MeSH term | MeSH ID | Detail |
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Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Rashed SM et al. | Genetic characteristics of drug-resistant Vibrio cholerae O1 causing endemic cholera in Dhaka, 2006-2011. | 2012 | J. Med. Microbiol. | pmid:22977073 |
Padovan J et al. | Investigating the barriers to bioavailability of macrolide antibiotics in the rat. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:22113743 |
Mokhber-Dezfooli MR et al. | Effect of abomasal emptying rate on the apparent efficiency of colostral immunoglobulin G absorption in neonatal Holstein-Friesian calves. | 2012 | J. Dairy Sci. | pmid:22981576 |
Walkey AJ and Wiener RS | Macrolide antibiotics and survival in patients with acute lung injury. | 2012 | Chest | pmid:22116799 |
Wills RH et al. | Structural characterization of polyketides using high mass accuracy tandem mass spectrometry. | 2012 | Anal. Chem. | pmid:22985101 |
Sugimoto T et al. | Synthesis and structure-activity relationship of a novel class of 15-membered macrolide antibiotics known as '11a-azalides'. | 2012 | Bioorg. Med. Chem. | pmid:22925450 |
Sugimoto T et al. | Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22858102 |
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Dekio I | Follicular spicules associated with Propionibacterium acnes with response to erythromycin: Lack of evidence for the species? | 2012 | J. Dermatol. | pmid:22224953 |
Oo C and Shah B | Does erythromycin have anti-inflammatory effects independent of its antimicrobial action? | 2012 | J Clin Pharmacol | pmid:21868717 |
März A et al. | Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. | 2012 | Anal Bioanal Chem | pmid:21822777 |
Sommerfeld Ross S and Fiegel J | Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms. | 2012 | Int. J. Antimicrob. Agents | pmid:22727773 |
Zaknoon F et al. | Antibacterial properties of an oligo-acyl-lysyl hexamer targeting Gram-negative species. | 2012 | Antimicrob. Agents Chemother. | pmid:22751534 |
Gant CM et al. | Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22751535 |
Kim J et al. | Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea. | 2012 | J. Microbiol. | pmid:22752920 |
Arakawa K et al. | The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. | 2012 | Chembiochem | pmid:22761035 |
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Martins ER et al. | Dominance of serotype Ia among group B Streptococci causing invasive infections in nonpregnant adults in Portugal. | 2012 | J. Clin. Microbiol. | pmid:22219307 |
Palumbo Piccionello A et al. | Synthesis and preliminary antibacterial evaluation of Linezolid-like 1,2,4-oxadiazole derivatives. | 2012 | Eur J Med Chem | pmid:22365410 |
Pešić D et al. | Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides. | 2012 | J. Med. Chem. | pmid:22380766 |
Shore EM and Yudin MH | Choice of antibiotic for group B streptococcus in women in labour based on antibiotic sensitivity testing. | 2012 | J Obstet Gynaecol Can | pmid:22385665 |
Ullrich K et al. | Neuroretinitis following bull ant sting. | 2012 | BMJ Case Rep | pmid:22865803 |
Pollett S et al. | Campylobacter antimicrobial resistance in Peru: a ten-year observational study. | 2012 | BMC Infect. Dis. | pmid:22898609 |
Licona-Cassani C et al. | Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. | 2012 | Antonie Van Leeuwenhoek | pmid:22847261 |
Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. | 2012 | Prescrire Int | pmid:22852287 | |
Kim EY et al. | The effectiveness of erythromycin in reducing stent-related tissue hyperplasia: an experimental study with a rat esophageal model. | 2012 | Acta Radiol | pmid:22855416 |
Oldenburg M et al. | TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. | 2012 | Science | pmid:22821982 |
Cetin M et al. | Clarithromycin-Induced Long QT Syndrome: A Case Report. | 2012 | Case Rep Med | pmid:22489247 |
Pinto A et al. | 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. | 2012 | Org. Lett. | pmid:22519860 |
Yuzawa S et al. | Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. | 2012 | Biochemistry | pmid:22509729 |
Wang Y et al. | The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes. | 2012 | Beilstein J Org Chem | pmid:23019458 |
Shimizu S et al. | Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. | 2012 | J. Agric. Food Chem. | pmid:22694300 |
Perry DM et al. | Identification and characterization of protein phosphatase 2C activation by ceramide. | 2012 | J. Lipid Res. | pmid:22615346 |
Geddes BA and Oresnik IJ | Genetic characterization of a complex locus necessary for the transport and catabolism of erythritol, adonitol and L-arabitol in Sinorhizobium meliloti. | 2012 | Microbiology (Reading, Engl.) | pmid:22609752 |
Karlgren M et al. | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | 2012 | J. Med. Chem. | pmid:22541068 |
Noormohamed A and Fakhr MK | Incidence and antimicrobial resistance profiling of Campylobacter in retail chicken livers and gizzards. | 2012 | Foodborne Pathog. Dis. | pmid:22545960 |
Pinto TF et al. | Tolerance to enteral nutrition therapy in traumatic brain injury patients. | 2012 | Brain Inj | pmid:22571511 |
Deane AM et al. | Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. | 2012 | Am. J. Clin. Nutr. | pmid:22572649 |
Senhorinho GN et al. | Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. | 2012 | Anaerobe | pmid:22609780 |
Bidet P et al. | Identification of group A streptococcal emm types commonly associated with invasive infections and antimicrobial resistance by the use of multiplex PCR and high-resolution melting analysis. | 2012 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:22610663 |
Lu X et al. | Antimicrobial effect of diallyl sulphide on Campylobacter jejuni biofilms. | 2012 | J. Antimicrob. Chemother. | pmid:22550133 |
Liu X et al. | [The effect of biyuanshu oral liquid on the formation of Pseudomonas aeruginosa biofilms in vitro]. | 2012 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:23156807 |
Chen X et al. | Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23122862 |
Izumikawa M et al. | JBIR-78 and JBIR-95: phenylacetylated peptides isolated from Kibdelosporangium sp. AK-AA56. | 2012 | J. Nat. Prod. | pmid:22264203 |
Li M et al. | Effect of erythromycin on cigarette-induced histone deacetylase protein expression and nuclear factor-κB activity in human macrophages in vitro. | 2012 | Int. Immunopharmacol. | pmid:22265969 |
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Ocular prophylaxis for gonococcal ophthalmia neonatorum: reaffirmation recommendation statement. | 2012 | Am Fam Physician | pmid:22335221 | |
Jordan PA and Miller SJ | An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:22319027 |