erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Yuan H et al. [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. 2011 Zhonghua Jie He He Hu Xi Za Zhi pmid:22041779
Fan L and Xu J [Application progress of macrolide sustained therapy for bronchiectasis]. 2014 Zhonghua Jie He He Hu Xi Za Zhi pmid:24694975
Yu L and Ran PX [Effects of erythromycin on the synthesis of interleukin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells]. 2009 Zhonghua Jie He He Hu Xi Za Zhi pmid:19567187
Xiao W et al. [The imbalance of Th1/Th2 cytokine expression in peripheral blood mononuclear cell from asthmatic patients and the effect of erythromycin on these cytokines]. 2000 Zhonghua Jie He He Hu Xi Za Zhi pmid:11778516
Gu XH et al. [Effects of erythromycin on the twitching motility of Pseudomonas aeruginosa]. 2007 Zhonghua Jie He He Hu Xi Za Zhi pmid:17573001
Zhong XN and Guo SM [An experimental study on pulmonary vascular inflammation in a rat model of chronic bronchitis and emphysema]. 2006 Zhonghua Jie He He Hu Xi Za Zhi pmid:17045040
Liu J et al. [mRNA expression of basic fibroblast growth factor in the pulmonary tissues from rats repeatedly infected with mycoplasma pneumoniae]. 1999 Zhonghua Jie He He Hu Xi Za Zhi pmid:11775917
Li Y et al. [The effect of erythromycin on NF-kappa B activation and cytokines mRNA expression in bleomycin-induced pulmonary fibrosis in rats]. 1999 Zhonghua Jie He He Hu Xi Za Zhi pmid:11776779
Tang YC [Diagnosis and treatment of Legionnaires' disease from opportunistic infection]. 1987 Zhonghua Jie He He Hu Xi Za Zhi pmid:3440298
Lu W et al. [Analysis of 37 cases of pneumonia of Legionnaires' disease]. 1997 Zhonghua Jie He He Hu Xi Za Zhi pmid:10072832