erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hypersensitivity, Delayed D006968 43 associated lipids
Psoriasis D011565 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Pain D010146 64 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Leukemia D007938 74 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Kawasaki S et al. [Effects of a steroid and macrolide antibiotic on IL-8 production by neutrophils]. 1997 Jpn J Antibiot pmid:9597446
Mineshita M et al. [Effect of macrolide antibiotics on actin polymerization reactions of neutrophils]. 1997 Jpn J Antibiot pmid:9597447
Sato K et al. [Pyocyanine synthesis by Pseudomonas aeruginosa in chronic airway infection and the effect of erythromycin on its biological activity]. 1997 Jpn J Antibiot pmid:9597453
Ohara K et al. [Effects of pretreatment by erythromycin or rokitamycin on aminoglycoside inactivating enzyme of Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597454
Kobayashi O et al. [Actions of macrolide antibiotics on alginate production by Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597455
Kondo K et al. [Quantitative evaluation of the inhibitory action of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597456
Kudo S [Preliminary survey on DPB (diffuse panbronchitis) in Japan and a survey on the status of DPB in China]. 1997 Jpn J Antibiot pmid:9597457
Tei A et al. [Effects and actions of EM (erythromycin), CAM (clarithromycin), and JM (josamycin) on IL-4 and IL-5 production by monocytes]. 1997 Jpn J Antibiot pmid:9597458
Hoshina S et al. [C kinase activation and induction of HL 60 promyelocytic leukemia cell differentiation caused by roxithromycin]. 1997 Jpn J Antibiot pmid:9597464
Takada T et al. [Study of specific mRNA expression by peripheral monocytes of patients with diffuse panbronchitis using cDNA representational difference analysis (RDA)]. 1997 Jpn J Antibiot pmid:9597465
Kaseta M et al. [Study of therapeutic effects of macrolide antibiotics on patients with anti-HTLV-1 antibody positive DPB (diffuse panbronchitis)]. 1997 Jpn J Antibiot pmid:9597466
Miyashima S et al. [Effects of erythromycin on a mouse hypersensitivity pneumonia model]. 1997 Jpn J Antibiot pmid:9597469
Nonaka M et al. [Effects of macrolide antibiotics on fibroblasts]. 1997 Jpn J Antibiot pmid:9597470
Hori S et al. [Effects of macrolide drugs on endogenous glucocorticoids]. 1997 Jpn J Antibiot pmid:9597471
Hikariyama T et al. [Study of suppression of neutrophil functions and prevention of vascular endothelial injury by macrolide antibiotics]. 1998 Jpn J Antibiot pmid:9597473
Tamaoki J et al. [Effects of macrolide antibiotics on iNOS gene expression and NO production by alveolar macrophages]. 1998 Jpn J Antibiot pmid:9597474
Takeda H et al. [Bone absorption suppression by broad spectrum antibiotics]. 1998 Jpn J Antibiot pmid:9597475
Kawasaki S et al. [Effects of a steroid and macrolide antibiotic on adhesion of neutrophils to the airway epithelial cells]. 1998 Jpn J Antibiot pmid:9597483
Nakada K et al. [Therapeutic guideline for diffuse panbronchitis (draft). Subcommittee on Diffuse Lung Diseases, Research Committee on Respiratory Diseases Organized by the Ministry of Health and Welfare]. 1998 Jpn J Antibiot pmid:9597494
Shirai R et al. [Evaluation of the duration of medication with erythromycin for treatment of diffuse panbronchitis--a comparison between interruption of medication and continued administration]. 1998 Jpn J Antibiot pmid:9597496