia in rats. 2016 Neurol. Res. pmid:27078702
Argyropoulos P et al. Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. 2016 Biochim. Biophys. Acta pmid:26592346
Liu X et al. Proteomic response of methicillin-resistant S. aureus to a synergistic antibacterial drug combination: a novel erythromycin derivative and oxacillin. 2016 Sci Rep pmid:26806358
Prabhasankar VP et al. Removal rates of antibiotics in four sewage treatment plants in South India. 2016 Environ Sci Pollut Res Int pmid:26797959
Seefeldt AC et al. Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. 2016 Nucleic Acids Res. pmid:26792896
Li M et al. Sugar-Grafted Cyclodextrin Nanocarrier as a "Trojan Horse" for Potentiating Antibiotic Activity. 2016 Pharm. Res. pmid:26792570
Lapierre L et al. Characterization of Antimicrobial Susceptibility and Its Association with Virulence Genes Related to Adherence, Invasion, and Cytotoxicity in Campylobacter jejuni and Campylobacter coli Isolates from Animals, Meat, and Humans. 2016 Microb. Drug Resist. pmid:26779841
Pan M and Chu LM Phytotoxicity of veterinary antibiotics to seed germination and root elongation of crops. 2016 Ecotoxicol. Environ. Saf. pmid:26773832
Rodrigues S et al. Acute and chronic effects of erythromycin exposure on oxidative stress and genotoxicity parameters of Oncorhynchus mykiss. 2016 Sci. Total Environ. pmid:26760278
Cheng Y et al. Comparative study between macrolide regulatory proteins MphR(A) and MphR(E) in ligand identification and DNA binding based on the rapid in vitro detection system. 2016 Anal Bioanal Chem pmid:26753969
Maye S et al. Transformation of serum-susceptible Escherichia coli O111 with p16Slux plasmid to allow for real-time monitoring of complement-based inactivation of bacterial growth in bovine milk. 2016 J. Dairy Sci. pmid:26585477
Nenquin M and Henquin JC Sulphonylurea receptor-1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells. 2016 Diabetes Obes Metab pmid:26584950
Arenz S et al. A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. 2016 Nat Commun pmid:27380950
Wu H et al. In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea. 2016 Appl. Microbiol. Biotechnol. pmid:26552796
Berg L et al. [Cutaneous diphtheria after a minor injury in Sri Lanka]. 2016 Hautarzt pmid:26525966
Takahashi T et al. Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. 2016 Ann Lab Med pmid:26522753
Boetsch C et al. Effects of Cytochrome P450 3A4 Inhibitors-Ketoconazole and Erythromycin-on Bitopertin Pharmacokinetics and Comparison with Physiologically Based Modelling Predictions. 2016 Clin Pharmacokinet pmid:26341813
Giuliano MW and Miller SJ Site-Selective Reactions with Peptide-Based Catalysts. 2016 Top Curr Chem pmid:26307403
Snoeys J et al. Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. 2016 Clin. Pharmacol. Ther. pmid:26259716